Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker's yeast

Autor: Awan, AR, Blount, BA, Bell, DJ, Shaw, WM, Ho, JCH, McKiernan, RM, Ellis, T

Fungi are a valuable source of enzymatic diversity and therapeutic natural products including antibiotics. Here we engineer the baker’s yeast Saccharomyces cerevisiae to produce and secrete the antibiotic penicillin, a beta-lactam nonribosomal pept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::bd25938342f82e02ad0fda35b435efaa
http://hdl.handle.net/10044/1/48888

Histiocyte-rich ROS1-rearranged inflammatory myofibroblastic tumour of the trachea: A rare neoplasm presenting with asthma-like symptoms.

Autor: Kwok CT; Department of Respiratory Medicine Kowloon Hospital Hong Kong SAR China., Tsang JCH; Department of Pathology Queen Elizabeth Hospital Hong Kong SAR China., Lam M; Department of Clinical Oncology Princess Margaret Hospital Hong Kong SAR China., Ho SSK; Department of Medicine and Geriatrics Princess Margaret Hospital Hong Kong SAR China., Yuen CS; Department of Cardiothoracic Surgery Queen Mary Hospital Hong Kong SAR China., Yeung YC; Department of Medicine and Geriatrics Princess Margaret Hospital Hong Kong SAR China.

Publikováno v: Respirology case reports [Respirol Case Rep] 2024 Dec 03; Vol. 12 (12), pp. e70078. Date of Electronic Publication: 2024 Dec 03 (Print Publication: 2024).

Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents.

Autor: Rosa Duque JS; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Cheng SMS; School of Public Health, The University of Hong Kong, Hong Kong, China., Cohen CA; School of Public Health, The University of Hong Kong, Hong Kong, China.; HKU-Pasteur Research Pole, School of Public Health, The University of Hong Kong, Hong Kong, China., Leung D; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Wang X; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Mu X; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Chung Y; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Lau TM; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Wang M; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Zhang W; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Zhang Y; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Wong HHW; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Tsang LCH; School of Public Health, The University of Hong Kong, Hong Kong, China., Chaothai S; School of Public Health, The University of Hong Kong, Hong Kong, China., Kwan TC; School of Public Health, The University of Hong Kong, Hong Kong, China., Li JKC; School of Public Health, The University of Hong Kong, Hong Kong, China., Chan KCK; School of Public Health, The University of Hong Kong, Hong Kong, China., Luk LLH; School of Public Health, The University of Hong Kong, Hong Kong, China., Ho JCH; School of Public Health, The University of Hong Kong, Hong Kong, China., Li WY; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Lee AMT; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Lam JHY; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Chan SM; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Wong WHS; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Tam IYS; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China., Mori M; Research Institute for Bioresources and Biotechnology, Ishikawa Prefectural University, Nonoichi, Japan., Valkenburg SA; School of Public Health, The University of Hong Kong, Hong Kong, China. sophiev@hku.hk.; HKU-Pasteur Research Pole, School of Public Health, The University of Hong Kong, Hong Kong, China. sophiev@hku.hk.; Department of Microbiology and Immunology, Peter Doherty Institute for Infection, and Immunity, University of Melbourne, Melbourne, VIC, Australia. sophiev@hku.hk., Peiris M; School of Public Health, The University of Hong Kong, Hong Kong, China. malik@hku.hk.; Center for Immunology and Infection C2i, Hong Kong, China. malik@hku.hk., Tu W; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China. wwtu@hku.hk., Lau YL; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China. lauylung@hku.hk.

Publikováno v: World journal of pediatrics : WJP [World J Pediatr] 2024 Apr; Vol. 20 (4), pp. 353-370. Date of Electronic Publication: 2023 Dec 12.

Integrated Omics Approaches Revealed the Osmotic Stress-Responsive Genes and Microbiota in Gill of Marine Medaka.

Autor: Lai KP; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China.; Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Beibu Gulf University, Qinzhou, China.; Department of Chemistry, City University of Hong Konggrid.35030.35, Hong Kong SAR, China.; State Key Laboratory of Marine Pollution, City University of Hong Konggrid.35030.35, Hong Kong SAR, China., Zhu P; Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Beibu Gulf University, Qinzhou, China., Boncan DAT; School of Life Sciences, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Konggrid.10784.3a, Hong Kong SAR, China., Yang L; Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Beibu Gulf University, Qinzhou, China., Leung CCT; Department of Chemistry, City University of Hong Konggrid.35030.35, Hong Kong SAR, China., Ho JCH; Department of Chemistry, City University of Hong Konggrid.35030.35, Hong Kong SAR, China., Lin X; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Chan TF; School of Life Sciences, State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Konggrid.10784.3a, Hong Kong SAR, China., Kong RYC; Department of Chemistry, City University of Hong Konggrid.35030.35, Hong Kong SAR, China.; State Key Laboratory of Marine Pollution, City University of Hong Konggrid.35030.35, Hong Kong SAR, China.; Research Centre for the Oceans and Human Health, City University of Hong Kong Shenzhen Research Institute, Shenzhen, China., Tse WKF; Laboratory of Developmental Disorders and Toxicology, Center for Promotion of International Education and Research, Faculty of Agriculture, Kyushu University, Fukuoka, Japan.

Publikováno v: MSystems [mSystems] 2022 Apr 26; Vol. 7 (2), pp. e0004722. Date of Electronic Publication: 2022 Mar 14.

The use of glutathione to reduce oxidative stress status and its potential for modifying the extracellular matrix organization in cleft lip.

Autor: Li R; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China., Huang C; The Center for Data Science in Health and Medicine, Business School, Qingdao University, Qingdao, Shandong Province, China., Ho JCH; Department of Chemistry, City University of Hong Kong, Hong Kong SAR., Leung CCT; Department of Chemistry, City University of Hong Kong, Hong Kong SAR., Kong RYC; Department of Chemistry, City University of Hong Kong, Hong Kong SAR., Li Y; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China., Liang X; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China., Lai KP; Laboratory of Environmental Pollution and Integrative Omics, Guilin Medical University, Guilin, China; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China; Department of Chemistry, City University of Hong Kong, Hong Kong SAR. Electronic address: kengplai@cityu.edu.hk., Tse WKF; Center for Promotion of International Education and Research, Faculty of Agriculture, Kyushu University, Fukuoka, Japan. Electronic address: kftse@agr.kyushu-u.ac.jp.

Publikováno v: Free radical biology & medicine [Free Radic Biol Med] 2021 Feb 20; Vol. 164, pp. 130-138. Date of Electronic Publication: 2021 Jan 07.