Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ho K Lee"'
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174935 (2017)
Anoctamin 1 (ANO1), a calcium-activated chloride channel, is highly amplified in prostate cancer, the most common form of cancer and leading causes of cancer death in men, and downregulation of ANO1 expression or its functional activity is known to i
Externí odkaz:
https://doaj.org/article/8e92665d69b140a9bc067e05a827d73b
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155771 (2016)
Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. To date, only a fe
Externí odkaz:
https://doaj.org/article/65ccc41fa1db43e88b5ab5b7aca30b52
Autor:
Jinhong Park, Poonam Khloya, Yohan Seo, Satish Kumar, Ho K Lee, Dong-Kyu Jeon, Sungwoo Jo, Pawan K Sharma, Wan Namkung
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149131 (2016)
The most common mutation of CFTR, affecting approximately 90% of CF patients, is a deletion of phenylalanine at position 508 (F508del, ΔF508). Misfolding of ΔF508-CFTR impairs both its trafficking to the plasma membrane and its chloride channel act
Externí odkaz:
https://doaj.org/article/661682eab0804e768bda8b7cb878e81b
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133656 (2015)
The expression levels of anoctamin 1 (ANO1, TMEM16A), a calcium-activated chloride channel (CaCC), are significantly increased in several tumors, and inhibition of ANO1 is known to reduce cell proliferation and migration. Here, we performed cell-base
Externí odkaz:
https://doaj.org/article/55a100620b514587a5dd68c5a7416d5b
Autor:
Bo Yi Kim, Changmok Oh, Dongkyu Jeon, Ikhyun Jun, Ho K. Lee, Bo-Rahm Kim, Jinhong Park, Kyoung Yul Seo, Kyeong-A Kim, Dami Lim, Seolhee Lee, Jooyun Lee, Hongchul Yoon, Tae-im Kim, Wan Namkung
Publikováno v:
Journal of Medicinal Chemistry. 66:413-434
Autor:
Dongkyu Jeon, Ikhyun Jun, Ho K. Lee, Jinhong Park, Bo-Rahm Kim, Kunhi Ryu, Hongchul Yoon, Tae-im Kim, Wan Namkung
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 5206
Cystic fibrosis transmembrane conductance regulator (CFTR) is highly expressed on the ocular epithelium and plays a pivotal role in the fluid secretion driven by chloride transport. Dry eye disease is one of the most common diseases with limited ther
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3954, p 3954 (2021)
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3954, p 3954 (2021)
Dry eye disease is one of the most common diseases, with increasing prevalence in many countries, but treatment options are limited. Cystic fibrosis transmembrane conductance regulator (CFTR) is a major ion channel that facilitates fluid secretion in
Publikováno v:
PLOS ONE(11): 5
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155771 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0155771 (2016)
Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. To date, only a fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15da45fe8c2bdcae892f4874cdd8a879
http://open-repository.kisti.re.kr/cube/handle/open_repository/474780.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/474780.do
Publikováno v:
Acta Radiologica. 53:682-688
Background Idiopathic intracranial hypertension (IIH) is a clinical disorder of unknown etiology manifesting with increased intracranial pressure in the absence of hydrocephalus, an underlying mass lesion, and demonstrating normal cerebrospinal fluid
Autor:
Dong Kyu Jeon, Jinhong Park, Satish Kumar, Ho K. Lee, Wan Namkung, Sungwoo Jo, Poonam Khloya, Pawan K. Sharma, Yohan Seo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0149131 (2016)
PLoS ONE, Vol 11, Iss 2, p e0149131 (2016)
The most common mutation of CFTR, affecting approximately 90% of CF patients, is a deletion of phenylalanine at position 508 (F508del, ΔF508). Misfolding of ΔF508-CFTR impairs both its trafficking to the plasma membrane and its chloride channel act