Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ho-Chang Jeong"'
Autor:
Seung-Ju Cho, Keun-Tae Kim, Ho-Chang Jeong, Ju-Chan Park, Ok-Seon Kwon, Yun-Ho Song, Joong-Gon Shin, Seungmin Kang, Wankyu Kim, Hyoung Doo Shin, Mi-Ok Lee, Sung-Hwan Moon, Hyuk-Jin Cha
Publikováno v:
Stem Cell Reports, Vol 11, Iss 5, Pp 1244-1256 (2018)
Summary: The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a serious safety concern for their clinical application. With a set of hESCs with various passage numbers, we observed that a subpopulation of hESCs at
Externí odkaz:
https://doaj.org/article/592605e5a71c47feab63b767afa74cf0
Autor:
Young-Hyun Go, Changjin Lim, Ho-Chang Jeong, Ok-Seon Kwon, Sungkyun Chung, Haeseung Lee, Wankyu Kim, Young-Ger Suh, Woo Sung Son, Mi-Ok Lee, Hyuk-Jin Cha, Seok-Ho Kim
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Despite great potential for regenerative medicine, the high tumorigenic potential of human pluripotent stem cells (hPSCs) to form undesirable teratoma is an important technical hurdle preventing safe cell therapy. Various small molecules that induce
Externí odkaz:
https://doaj.org/article/6494ba0c258f42d4b5b4cbe7dc525f06
Autor:
Seung-Ju Cho, So-Yeon Kim, Ho-Chang Jeong, Hyeonsik Cheong, Doseok Kim, Soon-Jung Park, Jong-Jin Choi, Hyongbum Kim, Hyung-Min Chung, Sung-Hwan Moon, Hyuk-Jin Cha
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1067-1080 (2015)
Stem-toxic small molecules have been developed to induce selective cell death of pluripotent stem cells (PSCs) to lower the risk of teratoma formation. However, despite their high efficacies, chemical-based approaches may carry unexpected toxicities
Externí odkaz:
https://doaj.org/article/ca32e091591740c0b2435fffaa5cba46
Autor:
Young-Hyun Go, Jumee Kim, Ho-Chang Jeong, Seong-Min Kim, Yun-Jeong Kim, Soon-Jung Park, Sung-Hwan Moon, Hyuk-Jin Cha
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 453 (2020)
Despite recent advances in clinical stem cell therapy applications based on human pluripotent stem cells (hPSCs), potential teratoma formation due to the presence of residual undifferentiated hPSCs remains a serious risk factor that challenges widesp
Externí odkaz:
https://doaj.org/article/b5d25e69ae8f4b0f943437fe559a091c
Autor:
Young-Hyun Go, Hyo-Ju Lee, Hyeon-Joon Kong, Ho-Chang Jeong, Dong Young Lee, Soon-Ki Hong, Sang Hyun Sung, Ok-Seon Kwon, Hyuk-Jin Cha
Publikováno v:
Royal Society Open Science, Vol 5, Iss 12 (2018)
The Fluorescent Ubiquitination-based Cell Cycle Indicator (FUCCI) system can be used not only to study gene expression at a specific cell cycle stage, but also to monitor cell cycle transitions in real time. In this study, we used a single clone of F
Externí odkaz:
https://doaj.org/article/73015de21a2a450c8ff0cd08a0c04f00
Autor:
Ho-Chang Jeong1,2, Shukla, Siddharth3,4, Fok, Wilson Chun1,2, Huynh, Thao Ngoc3,4, Batista, Luis Francisco Zirnberger1,2 lbatista@wustl.edu, Parker, Roy3,4 roy.parker@colorado.edu
Publikováno v:
Science. 3/3/2023, Vol. 379 Issue 6635, p901-907. 7p. 4 Diagrams.
Autor:
Yun-Jeong Kim, Young-Hyun Go, Ho-Chang Jeong, Eun-Ji Kwon, Seong-Min Kim, Hyun Sub Cheong, Wantae Kim, Hyoung Doo Shin, Haeseung Lee, Hyuk-Jin Cha
Publikováno v:
Experimental & Molecular Medicine. 55:32-42
Genetic alterations have been reported for decades in most human embryonic stem cells (hESCs). Survival advantage, a typical trait acquired during long-term in vitro culture, results from the induction of BCL2L1 upon frequent copy number variation (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a924e83a78ccf2ab3545de0342a4aa
https://doi.org/10.1038/s12276-022-00907-9
https://doi.org/10.1038/s12276-022-00907-9
Autor:
Lee, Jiho, Ho Chang, Jeong
Publikováno v:
In Journal of Solid State Chemistry April 2012 188:100-104
Publikováno v:
Blood Adv
Dyskeratosis congenita (DC) is a pediatric bone marrow failure syndrome caused by germline mutations in telomere biology genes. Mutations in DKC1 (the most commonly mutated gene in DC), the 3′ region of TERC, and poly(A)-specific ribonuclease (PARN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3b09106db1d20883f517f30c5e187d
https://doi.org/10.1182/bloodadvances.2020001848
https://doi.org/10.1182/bloodadvances.2020001848
Autor:
Ho-Chang Jeong, Young-Hyun Go, Joong-Gon Shin, Yun-Jeong Kim, Min-Guk Cho, Dasom Gwon, Hyun Sub Cheong, Haeseung Lee, Jae-Ho Lee, Chang-Young Jang, Hyoung Doo Shin, Hyuk-Jin Cha
Despite highly effective machinery for the maintenance of genome integrity in human embryonic stem cells (hESCs), the frequency of genetic aberrations during in-vitro culture has been a serious issue for future clinical applications. By passaging hES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa428e3f14b8b0fb8ec648966bbf63a
https://doi.org/10.21203/rs.3.rs-982680/v1
https://doi.org/10.21203/rs.3.rs-982680/v1
