Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Hoe-Sup Byun"'
Autor:
Aimee E. Christian, Hoe-Sup Byun, Ning Zhong, Meni Wanunu, Thomas Marti, Andreas Fürer, François Diederich, Robert Bittman, George H. Rothblat
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 8, Pp 1475-1482 (1999)
Previous studies from this laboratory have demonstrated that low concentrations of cyclodextrins (
Externí odkaz:
https://doaj.org/article/2c011998f83a4c2897aa9aa0f445abfb
Autor:
Julie D. Saba, Andrew R. Lee, Robert Bittman, Hoe Sup Byun, Yaqiong Gong, Padmavathi Bandhuvula, Babak Oskouian, Henrik Fyrst
Supplementary Methods, Figures 1-9, Table 1 from Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330cbbbe5d08204be44d159d77ab5eed
https://doi.org/10.1158/0008-5472.22383575
https://doi.org/10.1158/0008-5472.22383575
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Phospholipids Handbook ISBN: 9780203743577
Phospholipids Handbook
Phospholipids Handbook
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7009dd5fe255f0c7e14fe223317af6f
https://doi.org/10.1201/9780203743577-5
https://doi.org/10.1201/9780203743577-5
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Chemistry and Physics of Lipids. 165:794-801
Sphingadienes are chemopreventive agents that act by blocking signaling pathways that are activated in cancer. A practical synthesis of 4,6- and 4,8-sphingadienes on a scale of gram quantities is reported here in order to allow evaluation of the biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fba2755d551dd18c786e67f44b0de6f
https://doi.org/10.1016/j.chemphyslip.2012.10.002
https://doi.org/10.1016/j.chemphyslip.2012.10.002
Autor:
Meng Zhang, Hoe-Sup Byun, Fang Lu, Julie D. Saba, Henrik Fyrst, Ashok Kumar, Ashok Kumar Pandurangan, Robert Bittman
Publikováno v:
Carcinogenesis. 33:1726-1735
Sphingadienes (SDs) derived from soy and other natural sphingolipids are cytotoxic to colon cancer cells via an Akt-dependent mechanism and reduce adenoma formation in Apc(Min/+) mice. Wnt signaling is fundamental to colon carcinogenesis and is the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451a4aad6e2787803ba044d43f45fb92
https://doi.org/10.1093/carcin/bgs174
https://doi.org/10.1093/carcin/bgs174
Publikováno v:
Cellular Signalling. 23:1144-1152
The bioactive signaling molecule d -erythro-sphingosine-1-phosphate (S1P) is irreversibly degraded by the enzyme S1P lyase (SPL). The reaction of SPL with C18-S1P generates ethanolamine phosphate and a long-chain fatty aldehyde, trans-2-hexadecenal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0747ad2ab7f98117befc8fefafe98c0
https://doi.org/10.1016/j.cellsig.2011.02.009
https://doi.org/10.1016/j.cellsig.2011.02.009
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Chemistry and Physics of Lipids. 163:809-813
Deuteration at C-4 and C-5 of sphingosine was achieved via a hydrogen–deuterium exchange reaction of a β-ketophosphonate intermediate catalyzed by ND4Cl in D2O/tetrahydrofuran. To install deuterium at C-3 of sphingosine and sphingomyelin, sodium b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f2c04e3302ae64fb797fa24c5bb0a3
https://doi.org/10.1016/j.chemphyslip.2010.09.001
https://doi.org/10.1016/j.chemphyslip.2010.09.001
Publikováno v:
ChemMedChem. 5:1045-1052
Analogues of 1-O-hexadecyl-sn-3-glycerophosphonocholine (compounds 1-4) or sn-3-glycerophosphocholine (compound 5) bearing a carbamate or dicarbarnate moiety at the sn-2 position were synthesized and evaluated for their antiproliferative activity aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7768c984e9e5227fd99b3b071b61c1
https://doi.org/10.1002/cmdc.201000060
https://doi.org/10.1002/cmdc.201000060
Publikováno v:
Organic Letters. 12:2974-2977
Stereocontrolled syntheses of alpha-C-GalCer (2) and its alpha-C-acetylenic analogue 6 were accomplished in high efficiency by a convergent construction strategy from 1-hexadecene and d-galactose. The key transformations include Sonogashira coupling,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8297c03aae1d95165d54c7b8bcf2b4a6
https://doi.org/10.1021/ol1009976
https://doi.org/10.1021/ol1009976
Publikováno v:
Biochemistry and Cell Biology. 87:401-414
Glycosylated antitumor ether lipids (GAELs) have superior anticancer properties relative to the alkyllysophospholipid class, but there have been no studies of the mechanisms of these compounds. The prototype GAEL, 1-O-hexadecyl-2-O-methyl-3-O-(2′-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344c1beb2e8b654885bc769d2cc04ca8
https://doi.org/10.1139/o08-147
https://doi.org/10.1139/o08-147