Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hoa Dinh Le"'
Autor:
James S. C. Gilchrist, Hoa Dinh Le, Vladimir Yurkov, Kristy D. Ranson, Danielle DeMoissac, Larry V. Hryshko, Alexander Omelchenko, Mark Hnatowich
Publikováno v:
Cell Calcium. 51:164-170
μ-Calpain is a Ca(2+)-activated protease abundant in mammalian tissues. Here, we examined the effects of μ-calpain on three alternatively spliced variants of NCX1 using the giant, excised patch technique. Membrane patches from Xenopus oocytes expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d204dea9e856a700ef54d1d4e2ab36
https://doi.org/10.1016/j.ceca.2011.12.006
https://doi.org/10.1016/j.ceca.2011.12.006
Autor:
Alexander Omelchenko, Tien-Chien Pan, Glen F. Tibbits, Christian R. Marshall, Pung-Pung Hwang, Hoa Dinh Le, Larry V. Hryshko
Publikováno v:
Journal of Biological Chemistry. 280:28903-28911
The complete cDNA sequence of the tilapia cardiac Na(+)/Ca2+ exchanger (NCX-TL1.0) was determined. The 3.1-kb transcript encodes a protein 957 amino acids in length, with a predicted signal peptide cleaved at residue 31 and two potential N-glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662f21dfdca61ef963e8813fec0d7d16
https://doi.org/10.1074/jbc.m504807200
https://doi.org/10.1074/jbc.m504807200
Autor:
Madalina Condrescu, Alexandra Uliyanova, Larry V. Hryshko, Hoa Dinh Le, John P. Reeves, Alexander Omelchenko
Publikováno v:
The Journal of Physiology. 563:105-117
Chinese hamster ovary cells expressing the bovine cardiac Na+–Ca2+ exchanger (NCX1.1) accumulated Cd2+ after a lag period of several tens of seconds. The lag period reflects the progressive allosteric activation of exchange activity by Cd2+ as it a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2916bdd4b9780cbbfec7c9148a4925bd
https://doi.org/10.1113/jphysiol.2004.077743
https://doi.org/10.1113/jphysiol.2004.077743
Autor:
Ron Bouchard, Alexander Omelchenko, Kenzo Takahashi, Kenneth D. Philipson, Akemichi Baba, Debora A. Nicoll, Hoa Dinh Le, Toshio Matsuda, Mark Hnatowich, Platon Choptiany, Larry V. Hryshko
Publikováno v:
Molecular Pharmacology. 65:802-810
SEA0400 (SEA) blocks cardiac and neuronal Na+-Ca2+ exchange with the highest affinity of any known inhibitor, yet very little is known about its molecular mechanism of action. Previous data from our lab suggested that SEA stabilizes or modulates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7576151492cb8b23c65963c3ea9bbb
https://doi.org/10.1124/mol.65.3.802
https://doi.org/10.1124/mol.65.3.802
Autor:
Alexander Omelchenko, Mark Hnatowich, Ron Bouchard, Neeraj Visen, Platon Choptiany, Larry V. Hryshko, Hoa Dinh Le
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 306:1050-1057
The electrophysiological effects of the benzothiazepine 7-chloro-3,5-dihydro-5-phenyl-1H-4,1-benzothiazepine-2-one (CGP-37157) (CGP) were investigated on the canine (NCX1.1) and Drosophila (CALX1.1) plasmalemmal Na+-Ca2+ exchangers. These exchangers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa89e3fc77d0c663fe15a5e1d0ae5f7
https://doi.org/10.1124/jpet.103.053389
https://doi.org/10.1124/jpet.103.053389
Autor:
Alexander Omelchenko, Hoa Dinh Le, Christian R. Marshall, Xiao-Hua Xue, Larry V. Hryshko, Chadwick L. Elias, Glen F. Tibbits
Publikováno v:
American Journal of Physiology-Cell Physiology. 283:C512-C520
The cardiac Na+/Ca2+exchanger (NCX) in trout exhibits profoundly lower temperature sensitivity in comparison to the mammalian NCX. In this study, we attempt to characterize the regions of the NCX molecule that are responsible for its temperature sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b28c4fd0d5d2c2ad47431b9811c96e4
https://doi.org/10.1152/ajpcell.00558.2001
https://doi.org/10.1152/ajpcell.00558.2001
Autor:
Larry V. Hryshko, Lei Zheng, Alexander Omelchenko, Vladimir Yurkov, Jay C. Nix, Mark Hnatowich, Meitian Wang, Hoa Dinh Le, Mousheng Wu
Publikováno v:
The Journal of biological chemistry. 285(4)
Na(+)/Ca(2+) exchangers (NCX) constitute a major Ca(2+) export system that facilitates the re-establishment of cytosolic Ca(2+) levels in many tissues. Ca(2+) interactions at its Ca(2+) binding domains (CBD1 and CBD2) are essential for the allosteric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4efb173b9b2509234e7ad007c5c941
https://pubmed.ncbi.nlm.nih.gov/19815561
https://pubmed.ncbi.nlm.nih.gov/19815561
Autor:
Hoa Dinh Le, Steve F. Perry, Christian R. Marshall, Vladimir Yurkov, Larry V. Hryshko, Caly On, Mark Hnatowich, Glen F. Tibbits, Alexander Omelchenko
Publikováno v:
American journal of physiology. Cell physiology. 296(1)
Members of the Na+/Ca2+exchanger (NCX) family are important regulators of cytosolic Ca2+in myriad tissues and are highly conserved across a wide range of species. Three distinct NCX genes and numerous splice variants exist in mammals, many of which h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6b5c0e942c6d780d31fa37769bfd3e7
https://pubmed.ncbi.nlm.nih.gov/18971388
https://pubmed.ncbi.nlm.nih.gov/18971388
Autor:
Toshio Matsuda, Hoa Dinh Le, Gil J. Gross, Larry V. Hryshko, Akemichi Baba, Alexander Omelchenko, Platon Choptiany, Candace Lee, Kenzo Takahashi, Neeraj Visen, Naranjan S. Dhalla, Michael R. Isaac, Mark Hnatowich
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 311(2)
SEA0400 (2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline) has recently been described as a potent and selective inhibitor of Na(+)-Ca(2+) exchange in cardiac, neuronal, and renal preparations. The inhibitory effects of SEA0400 were investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53eee985f8c2578b6e6b58296a109d7
https://pubmed.ncbi.nlm.nih.gov/15231867
https://pubmed.ncbi.nlm.nih.gov/15231867
Autor:
Christian R. Marshall, Alexander Omelchenko, Xiao-Hua Xue, Chadwick L. Elias, Glen F. Tibbits, Hoa Dinh Le, Larry V. Hryshko
Publikováno v:
Annals of the New York Academy of Sciences. 976
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fd6933b1052a0c0d9cd4cfc65b8e6d
https://pubmed.ncbi.nlm.nih.gov/12502547
https://pubmed.ncbi.nlm.nih.gov/12502547