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Combined MRI, high-resolution manometry and a randomised trial of bisacodyl versus hyoscine show the significance of an enlarged colon in constipation: the RECLAIM study.

Autor: Wilkinson-Smith V; School of Medicine, University of Nottingham, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, Nottingham, UK., Scott M; Academic Surgical Unit, Barts and The London School of Medicine and Dentistry, London, UK., Menys A; Motilent Ltd, London, UK., Wiklendt L; College of Medicine & Public Health, Flinders University, Adelaide, South Australia, Australia., Marciani L; Translational Medical Sciences, Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK.; Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham, UK., Atkinson D; Centre for Medical Imaging, UCL, London, UK., Sansone S; Nottingham Digestive Diseases Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK., Zdanaviciene A; Barts and the London School of Medicine and Dentistry, Queen Mary University, London, UK., Coupland C; Centre for Academic Primary Care, University of Nottingham, Nottingham, UK., Knowles CH; Blizzard Institute, Queen Mary University, London, UK., Dinning P; Gastroenterology and Surgery, Flinders Medical Center, Adelaide, South Australia, Australia., Taylor SA; Imaging Department, University College London Hospitals NHS Foundation Trust, London, UK., Gowland P; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK., Hoad CL; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK., Corsetti M; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.; Nottingham Digestive Diseases Biomedical Research Unit, University of Nottingham, Nottingham, UK., Spiller RC; Nottingham Digestive Diseases Centre, NIHR Nottingham Biomedical Research Centre, Nottingham, UK robin.spiller@nottingham.ac.uk.; Translational Medical Science, University of Nottingham, Nottingham, UK.

Publikováno v: Gut [Gut] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.

A longitudinal study assessing the impact of elexacaftor/tezacaftor/ivacaftor on gut transit and function in people with cystic fibrosis using magnetic resonance imaging (MRI).

Autor: Yule A; Academic Unit of Lifespan & Population Health, School of Medicine, University of Nottingham, Nottingham, UK; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Ng C; Academic Unit of Lifespan & Population Health, School of Medicine, University of Nottingham, Nottingham, UK; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Recto A; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; School of Medicine, University of Nottingham, Nottingham, UK., Lockwood F; School of Medicine, University of Nottingham, Nottingham, UK., Dellschaft NS; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, UK., Hoad CL; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, UK., Zagoya C; Brandenburg Medical School (MHB) University. Klinikum Westbrandenburg, Brandenburg an der Havel, Germany., Mainz JG; Brandenburg Medical School (MHB) University. Klinikum Westbrandenburg, Brandenburg an der Havel, Germany., Major G; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Service d'Endocrinologie, Diabétologie et Métabolisme, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland., Barr HL; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Gowland PA; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, UK., Stewart I; Margaret Turner Warwick Centre for Fibrosing Lung Disease, National Heart and Lung Institute, Imperial College London, London, UK; Imperial NIHR Biomedical Research Centre, Imperial College London, London, UK., Marciani L; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, UK., Spiller RC; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; Nottingham Digestive Diseases Centre, University of Nottingham, Nottingham, UK., Smyth AR; Academic Unit of Lifespan & Population Health, School of Medicine, University of Nottingham, Nottingham, UK; NIHR Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK; School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. Electronic address: Alan.smyth@qub.ac.uk.

Publikováno v: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2024 Sep; Vol. 23 (5), pp. 984-990. Date of Electronic Publication: 2024 Sep 05.