Zobrazeno 1 - 10
of 10
pro vyhledávání: '"HoMan Chan"'
Autor:
Frank Stegmeier, Michael R. Schlabach, Junxia Min, Yi Yang, HoMan Chan, Veronica Gibaja, Michelle Lira, Iris Kao, Daniel Rakiec, David Ruddy, Adnan Derti, Qianhe Zhou
Supplemental Table 3: List of alternatively spliced genes identified in response to SF3B1 mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a18bb0f8d4724ecc90c7877a1b662da
https://doi.org/10.1158/0008-5472.22405301.v1
https://doi.org/10.1158/0008-5472.22405301.v1
Autor:
Min Hu, Yan Wang, En Li, Peter Atadja, Chris Lu, Homan Chan, Xu Wu, Jun Liu, Jing Wu, Qian Li, Shaolian Zhou, Wei Yi, Jingquan Dai, Yanyan Yu, Kehao Zhao, Teddy Yang, Man Zhang, Justin Gu, Youzhen Wang, Ming Fang, Hailong Zhang, Zhaofu Wang, Nathan Englund, Feng Yan, Fiona Xu, Shannon Chuai, Haiping Wu, Zheng Huang
XLSX file, 863K, Lists of differentially expressed genes (DEGs) from comparisons of PAR_TKO and active_inactive groups and overlapping DEGs (p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cb8a2cc9b8b5e2f8378efd90c1d1eb
https://doi.org/10.1158/0008-5472.22396584
https://doi.org/10.1158/0008-5472.22396584
Autor:
Min Hu, Yan Wang, En Li, Peter Atadja, Chris Lu, Homan Chan, Xu Wu, Jun Liu, Jing Wu, Qian Li, Shaolian Zhou, Wei Yi, Jingquan Dai, Yanyan Yu, Kehao Zhao, Teddy Yang, Man Zhang, Justin Gu, Youzhen Wang, Ming Fang, Hailong Zhang, Zhaofu Wang, Nathan Englund, Feng Yan, Fiona Xu, Shannon Chuai, Haiping Wu, Zheng Huang
XLSX file, 450K, Gene set enrichment analysis (GSEA) reports for comparisons of PAR_TKO and active_inactive groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9de81b1e18ce1e9883e61c152e7bb18
https://doi.org/10.1158/0008-5472.22396581
https://doi.org/10.1158/0008-5472.22396581
Autor:
Frank Stegmeier, Michael R. Schlabach, Junxia Min, Yi Yang, HoMan Chan, Veronica Gibaja, Michelle Lira, Iris Kao, Daniel Rakiec, David Ruddy, Adnan Derti, Qianhe Zhou
Assessing the functional significance of novel putative oncogenes remains a significant challenge given the limitations of current loss-of-function tools. Here, we describe a method that employs TALEN or CRISPR/Cas9-mediated knock-in of inducible deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458b45e418d201e1017b53be47f0dfae
https://doi.org/10.1158/0008-5472.c.6506798
https://doi.org/10.1158/0008-5472.c.6506798
Autor:
Min Hu, Yan Wang, En Li, Peter Atadja, Chris Lu, Homan Chan, Xu Wu, Jun Liu, Jing Wu, Qian Li, Shaolian Zhou, Wei Yi, Jingquan Dai, Yanyan Yu, Kehao Zhao, Teddy Yang, Man Zhang, Justin Gu, Youzhen Wang, Ming Fang, Hailong Zhang, Zhaofu Wang, Nathan Englund, Feng Yan, Fiona Xu, Shannon Chuai, Haiping Wu, Zheng Huang
PDF file, 153K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8e747f14e77fc2773ba97bb7d99700
https://doi.org/10.1158/0008-5472.22396590.v1
https://doi.org/10.1158/0008-5472.22396590.v1
Autor:
Frank Stegmeier, Michael R. Schlabach, Junxia Min, Yi Yang, HoMan Chan, Veronica Gibaja, Michelle Lira, Iris Kao, Daniel Rakiec, David Ruddy, Adnan Derti, Qianhe Zhou
