Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ho-June Lee"'
Autor:
Hyunjoo Kim, Muhah Jeong, Do-Hyeong Na, Shin-Hyeon Ryu, Eun Il Jeong, Kwangmin Jung, Jaemin Kang, Ho-June Lee, Taebo Sim, Dae-Yeul Yu, Hee Chul Yu, Baik-Hwan Cho, Yong-Keun Jung
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-11 (2022)
Abstract The RAS–BRAF signaling is a major pathway of cell proliferation and their mutations are frequently found in human cancers. Adenylate kinase 2 (AK2), which modulates balance of adenine nucleotide pool, has been implicated in cell death and
Externí odkaz:
https://doaj.org/article/fb10c0acc0f142279e3ed6c60c4718e7
Autor:
Anwesha Dey, Matthew T. Chang, Shiva Malek, Christiaan Klijn, Jennie R. Lill, Zora Modrusan, Victoria C. Pham, Deepak Sampath, Jennifer A. Lacap, Robert Piskol, Scott E. Martin, Mamie Yu, Eva Lin, Christopher M. Rose, Jason Li, Ho-June Lee, Thijs J. Hagenbeek, Trang H. Pham
Gene signature correlations with clusters 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc5a509d6d7ee921c61c84db2e4106c
https://doi.org/10.1158/2159-8290.22536533.v1
https://doi.org/10.1158/2159-8290.22536533.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 25K, Pharmacokinetic parameters of PKC412.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142f3edab434901c372ae690791ad537
https://doi.org/10.1158/2159-8290.22528442
https://doi.org/10.1158/2159-8290.22528442
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 528K, G�6976 inhibits EGFR mutant NSCLC cells independently of PKC inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d214e502c85c2ea75045588a3cbaf18c
https://doi.org/10.1158/2159-8290.22528460
https://doi.org/10.1158/2159-8290.22528460
Autor:
Anwesha Dey, Matthew T. Chang, Shiva Malek, Christiaan Klijn, Jennie R. Lill, Zora Modrusan, Victoria C. Pham, Deepak Sampath, Jennifer A. Lacap, Robert Piskol, Scott E. Martin, Mamie Yu, Eva Lin, Christopher M. Rose, Jason Li, Ho-June Lee, Thijs J. Hagenbeek, Trang H. Pham
Supplementary Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df980ef656b2ba535dfad88f19c5f58
https://doi.org/10.1158/2159-8290.22536551.v1
https://doi.org/10.1158/2159-8290.22536551.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 142K, EGFR sequencing of the PC-9 ER clone.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b393712033171d96340c02807f748c6f
https://doi.org/10.1158/2159-8290.22528451.v1
https://doi.org/10.1158/2159-8290.22528451.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 21K, Body weight measurement for EGFR T790M xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63abfacbcb1b8fee04af011cb0b6c75
https://doi.org/10.1158/2159-8290.22528445
https://doi.org/10.1158/2159-8290.22528445
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
XLSX file - 242K, Ambit kinome profiling with 0.5 μM G�6976.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123fe209a3a1b72e9490e71f54d25c84
https://doi.org/10.1158/2159-8290.22528463.v1
https://doi.org/10.1158/2159-8290.22528463.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 28K, PKC412 is the most selective EGFR T790M inhibitor tested versus EGFR wild-type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ce89850a6f9e97571d24972b77a5f5
https://doi.org/10.1158/2159-8290.22528457
https://doi.org/10.1158/2159-8290.22528457
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
Approximately half of EGFR-mutant non–small cell lung cancer (NSCLC) patients treated with small-molecule EGFR kinase inhibitors develop drug resistance associated with the EGF receptor (EGFR) T790M “gatekeeper” substitution, prompting efforts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d720cf951858302908773bbba810a80
https://doi.org/10.1158/2159-8290.c.6545714.v1
https://doi.org/10.1158/2159-8290.c.6545714.v1