Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

Autor: Plaat, D. van der, Vonk, J.M., Terzikhan, N., Jong, K. de, Vries, M. de, Bastide-van Gemert, S. la, Diemen, C.C. van, Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R.C.H., Postma, D.S., Duijn, C.M. van, Boezen, H.M., Heijmans, B.T., Hoen, P.A.C.T., Meurs, J. van, Isaacs, A., Jansen, R., Franke, L., Boomsma, D.I., Pool, R., Dongen, J. van, Hottenga, J.J., Greevenbroek, M.M.J. van, Stehouwer, C.D.A., Kallen, C.J.H. van der, Schalkwijk, C.G., Wijmenga, C., Zhernakova, S., Tigchelaar, E.E., Slagboom, P.E., Beekman, M., Deelen, J., Heemst, D. van, Veldink, J.H., Berg, L.H. van den, Hofman, B.A., Uitterlinden, A.G., Jhamai, P.M., Verbiest, M., Suchiman, H.E.D., Verkerk, M., Breggen, R. van der, Rooij, J. van, Lakenberg, N., Mei, H., Iterson, M. van, Galen, M. van, Bot, J., Zhernakova, D.V., Hof, P.V., Deelen, P., Nooren, I., Moed, M., Vermaat, M., Luijk, R., Bonder, M.J., Dijk, F. van, Arindrarto, W., Kielbasa, S.M., Swertz, M.A., Zwet, E.W. van, Hoen, P.B. 't, BIOS Consortium

Publikováno v: Human Molecular Genetics, 28(15), 2477. Oxford University Press
Human Molecular Genetics, 28(15), 2477-2485. Oxford University Press
Human Molecular Genetics
BIOS Consortium, Boomsma, D, Pool, R, van Dongen, J & Hottenga, J J 2019, ' Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression ', Human molecular genetics, vol. 28, no. 15, pp. 2477-2485 . https://doi.org/10.1093/hmg/ddz067
Human Molecular Genetics, 28(15), 2477-2485
HUMAN MOLECULAR GENETICS
Human molecular genetics, 28(15), 2477-2485. Oxford University Press

Many workers are daily exposed to occupational agents like gases/fumes, mineral dust or biological dust, which could induce adverse health effects. Epigenetic mechanisms, such as DNA methylation, have been suggested to play a role. We therefore aimed

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https://cris.maastrichtuniversity.nl/en/publications/6a1f41cf-27f5-46f8-9d70-91af32912200