Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ho Taek Im"'
Publikováno v:
Inflammation. 42(1)
Bupleurum falcatum (Umbelliferae) have been widely used to treat inflammatory diseases as traditional medicines in East Asian region. Although saikosaponins are main bioactive molecules of B. falcatum, there is little information on bioactivity of sa
Autor:
Jong-Heon Won1, Ho-Taek Im1, Yang-Hee Kim1, Kyung-Jin Yun1, Hee-Juhn Park2, Jong-Won Choi3, Kyung-Tae Lee1 ktlee@khu.ac.kr
Publikováno v:
British Journal of Pharmacology. May2006, Vol. 148 Issue 2, p216-225. 10p. 1 Diagram, 4 Graphs.
Autor:
Srinivasan Shanmugam, Yong-Il Kim, Young-Hun Kim, Ho Taek Im, Jong Oh Kim, Jong Soo Woo, Jeong-Hee Park, Kyeong Soo Kim, Chul Soon Yong, Young Taek Sohn, Han-Gon Choi
Publikováno v:
Drug Development and Industrial Pharmacy. 40:803-812
The main objective was to investigate the in vitro release profile/kinetics, and in vivo plasma pharmacokinetics (PK) and organ biodistribution (BD) of the prepared sildenafil vaginal suppositories (SVS).Suppositories containing 25 mg of sildenafil w
Autor:
Ho Taek Im, Yong-Il Kim, Young Taek Sohn, Jong Soo Woo, Han-Gon Choi, Jong Oh Kim, Srinivasan Shanmugam, Chul Soon Yong, Kyung Soo Kim
Publikováno v:
Biomolecules & Therapeutics
The objective of this study was to enhance the oral bioavailability (BA) of zanamivir (ZMR) by increasing its intestinal permeability using permeation enhancers (PE). Four different classes of PEs (Labrasol(®), sodium cholate, sodium caprate, hydrox
Autor:
Hyun-Su Lee, Ho-Taek Im, Jong-Bin Kim, Sung-Hee Cho, Il-Mo Kang, Heon-Woo Lee, Sung-Su Kim, Kyung-Tae Lee
Publikováno v:
Journal of Chromatography B. 852:174-179
A sensitive and accurate HPLC-UV method for the quantification of fluconazole (FLA) level in human plasma has been developed. The sample was prepared by one-step liquid-liquid extraction (LLE) of FLA from plasma using dichloromethane. Phenacetin was
Autor:
Jong Soo Woo, Yong-Il Kim, Eun-Seok Park, Ho Taek Im, Young Taek Sohn, Srinivasan Shanmugam, Jae-Hyun Park
Publikováno v:
Drug development and industrial pharmacy. 41(11)
The main objective of this study was to develop novel orally administrable tablets containing solid dispersion granules (SDG) of amorphous paclitaxel (PTX) prepared by fluid bed technology, and to evaluate its in vitro dissolution and in vivo pharmac
Publikováno v:
Archives of pharmacal research. 38(12)
In this study, the enteric-coated delayed-release pellets of duloxetine hydrochloride (DLX) were formulated using a fluidized bed coater. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto inert core pel
Autor:
Wansu Park, Ho-Taek Im, Young-Wook Choi, Sung-Hee Cho, Heon-Woo Lee, Jae-Hwan Rew, Kyung-Tae Lee
Publikováno v:
Rapid Communications in Mass Spectrometry. 20:1293-1298
A rapid and sensitive method for the quantitation of buspirone in human plasma by liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) was developed. Plasma samples were treated by liquid-liquid extraction with methyl
Autor:
Wansu Park, Jae-Hwan Rew, Young-Wook Choi, Kyung-Tae Lee, Sung-Hee Cho, Heon-Woo Lee, Ho-Taek Im, Chul-Soon Yong
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 35:461-465
A simple HPLC method with ultraviolet detection of nicardipine in human plasma was developed and validated. After drug extraction with solid phase extraction (SPE) method, chromatographic separation of nicardipine in plasma was achieved at with a col
Autor:
Jong-Hoen Won, Kyung-Tae Lee, Sung-Hee Cho, Wansu Park, Heon-Woo Lee, Jae-Hwan Rew, Ho-Taek Im
Publikováno v:
Journal of Korean Pharmaceutical Sciences. 35:355-360
The purpose of the present study was to evaluate the bioequivalence of two cetirizine HCl tablets, Zyrtec tablet (UCB Pharm. Co., Ltd. Korea, reference product) and Zyrix tablet (Kukje Pharm. Co., Ltd., Korea, test product), according to the guidelin