Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ho-pi Lin"'
Autor:
Kimberly Raines, Kaushalkumar Dave, Banu S. Zolnik, Hansong Chen, Ho-Pi Lin, Ge Bai, Zhijin Chen
Publikováno v:
Journal of Pharmaceutical Innovation. 15:547-555
The concept of quality by design (QbD) was introduced to the pharmaceutical industry about a decade ago. Design of experiments (DoE) is an excellent and important tool for a QbD approach. This project’s aim is to obtain an overview of how DoE is be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed5d69ce06d0c4fcf5dab5d1843cdea
https://doi.org/10.1007/s12247-019-09400-9
https://doi.org/10.1007/s12247-019-09400-9
Autor:
Ping Zhao, Lawrence X. Yu, Paul Seo, Ho-Pi Lin, Yang Zhao, Heta Shah, Min Li, Fang Wu, S Suarez, Kimberly Raines, John Duan, Peng Duan, Meng Wang
Publikováno v:
The AAPS journal. 23(2)
Physiologically based pharmacokinetic (PBPK) absorption modeling and simulation is increasingly used as a tool in drug product development, not only in support of clinical pharmacology applications (e.g., drug-drug interaction, dose selection) but al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e69997c783778b6a7feb1bd4bbc2c0
https://pubmed.ncbi.nlm.nih.gov/33619657
https://pubmed.ncbi.nlm.nih.gov/33619657
Autor:
Ho-Pi Lin, Tycho Heimbach, Paul Seo, Min Li, Xinyuan Zhang, Maziar Kakhi, Xavier Pepin, Andrés Olivares-Morales, Denise Morris, Sandra Suarez-Sharp, Filippos Kesisoglou, Nikunjkumar Patel, Eleftheria Tsakalozou, Amitava Mitra, Nico Holmstock, Erik Sjögren, Timothy H. Montague
Publikováno v:
The AAPS Journal. 21
This publication summarizes the proceedings of day 2 of a 3-day workshop on "Dissolution and Translational Modeling Strategies Enabling Patient-Centric Product Development." Patient-centric drug product development from a drug product quality perspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ecfb60d168ca2769f3dcb2195316055
https://doi.org/10.1208/s12248-019-0298-x
https://doi.org/10.1208/s12248-019-0298-x
Publikováno v:
Journal of pharmaceutical sciences. 105(10)
A Food and Drug Administration-approved generic oral product of venlafaxine hydrochloride (HCl) extended-release (ER) tablets has used a release mechanism based on an openable matrix, which is different from the push-pull osmotic pump system of its r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04925d7889f4167f215260726771e3fe
https://pubmed.ncbi.nlm.nih.gov/27449228
https://pubmed.ncbi.nlm.nih.gov/27449228
Publikováno v:
Biology of the Cell
Background information. Cell fusion is known to underlie key developmental processes in humans and is postulated to contribute to tissue maintenance and even carcinogenesis. The mechanistic details of cell fusion, especially between different cell ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f4c9909a640925b3ce0adb1e5be5a0
http://europepmc.org/articles/PMC2917994
http://europepmc.org/articles/PMC2917994
Autor:
Victor E. Marquez, Jiuxiang Zhu, Ching Shih Chen, Ho-Pi Lin, Donn C. Young, Xueqin Song, Shunqi Yan
Publikováno v:
CancerSpectrum Knowledge Environment. 94:1745-1757
Background: The cyclooxygenase-2 (COX-2) inhibitor celecoxib is thought to act as a chemopreventive agent by sensitizing cancer cells to apoptotic signals. Other COX-2 inhibitors, such as rofecoxib, are two orders of magnitude less potent than celeco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16510d722df0b8e55b8ffb3d1dbdd813
https://doi.org/10.1093/jnci/94.23.1745
https://doi.org/10.1093/jnci/94.23.1745
Autor:
Nelson Arispe, Ho-pi Lin
Publikováno v:
Cell stresschaperones. 20(2)
Interaction of the Alzheimer's Aβ peptides with the plasma membrane of cells in culture results in chronic increases in cytosolic [Ca(2+)]. Such increases can cause a variety of secondary effects leading to impaired cell growth or cell degeneration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3855f24a3c991a5bbf02cb4e59de20e
https://pubmed.ncbi.nlm.nih.gov/25366568
https://pubmed.ncbi.nlm.nih.gov/25366568
Autor:
Tsui Ting Ching, Marcos A. Oliveira, Ching Shih Chen, Chih Cheng Yang, Ho Pi Lin, Pei Jung Lu
Publikováno v:
Journal of Biological Chemistry. 276:43932-43938
Phosphoinositide second messengers, generated from the action of phosphoinositide 3-kinase (PI3K), mediate an array of signaling pathways through the membrane recruitment and activation of downstream effector proteins. Although pleckstrin domains of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a687b0a08cc11232fdd27e72f4f87d58
https://doi.org/10.1074/jbc.m105159200
https://doi.org/10.1074/jbc.m105159200
Autor:
Wan-Jr Syu, Bo-Shiun Yan, I-Jane Sheen, Chen-Kung Chou, Sheng-Chieh Hsu, Ho-Pi Lin, Kai-Liang Ko, Jaw Ching Wu
Publikováno v:
Journal of Virological Methods. 87:53-62
Sequences of the hepatitis delta virus (HDV) vary to different degrees among isolates. A monoclonal antibody, designated as HP6A1, against the antigen of HDV (HDAg) has been characterized for its specificity. HP6A1 bound to HDAg of isolate 25 (genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a7d52e6436f30939545c9999863218
https://doi.org/10.1016/s0166-0934(00)00147-6
https://doi.org/10.1016/s0166-0934(00)00147-6