Zobrazeno 1 - 10
of 436
pro vyhledávání: '"Ho-Keung Ng"'
Autor:
Iram Shazia Tyagi, Ho Yin Calvin Tsui, Si Chen, Xinyi Li, Wai-Kin Mat, Muhammad A. Khan, Lucas Brendan Choy, Ka-Yin Aden Chan, Tat-Ming Danny Chan, Chi-Ping Stephanie Ng, Ho-Keung Ng, Wai Sang Poon, Hong Xue
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Introduction Anti-mitosis has been a key strategy of anti-cancer therapies, targeting at a fundamental property of cancer cells, their non-controllable proliferation due to overactive mitotic divisions. For improved anti-cancer therapies, it
Externí odkaz:
https://doaj.org/article/07f3251a2fde49b0933710dbc4ed1c16
Autor:
Zhi-Feng Shi, Kay Ka-Wai Li, Anthony Pak-Yin Liu, Nellie Yuk-Fei Chung, Sze-Ching Wong, Hong Chen, Peter Yat-Ming Woo, Danny Tat-Ming Chan, Ying Mao, Ho-Keung Ng
Publikováno v:
Cancers, Vol 16, Iss 9, p 1740 (2024)
Pediatric brain tumors are often noted to be different from their adult counterparts in terms of molecular features. Primary CNS lymphomas (PCNSLs) are mostly found in elderly adults and are uncommon in children and teenagers. There has only been sca
Externí odkaz:
https://doaj.org/article/f40ac6f5bbf349a683e5e887e69871c3
Autor:
Zhi-Feng Shi, Kay Ka-Wai Li, Anthony Pak-Yin Liu, Nellie Yuk-Fei Chung, Chit Chow, Hong Chen, Nim-Chi Amanda Kan, Xian-Lun Zhu, Danny Tat-Ming Chan, Ying Mao, Ho-Keung Ng
Publikováno v:
Cancers, Vol 16, Iss 1, p 232 (2024)
Pediatric high-grade gliomas (HGG) of the cerebellum are rare, and only a few cases have been documented in detail in the literature. A major differential diagnosis for poorly differentiated tumors in the cerebellum in children is medulloblastoma. In
Externí odkaz:
https://doaj.org/article/10326b73299b47a7ae1933afa038a153
Autor:
Otto C. H. Tam, Ronnie S. L. Ho, Shing Chan, Kay K. W. Li, Tit-Leung Lam, Elaine T. Y. Cheung, Oi-Yee Cheung, Wilson W. S. Ho, Kevin K. F. Cheng, Matthew M. K. Shing, Dennis T. L. Ku, Brian H. Y. Chung, Wanling Yang, Godfrey C. F. Chan, Ho-Keung Ng, Anthony P. Y. Liu
Publikováno v:
Cancers, Vol 15, Iss 19, p 4880 (2023)
This paper examines the link between CNS tumor biology and heterogeneity and the use of genome-wide DNA methylation profiling as a clinical diagnostic platform. CNS tumors are the most common solid tumors in children, and their prognosis remains poor
Externí odkaz:
https://doaj.org/article/5abe8a8d8b3742e38da70e8c545258a7
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 21, Iss 9, Pp 705-709 (2021)
doi:10.3969/j.issn.1672⁃6731.2021.09.001
Externí odkaz:
https://doaj.org/article/561e6fa22e934a34ba0c4a49709ca7e4
Autor:
Patryk Skowron, Hamza Farooq, Florence M. G. Cavalli, A. Sorana Morrissy, Michelle Ly, Liam D. Hendrikse, Evan Y. Wang, Haig Djambazian, Helen Zhu, Karen L. Mungall, Quang M. Trinh, Tina Zheng, Shizhong Dai, Ana S. Guerreiro Stucklin, Maria C. Vladoiu, Vernon Fong, Borja L. Holgado, Carolina Nor, Xiaochong Wu, Diala Abd-Rabbo, Pierre Bérubé, Yu Chang Wang, Betty Luu, Raul A. Suarez, Avesta Rastan, Aaron H. Gillmor, John J. Y. Lee, Xiao Yun Zhang, Craig Daniels, Peter Dirks, David Malkin, Eric Bouffet, Uri Tabori, James Loukides, François P. Doz, Franck Bourdeaut, Olivier O. Delattre, Julien Masliah-Planchon, Olivier Ayrault, Seung-Ki Kim, David Meyronet, Wieslawa A. Grajkowska, Carlos G. Carlotti, Carmen de Torres, Jaume Mora, Charles G. Eberhart, Erwin G. Van Meir, Toshihiro Kumabe, Pim J. French, Johan M. Kros, Nada