Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ho Jeong, Hong"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Insulin-like growth factor 1 (IGF1) regulates growth and differentiation. Here, authors report the atomic structure of the ternary complex (IGF1/IGF-binding protein3/acid labile subunit) and its assembly/disassembly mechanism for IGF bioavailability.
Externí odkaz:
https://doaj.org/article/798ec222fcee4dcbb60c66cd122017f6
Autor:
Gyunghee Jo, Jeomil Bae, Ho Jeong Hong, Ah-reum Han, Do-Kyun Kim, Seon Pyo Hong, Jung A Kim, Sangkyu Lee, Gou Young Koh, Ho Min Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Angiopoietin (Angpt)-Tie receptor 2 (Tie2) regulates vascular stability and is thus a potential therapeutic target in vascular diseases. Here, the authors report a Tie2-agonistic antibody which targets a site distinct from the Angpt 1-binding site an
Externí odkaz:
https://doaj.org/article/fc69bcd280cf4fe0bfa69e52efbb0a96
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1882 (2022)
NAD(H)/NADP(H)-dependent aldehyde/alcohol oxidoreductase (AAOR) participates in a wide range of physiologically important cellular processes by reducing aldehydes or oxidizing alcohols. Among AAOR substrates, furan aldehyde is highly toxic to microor
Externí odkaz:
https://doaj.org/article/0d971adad2c940db80bc76c1fe3ed8fb
Publikováno v:
International journal of molecular sciences. 23(3)
NAD(H)/NADP(H)-dependent aldehyde/alcohol oxidoreductase (AAOR) participates in a wide range of physiologically important cellular processes by reducing aldehydes or oxidizing alcohols. Among AAOR substrates, furan aldehyde is highly toxic to microor
Autor:
Do-Kyun Kim, Gyunghee Jo, Gou Young Koh, Jung A. Kim, Seon Pyo Hong, Ho Min Kim, Ho Jeong Hong, Sangkyu Lee, Ah-reum Han, Jeomil Bae
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Angiopoietin (Angpt)-Tie receptor 2 (Tie2) plays key roles in vascular development and homeostasis as well as pathological vascular remodeling. Therefore, Tie2-agonistic antibody and engineered Angpt1 variants have been developed as potential therape
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Biochemical and biophysical research communications. 529(2)
Legionella pneumophila is a flagellated pathogenic bacterium that causes atypical pneumonia called Legionnaires’ disease. The flagellum plays a key role in the pathogenesis of L. pneumophila in the host. The protein FlgL forms a junction between th
Autor:
Wan Seok Song, Tae Hee Kim, Geun-Shik Lee, Pyeung-Hyeun Kim, Hyun-Jeong Ko, Ho Jeong Hong, Sung-il Yoon, Seung Goo Kang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Bacteria move toward attractants and away from repellants by rotating their flagellum. The bacterial flagellum assembles through the ordered organization of more than 30 different proteins. Among the diverse flagellar proteins, FlgL forms the junctio
Publikováno v:
Journal of molecular biology. 429(6)
FliD is a self-oligomerizing structural protein that caps the growing end of the bacterial flagellar filament. FliD also plays a key role in the flagellar system by continuously adding a new flagellin protein to the tip of the filament. To structural
Autor:
Pyeung-Hyeun Kim, Wan Seok Song, Hyun-Jeong Ko, Seung Goo Kang, Geun-Shik Lee, Sung-il Yoon, Ho Jeong Hong, So Yeon Cho
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:a185-a185
Bacterial motility is provided by the flagellum. FliD is located at the distal end of the flagellum and plays a key role in the insertion of each flagellin protein at the growing tip of the flagellar filament. Because FliD functions as an oligomer, t