Supplemental Figure 1. Efficient knock�in of DD�domain into the endogenous p53 locus by TALENs in HCT116 cells. Supplemental Figure 2. PCR verification of Degron�KI clones. Supplemental Figure 3. Immunofluorescence staining of De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b300a710390d54707412a6f01d0556b
https://doi.org/10.1158/0008-5472.22405304.v1
https://doi.org/10.1158/0008-5472.22405304.v1
Autor:
Min Hu, Yan Wang, En Li, Peter Atadja, Chris Lu, Homan Chan, Xu Wu, Jun Liu, Jing Wu, Qian Li, Shaolian Zhou, Wei Yi, Jingquan Dai, Yanyan Yu, Kehao Zhao, Teddy Yang, Man Zhang, Justin Gu, Youzhen Wang, Ming Fang, Hailong Zhang, Zhaofu Wang, Nathan Englund, Feng Yan, Fiona Xu, Shannon Chuai, Haiping Wu, Zheng Huang
PDF file, 989K, Depletion of NSD2 has only mild effects on myeloma cell proliferation. Supplementary Figure S2. NSD2 is important for tumorigenesis of t(4;14)+ myeloma cells. Supplementary Figure S3. PHD domains are important for cellular H3K36me2 ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fba6655f94ec2d8271115d3f32fdee2
https://doi.org/10.1158/0008-5472.22396593.v1
https://doi.org/10.1158/0008-5472.22396593.v1
Autor:
Min Hu, Yan Wang, En Li, Peter Atadja, Chris Lu, Homan Chan, Xu Wu, Jun Liu, Jing Wu, Qian Li, Shaolian Zhou, Wei Yi, Jingquan Dai, Yanyan Yu, Kehao Zhao, Teddy Yang, Man Zhang, Justin Gu, Youzhen Wang, Ming Fang, Hailong Zhang, Zhaofu Wang, Nathan Englund, Feng Yan, Fiona Xu, Shannon Chuai, Haiping Wu, Zheng Huang
Histone lysine methyltransferase NSD2 (WHSC1/MMSET) is overexpressed frequently in multiple myeloma due to the t(4;14) translocation associated with 15% to 20% of cases of this disease. NSD2 has been found to be involved in myelomagenesis, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b021285e04af7c6b81bdd5d3bfff4353
https://doi.org/10.1158/0008-5472.c.6504609.v1
https://doi.org/10.1158/0008-5472.c.6504609.v1
Publikováno v:
EMBO reports. 8:952-958
The multidomain-containing cellular protein BS69 interacts with adenovirus E1A and several other viral and cellular factors, and acts as a transcription repressor. Here, we show that BS69 is involved in the p53-p21Cip1-mediated senescence pathway. Kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166cc42b7616c156646cb4e12d5ee79d
https://doi.org/10.1038/sj.embor.7401049
https://doi.org/10.1038/sj.embor.7401049
Autor:
Jacob Jaffe, Yan Wang, HoMan Chan, Jinghui Zhang, Roberts Huether, Gregory Kryukov, Jordan Taylor, Min Hu, Nathan Englund, Feng Yan, Zhaofu Wang, Lei Wei, Jing Ma, John Easton, William R. Sellers, Nicholas Keen, Jun Liu, Charles Mullighan, Steven Carr, James Downing, Levi Garraway, Frank Stegmeier
Publikováno v:
Cancer Research. 73:PR01-PR01
Epigenetic dysregulation is an emerging hallmark of cancers, and the identification of recurrent somatic mutations in chromatin modifying enzymes implies a causal role for altered chromatin states in tumorigenesis. While the genomic characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d389724640f69401a06aadddb7e8e43b
https://doi.org/10.1158/1538-7445.cec13-pr01
https://doi.org/10.1158/1538-7445.cec13-pr01