Jabado, Boleslaw Lach, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, James M. Olson, László Bognár, Almos Klekner, Karel Zitterbart, Joanna J. Phillips, Reid C. Thompson, Michael K. Cooper, Joshua B. Rubin, Linda M. Liau, Miklós Garami, Peter Hauser, Kay Ka Wai Li, Ho-Keung Ng, Wai Sang Poon, G. Yancey Gillespie, Jennifer A. Chan, Shin Jung, Roger E. McLendon, Eric M. Thompson, David Zagzag, Rajeev Vibhakar, Young Shin Ra, Maria Luisa Garre, Ulrich Schüller, Tomoko Shofuda, Claudia C. Faria, Enrique López-Aguilar, Gelareh Zadeh, Chi-Chung Hui, Vijay Ramaswamy, Swneke D. Bailey, Steven J. Jones, Andrew J. Mungall, Richard A. Moore, John A. Calarco, Lincoln D. Stein, Gary D. Bader, Jüri Reimand, Jiannis Ragoussis, William A. Weiss, Marco A. Marra, Hiromichi Suzuki, Michael D. Taylor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Sonic Hedgehog medulloblastoma (Shh-MB) comprises four subtypes each with distinct clinical traits. Here the authors characterize the genome, transcriptome, and methylome of Shh-MB subtypes, revealing a complex fusion landscape and the molecular conv
Externí odkaz:
https://doaj.org/article/091429a4162845e7a18371f487596c6f
Autor:
Anthony P. Y. Liu, Qi Liu, Matthew M. K. Shing, Dennis T. L. Ku, Eric Fu, Chung-Wing Luk, Siu-Cheung Ling, Kevin K. F. Cheng, Dora L. W. Kwong, Wilson W. S. Ho, Ho-Keung Ng, Amar Gajjar, Yutaka Yasui, Godfrey C. F. Chan, Gregory T. Armstrong
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 704-721 (2020)
PURPOSE Despite being the most common pediatric solid tumors, incidence and outcome of CNS tumors in Chinese children have not been systematically reported. We addressed this knowledge gap by comparing the epidemiology of pediatric CNS tumors in Hong
Externí odkaz:
https://doaj.org/article/c005d0a9f6ca4072a98e35fc9a5f7ad6
Autor:
Gabriel Chun-Hei Wong, Kay Ka-Wai Li, Wei-Wei Wang, Anthony Pak-Yin Liu, Queenie Junqi Huang, Aden Ka-Yin Chan, Manix Fung-Man Poon, Nellie Yuk-Fei Chung, Queenie Hoi-Wing Wong, Hong Chen, Danny Tat Ming Chan, Xian-Zhi Liu, Ying Mao, Zhen-Yu Zhang, Zhi-Feng Shi, Ho-Keung Ng
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)
Abstract Adult medulloblastomas are clinically and molecularly understudied due to their rarity. We performed molecular grouping, targeted sequencing, and TERT promoter Sanger sequencing on a cohort of 99 adult medulloblastomas. SHH made up 50% of th
Externí odkaz:
https://doaj.org/article/e23ed8382f864108a4c0b654e679d523
Autor:
Aden Ka-Yin Chan, Zhi-Feng Shi, Kay Ka-Wai Li, Wei-Wei Wang, Hong Chen, Nellie Yuk-Fei Chung, Danny Tat-Ming Chan, Wai-Sang Poon, Herbert Ho-fung Loong, Xian-Zhi Liu, Zhen-Yu Zhang, Ying Mao, Ho-Keung Ng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Advanced genomic techniques have now been incorporated into diagnostic practice in neuro-oncology in the literature. However, these assays are expensive and time-consuming and demand bioinformatics expertise for data interpretation. In contrast, sing
Externí odkaz:
https://doaj.org/article/b53c1e2d27554d8a9b60b8ab409844eb
Publikováno v:
Glioma, Vol 3, Iss 3, Pp 135-142 (2020)
Background and Aim: Glioblastoma (GBM) is the most common and aggressive form of primary malignant brain tumors. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta (PIK3CD), which is overexpressed in GBM, is involved in GBM pathog
Externí odkaz:
https://doaj.org/article/40c6f5fcdd3c48288feb86b16719dc72