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pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis.

Autor: Kremer D; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Gruchot J; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Weyers V; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Oldemeier L; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Göttle P; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Healy L; Montreal Neurological Institute & Hospital, McGill University, Montreal, QC H4A 3K9, Canada., Ho Jang J; Montreal Neurological Institute & Hospital, McGill University, Montreal, QC H4A 3K9, Canada., Kang T Xu Y; Montreal Neurological Institute & Hospital, McGill University, Montreal, QC H4A 3K9, Canada., Volsko C; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Dutta R; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Trapp BD; Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195., Perron H; GeNeuro, CH-1228 Geneva, Switzerland., Hartung HP; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany., Küry P; Department of Neurology, Medical Faculty, Heinrich Heine University, 40225 Düsseldorf, Germany; kuery@uni-duesseldorf.de.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jul 23; Vol. 116 (30), pp. 15216-15225. Date of Electronic Publication: 2019 Jun 18.