Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hoanh Tran"'
Autor:
Daniel Frank, Maria Bergamasco, Michael J Mlodzianoski, Andrew Kueh, Ellen Tsui, Cathrine Hall, Georgios Kastrappis, Anne Kathrin Voss, Catriona McLean, Maree Faux, Kelly L Rogers, Bang Tran, Elizabeth Vincan, David Komander, Grant Dewson, Hoanh Tran
Publikováno v:
eLife, Vol 12 (2023)
ZRANB1 (human Trabid) missense mutations have been identified in children diagnosed with a range of congenital disorders including reduced brain size, but how Trabid regulates neurodevelopment is not understood. We have characterized these patient mu
Externí odkaz:
https://doaj.org/article/11cef469c8eb42c9944ccee57a624fbc
Autor:
Yvonne Yeung, David K. Lau, Fiona Chionh, Hoanh Tran, Janson W. T. Tse, Andrew J. Weickhardt, Mehrdad Nikfarjam, Andrew M. Scott, Niall C. Tebbutt, John M. Mariadason
Publikováno v:
Molecular Oncology, Vol 11, Iss 9, Pp 1130-1142 (2017)
Advanced biliary tract cancer (BTC) has a poor prognosis and limited treatment options. The PI3K/Akt/mTOR signalling pathway is hyperactivated in a subset of BTCs, and clinical activity of the mTOR inhibitor everolimus has been observed in some patie
Externí odkaz:
https://doaj.org/article/9b37848bc6944ef2a7e5466ae11a6883
Autor:
Bang Manh Tran, Dustin James Flanagan, Gregor Ebert, Nadia Warner, Hoanh Tran, Theodora Fifis, Georgios Kastrappis, Christopher Christophi, Marc Pellegrini, Joseph Torresi, Toby James Phesse, Elizabeth Vincan
Publikováno v:
Cancers, Vol 12, Iss 6, p 1435 (2020)
An emerging theme for Wnt-addicted cancers is that the pathway is regulated at multiple steps via various mechanisms. Infection with hepatitis B virus (HBV) is a major risk factor for liver cancer, as is deregulated Wnt signaling, however, the intera
Externí odkaz:
https://doaj.org/article/d445fe9839334f5c86dfed602697940c
Autor:
Jeannine Diesch, Elaine Sanij, Omer Gilan, Christopher Love, Hoanh Tran, Nicholas I Fleming, Jason Ellul, Marcia Amalia, Izhak Haviv, Richard B Pearson, Eugene Tulchinsky, John M Mariadason, Oliver M Sieber, Ross D Hannan, Amardeep S Dhillon
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e88950 (2014)
Tumor invasion and metastasis involves complex remodeling of gene expression programs governing epithelial homeostasis. Mutational activation of the RAS-ERK is a frequent occurrence in many cancers and has been shown to drive overexpression of the AP
Externí odkaz:
https://doaj.org/article/d7fe9ee98a4f408bb231db36ea198d14
Autor:
Marinella G Callow, Hoanh Tran, Lilian Phu, Ted Lau, James Lee, Wendy N Sandoval, Peter S Liu, Sheila Bheddah, Janet Tao, Jennie R Lill, Jo-Anne Hongo, David Davis, Donald S Kirkpatrick, Paul Polakis, Mike Costa
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22595 (2011)
Canonical Wnt signaling is controlled intracellularly by the level of β-catenin protein, which is dependent on Axin scaffolding of a complex that phosphorylates β-catenin to target it for ubiquitylation and proteasomal degradation. This function of
Externí odkaz:
https://doaj.org/article/dd787cda777a424996475d2d515fd403
Autor:
John M. Mariadason, Andrew K. Shiau, Panagis Filippakopoulos, Timothy C. Gahman, Beatriz Diez-Dacal, Mark A. Dawson, Amardeep S. Dhillon, Diego Arango, Oliver M. Sieber, Rui Wu, Toby Phesse, Hoanh Tran, Aparna Jayachandran, Anderly C. Chueh, Rebecca Nightingale, Lars Tögel
Genotypes of colorectal cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b8da6d55007eda7753d09a5e5bcc2d
https://doi.org/10.1158/1535-7163.22503354.v1
https://doi.org/10.1158/1535-7163.22503354.v1
Autor:
John M. Mariadason, Andrew K. Shiau, Panagis Filippakopoulos, Timothy C. Gahman, Beatriz Diez-Dacal, Mark A. Dawson, Amardeep S. Dhillon, Diego Arango, Oliver M. Sieber, Rui Wu, Toby Phesse, Hoanh Tran, Aparna Jayachandran, Anderly C. Chueh, Rebecca Nightingale, Lars Tögel
BET protein expression in primary colorectal cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394a875cf8e6b1fce6ef1625bfc985dc
https://doi.org/10.1158/1535-7163.22503369.v1
https://doi.org/10.1158/1535-7163.22503369.v1
Autor:
John M. Mariadason, Andrew K. Shiau, Panagis Filippakopoulos, Timothy C. Gahman, Beatriz Diez-Dacal, Mark A. Dawson, Amardeep S. Dhillon, Diego Arango, Oliver M. Sieber, Rui Wu, Toby Phesse, Hoanh Tran, Aparna Jayachandran, Anderly C. Chueh, Rebecca Nightingale, Lars Tögel
Legends to supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c13e69bbd0075c023ab693f86e66ebb
https://doi.org/10.1158/1535-7163.22503360.v1
https://doi.org/10.1158/1535-7163.22503360.v1
Autor:
John M. Mariadason, Andrew K. Shiau, Panagis Filippakopoulos, Timothy C. Gahman, Beatriz Diez-Dacal, Mark A. Dawson, Amardeep S. Dhillon, Diego Arango, Oliver M. Sieber, Rui Wu, Toby Phesse, Hoanh Tran, Aparna Jayachandran, Anderly C. Chueh, Rebecca Nightingale, Lars Tögel
BET protein expression in 20 colon cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4979ff1fb1c08dcdf49f5c1bd12cd134
https://doi.org/10.1158/1535-7163.22503372
https://doi.org/10.1158/1535-7163.22503372
Autor:
John M. Mariadason, Andrew K. Shiau, Panagis Filippakopoulos, Timothy C. Gahman, Beatriz Diez-Dacal, Mark A. Dawson, Amardeep S. Dhillon, Diego Arango, Oliver M. Sieber, Rui Wu, Toby Phesse, Hoanh Tran, Aparna Jayachandran, Anderly C. Chueh, Rebecca Nightingale, Lars Tögel
Sequences of primers used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b6ff63016654126252ae3521d1042c
https://doi.org/10.1158/1535-7163.22503357
https://doi.org/10.1158/1535-7163.22503357