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pro vyhledávání: '"Hoda M. Gebril"'
Autor:
Hoda M. Gebril, Aravind Aryasomayajula, Mariana Reis Nogueira de Lima, Kathryn E. Uhrich, Prabhas V. Moghe
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-24 (2024)
Abstract Background Alzheimer's disease (AD) is considered to have a multifactorial etiology. The hallmark of AD is progressive neurodegeneration, which is characterized by the deepening loss of memory and a high mortality rate in the elderly. The ne
Externí odkaz:
https://doaj.org/article/e928cd5e312a460dbc51d678e149f4ad
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Adenosine kinase (ADK), the major adenosine-metabolizing enzyme, plays a key role in brain development and disease. In humans, mutations in the Adk gene have been linked to developmental delay, stunted growth, and intellectual disability. To
Externí odkaz:
https://doaj.org/article/0bd6d0dbb5974d448b5c43cff7b1ac1a
Publikováno v:
Neurochemistry International. 109:54-67
A hexose phosphate recycling model previously developed to infer fluxes through the major glucose consuming pathways in cultured cerebellar granule neurons (CGNs) from neonatal rats metabolizing [1,2-13C2]glucose was revised by considering reverse fl
Publikováno v:
Neurochemistry International. 93:26-39
Glycolysis, mitochondrial substrate oxidation, and the pentose phosphate pathway (PPP) are critical for neuronal bioenergetics and oxidation-reduction homeostasis, but quantitating their fluxes remains challenging, especially when processes such as h
Publikováno v:
Neurochemistry international. 109
A hexose phosphate recycling model previously developed to infer fluxes through the major glucose consuming pathways in cultured cerebellar granule neurons (CGNs) from neonatal rats metabolizing [1,2-13C2]glucose was revised by considering reverse fl