Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Hoe-Sup Byun"'
Autor:
Julie D. Saba, Andrew R. Lee, Robert Bittman, Hoe Sup Byun, Yaqiong Gong, Padmavathi Bandhuvula, Babak Oskouian, Henrik Fyrst
Supplementary Methods, Figures 1-9, Table 1 from Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330cbbbe5d08204be44d159d77ab5eed
https://doi.org/10.1158/0008-5472.22383575
https://doi.org/10.1158/0008-5472.22383575
Autor:
Henrik Fyrst, Xinyi Zhang, Deron R. Herr, Hoe Sup Byun, Robert Bittman, Van H. Phan, Greg L. Harris, Julie D. Saba
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 3, Pp 597-606 (2008)
Sphingolipids comprise a complex group of lipids concentrated in membrane rafts and whose metabolites function as signaling molecules. Sphingolipids are conserved in Drosophila, in which their tight regulation is required for proper development and t
Externí odkaz:
https://doaj.org/article/0740620d207e4c26b1abb1543ef68599
Autor:
Aimee E. Christian, Hoe-Sup Byun, Ning Zhong, Meni Wanunu, Thomas Marti, Andreas Fürer, François Diederich, Robert Bittman, George H. Rothblat
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 8, Pp 1475-1482 (1999)
Previous studies from this laboratory have demonstrated that low concentrations of cyclodextrins (
Externí odkaz:
https://doaj.org/article/2c011998f83a4c2897aa9aa0f445abfb
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Phospholipids Handbook ISBN: 9780203743577
Phospholipids Handbook
Phospholipids Handbook
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7009dd5fe255f0c7e14fe223317af6f
https://doi.org/10.1201/9780203743577-5
https://doi.org/10.1201/9780203743577-5
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Chemistry and Physics of Lipids. 165:794-801
Sphingadienes are chemopreventive agents that act by blocking signaling pathways that are activated in cancer. A practical synthesis of 4,6- and 4,8-sphingadienes on a scale of gram quantities is reported here in order to allow evaluation of the biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fba2755d551dd18c786e67f44b0de6f
https://doi.org/10.1016/j.chemphyslip.2012.10.002
https://doi.org/10.1016/j.chemphyslip.2012.10.002
Autor:
Meng Zhang, Hoe-Sup Byun, Fang Lu, Julie D. Saba, Henrik Fyrst, Ashok Kumar, Ashok Kumar Pandurangan, Robert Bittman
Publikováno v:
Carcinogenesis. 33:1726-1735
Sphingadienes (SDs) derived from soy and other natural sphingolipids are cytotoxic to colon cancer cells via an Akt-dependent mechanism and reduce adenoma formation in Apc(Min/+) mice. Wnt signaling is fundamental to colon carcinogenesis and is the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451a4aad6e2787803ba044d43f45fb92
https://doi.org/10.1093/carcin/bgs174
https://doi.org/10.1093/carcin/bgs174
Publikováno v:
Cellular Signalling. 23:1144-1152
The bioactive signaling molecule d -erythro-sphingosine-1-phosphate (S1P) is irreversibly degraded by the enzyme S1P lyase (SPL). The reaction of SPL with C18-S1P generates ethanolamine phosphate and a long-chain fatty aldehyde, trans-2-hexadecenal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0747ad2ab7f98117befc8fefafe98c0
https://doi.org/10.1016/j.cellsig.2011.02.009
https://doi.org/10.1016/j.cellsig.2011.02.009
Autor:
Hoe-Sup Byun, Robert Bittman
Publikováno v:
Chemistry and Physics of Lipids. 163:809-813
Deuteration at C-4 and C-5 of sphingosine was achieved via a hydrogen–deuterium exchange reaction of a β-ketophosphonate intermediate catalyzed by ND4Cl in D2O/tetrahydrofuran. To install deuterium at C-3 of sphingosine and sphingomyelin, sodium b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f2c04e3302ae64fb797fa24c5bb0a3
https://doi.org/10.1016/j.chemphyslip.2010.09.001
https://doi.org/10.1016/j.chemphyslip.2010.09.001
Publikováno v:
ChemMedChem. 5:1045-1052
Analogues of 1-O-hexadecyl-sn-3-glycerophosphonocholine (compounds 1-4) or sn-3-glycerophosphocholine (compound 5) bearing a carbamate or dicarbarnate moiety at the sn-2 position were synthesized and evaluated for their antiproliferative activity aga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7768c984e9e5227fd99b3b071b61c1
https://doi.org/10.1002/cmdc.201000060
https://doi.org/10.1002/cmdc.201000060
Publikováno v:
Biochemistry and Cell Biology. 87:401-414
Glycosylated antitumor ether lipids (GAELs) have superior anticancer properties relative to the alkyllysophospholipid class, but there have been no studies of the mechanisms of these compounds. The prototype GAEL, 1-O-hexadecyl-2-O-methyl-3-O-(2′-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344c1beb2e8b654885bc769d2cc04ca8
https://doi.org/10.1139/o08-147
https://doi.org/10.1139/o08-147