Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ho Yeon Nam"'
Autor:
Minsang Kim, Yeongmi Cheon, Dongmin Shin, Jieun Choi, Josefine Eilsø Nielsen, Myeong Seon Jeong, Ho Yeon Nam, Sung‐Hak Kim, Reidar Lund, Håvard Jenssen, Annelise E. Barron, Seongsoo Lee, Jiwon Seo
Publikováno v:
Advanced Science, Vol 10, Iss 24, Pp n/a-n/a (2023)
Abstract Antimicrobial peptides (AMPs) are promising therapeutics in the fight against multidrug‐resistant bacteria. As a mimic of AMPs, peptoids with N‐substituted glycine backbone have been utilized for antimicrobials with resistance against pr
Externí odkaz:
https://doaj.org/article/b83c343184e24617b1e454cf97703cb1
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 87:129259
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908b17026120ffd679af6cae84db58e2
https://doi.org/10.1016/j.bmcl.2023.129259
https://doi.org/10.1016/j.bmcl.2023.129259
Autor:
Dahyun Kang, Jiwon Seo, Minkyu Kyeong, Sungrok Wang, Håvard Jenssen, Josefine Eilsø Nielsen, Reidar Lund, Jiyoun Lee, Yunjee Lee, S. Dinesh Kumar, Myung-Han Yoon, Song Yub Shin, Jieun Choi, Sukwon Hong, Ho Yeon Nam
Publikováno v:
ACS Infectious Diseases. 6:2732-2744
The modulation of conformational flexibility in antimicrobial peptides (AMPs) has been investigated as a strategy to improve their efficacy against bacterial pathogens while reducing their toxicity. Here, we synthesized a library of helicity-modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae5d59881478d4c4599f40cb6b05ee4
https://doi.org/10.1021/acsinfecdis.0c00356
https://doi.org/10.1021/acsinfecdis.0c00356
Autor:
Kyung Tae Hong, Jiyoun Lee, Jong-Ah Hong, Dasom Song, Na-Eun Choi, Jiwon Seo, Jun-Seok Lee, Jinny Eo, Ho Yeon Nam
Publikováno v:
ACS Chemical Biology. 15:2346-2354
The high temperature requirement A (HTRA) family of serine proteases mediates protein quality control. These proteins process misfolded proteins in several diseases including Alzheimer's disease (AD) and Parkinson's disease (PD). While their structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413a5077009a8a499fe96be95526d102
https://doi.org/10.1021/acschembio.0c00279
https://doi.org/10.1021/acschembio.0c00279
Publikováno v:
Peptide Science. 114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f76d0e498b36dfb2c98b0ece6a86b6d1
https://doi.org/10.1002/pep2.24239
https://doi.org/10.1002/pep2.24239
Publikováno v:
Biochemistry. 59:270-284
Mitochondria are multifunctional subcellular organelles whose operations encompass energy production, signal transduction, and metabolic regulation. Given their wide range of roles, they have been studied extensively as a potential therapeutic target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727ce210c5761b1e4464fd1aa50f97d7
https://doi.org/10.1021/acs.biochem.9b00857
https://doi.org/10.1021/acs.biochem.9b00857
Publikováno v:
Analytical Chemistry. 91:13772-13779
Most prevalent infectious diseases worldwide are caused by mediators such as insects and characterized by high mortality and morbidity, thereby creating a global public health concern. Therefore, a sensitive, selective detection platform for diagnosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fa09a582b129924bfead4bc9c0b535
https://doi.org/10.1021/acs.analchem.9b03210
https://doi.org/10.1021/acs.analchem.9b03210
Publikováno v:
Bioconjugate chemistry. 29(5)
Mitochondria-specific delivery methods offer a valuable tool for studying mitochondria-related diseases and provide breakthroughs in therapeutic development. Although several small-molecule and peptide-based transporters have been developed, peptoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfedf2c0ff1c66f7aa73e7ce433757e
https://pubmed.ncbi.nlm.nih.gov/29578690
https://pubmed.ncbi.nlm.nih.gov/29578690
Publikováno v:
Organicbiomolecular chemistry. 15(38)
We developed a smart activity-based probe that detects the activity of asparaginyl endopeptidase (AEP) in live cells to monitor the dynamics of enzyme regulation. The newly designed probe generated a turn-on fluorescence signal in response to the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffa4b7886caffce0e9a5c88d364aadb
https://pubmed.ncbi.nlm.nih.gov/28920116
https://pubmed.ncbi.nlm.nih.gov/28920116
Autor:
Ho Yeon Nam, Jieun Choi, Kumar, S. Dinesh, Nielsen, Josefine Eilsø, Minkyu Kyeong, Sungrok Wang, Dahyun Kang, Yunjee Lee, Jiyoun Lee, Myung-Han Yoon, Sukwon Hong, Lund, Reidar, Jenssen, Håvard, Song Yub Shin, Jiwon Seo
Publikováno v:
ACS Infectious Diseases; 10/9/2020, Vol. 6 Issue 10, p2732-2744, 13p