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Pre-treatment with systemic agents for advanced NSCLC elicits changes in the phenotype of autologous T cell therapy products.

Autor: O'Brien Gore C; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, UK., Billman A; Analytical Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Hunjan S; Oncology Cell Therapy Unit, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Colebrook J; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Choy D; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, UK., Li W; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Haynes J; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Wade J; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Hobern E; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., McDonald L; Oncology & Hematology Clinical Trials (OHCT), Guy's Hospital, 1st Floor Chapel Wing, Great Maze Pond, SE1 9RT London, UK., Papa S; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, UK., Brugman M; Analytical Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK., Kordasti S; School of Cancer and Pharmaceutical Sciences, King's College London, Faculty of Life Sciences and Medicine, Guy's Hospital, London, UK., Montiel-Equihua C; Product Development, Cell and Gene Therapy, GSK Medicine Research Centre, Stevenage, SG1 2NY Hertfordshire, UK.

Publikováno v: Molecular therapy oncolytics [Mol Ther Oncolytics] 2023 Nov 10; Vol. 31, pp. 100749. Date of Electronic Publication: 2023 Nov 10 (Print Publication: 2023).