Household environmental microbiota influences early-life eczema development.

Autor: Ta LDH; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tay CJX; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lay C; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Danone Nutricia Research, Singapore, Singapore., de Sessions PF; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan CPT; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tay MJY; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lau HX; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Zulkifli AB; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yap GC; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tham EH; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore., Ho EXP; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Goh AEN; Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Godfrey KM; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, SO16 6YD, UK.; Medical Research Council Life course Epidemiology Unit, Southampton, SO16 6YD, UK., Eriksson JG; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Finland., Knol J; Danone Nutricia Research, Utrecht, The Netherlands.; Wageningen University, Wageningen, The Netherlands., Gluckman PD; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Liggins Institute, University of Auckland, New Zealand., Chong YS; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Department of Obstetrics & Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Chan JKY; Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Tan KH; Department of Maternal Fetal Medicine, KK Women's and Children's Hospital, Singapore, Singapore., Chong KW; Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Goh SH; Allergy Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Cheng ZR; Respiratory Medicine Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore., Lee BW; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Shek LP; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, National University Health System, Singapore, Singapore., Loo EXL; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

Publikováno v: Environmental microbiology [Environ Microbiol] 2021 Dec; Vol. 23 (12), pp. 7710-7722. Date of Electronic Publication: 2021 Aug 12.

Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment.

Autor: Chng KR; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Li C; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Bertrand D; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Ng AHQ; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Kwah JS; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Low HM; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Tong C; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Natrajan M; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Zhang MH; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Xu L; Information Systems Technology and Design, Singapore University of Technology and Design, Singapore, Singapore., Ko KKK; Department of Microbiology, Singapore General Hospital, Singapore, Singapore.; Department of Molecular Pathology, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Graduate Medical School, Singapore, Singapore., Ho EXP; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Av-Shalom TV; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Teo JWP; Department of Laboratory Medicine, National University Hospital, Singapore, Singapore., Khor CC; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Chen SL; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA., Ng OT; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Marimuthu K; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ang B; National Centre for Infectious Diseases, Singapore, Singapore.; Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore., Nagarajan N; Computational and Systems Biology, Genome Institute of Singapore, Singapore, Singapore. nagarajann@gis.a-star.edu.sg.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. nagarajann@gis.a-star.edu.sg.

Publikováno v: Nature medicine [Nat Med] 2020 Jun; Vol. 26 (6), pp. 941-951. Date of Electronic Publication: 2020 Jun 08.

A double-blind randomized placebo-controlled trial of probiotics in systemic sclerosis associated gastrointestinal disease.

Autor: Low AHL; Department of Rheumatology and Immunology, Singapore General Hospital, The Academia, Level 4, 20 College Road 169856, Singapore; Duke-National University of Singapore Medical School, 8 College Road 169857, Singapore. Electronic address: andrea.low.h.l@singhealth.com.sg., Teng GG; Division of Rheumatology, National University Hospital, National University Health System, 5 Lower Kent Ridge Road 119074, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road 119228, Singapore., Pettersson S; Lee Kong Chian School of Medicine, Nanyang Technological University, 59 Nanyang Drive, Experimental Medicine Building 636921, Singapore; Singapore Centre for Environmental Life Sciences Engineering Microbiome Centre, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore., de Sessions PF; Genome Institute of Singapore, Agency for Science, Technology and Research, 60 Biopolis Street 138672, Singapore., Ho EXP; Genome Institute of Singapore, Agency for Science, Technology and Research, 60 Biopolis Street 138672, Singapore., Fan Q; Centre for Quantitative Medicine, Duke-NUS Medical School, 8 College Road 169857, Singapore., Chu CW; Genome Institute of Singapore, Agency for Science, Technology and Research, 60 Biopolis Street 138672, Singapore., Law AHN; Department of Rheumatology and Immunology, Singapore General Hospital, The Academia, Level 4, 20 College Road 169856, Singapore., Santosa A; Division of Rheumatology, National University Hospital, National University Health System, 5 Lower Kent Ridge Road 119074, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road 119228, Singapore., Lim AYN; Division of Rheumatology, National University Hospital, National University Health System, 5 Lower Kent Ridge Road 119074, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road 119228, Singapore., Wang YT; Gastroenterology and Hepatology, Singapore General Hospital, 20 College Road Singapore 169856., Haaland B; Centre for Quantitative Medicine, Duke-NUS Medical School, 8 College Road 169857, Singapore., Thumboo J; Department of Rheumatology and Immunology, Singapore General Hospital, The Academia, Level 4, 20 College Road 169856, Singapore; Duke-National University of Singapore Medical School, 8 College Road 169857, Singapore.

Publikováno v: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2019 Dec; Vol. 49 (3), pp. 411-419. Date of Electronic Publication: 2019 May 23.

Microbiome in the hair follicle of androgenetic alopecia patients.

Autor: Ho BS; Experimental Dermatology Group, Institute of Medical Biology, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., Ho EXP; GERMS Platform for microbial genomics, Genome Institute of Singapore, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., Chu CW; GERMS Platform for microbial genomics, Genome Institute of Singapore, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., Ramasamy S; Experimental Dermatology Group, Institute of Medical Biology, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., Bigliardi-Qi M; Experimental Dermatology Group, Institute of Medical Biology, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., de Sessions PF; GERMS Platform for microbial genomics, Genome Institute of Singapore, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore., Bigliardi PL; Experimental Dermatology Group, Institute of Medical Biology, A*STAR (Agency for Science, Technology and Research), Singapore, Singapore.; YLL School of Medicine, National University of Singapore and National University Hospital System NUHS, Singapore, Singapore.

Publikováno v: PloS one [PLoS One] 2019 May 03; Vol. 14 (5), pp. e0216330. Date of Electronic Publication: 2019 May 03 (Print Publication: 2019).

Human pharyngeal microbiota in age-related macular degeneration.

Autor: Ho EXP; Genome Institute of Singapore,Singapore, Singapore., Cheung CMG; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Sim S; Genome Institute of Singapore,Singapore, Singapore., Chu CW; Genome Institute of Singapore,Singapore, Singapore., Wilm A; Genome Institute of Singapore,Singapore, Singapore., Lin CB; Genome Institute of Singapore,Singapore, Singapore., Mathur R; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Wong D; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Chan CM; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Bhagarva M; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore, Singapore., Laude A; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore., Lim TH; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Davila S; Genome Institute of Singapore,Singapore, Singapore., Hibberd M; Genome Institute of Singapore,Singapore, Singapore.; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.

Publikováno v: PloS one [PLoS One] 2018 Aug 08; Vol. 13 (8), pp. e0201768. Date of Electronic Publication: 2018 Aug 08 (Print Publication: 2018).