Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

Autor: Hoang Thanh Hai, Le Thanh Hoang Nhat, Trinh Thi Bich Tram, Do Dinh Vinh, Artika P Nath, Joseph Donovan, Nguyen Thi Anh Thu, Dang Van Thanh, Nguyen Duc Bang, Dang Thi Minh Ha, Nguyen Hoan Phu, Ho Dang Trung Nghia, Le Hong Van, Michael Inouye, Guy E Thwaites, Nguyen Thuy Thuong Thuong

Publikováno v: eLife, Vol 13 (2024)

Mortality and morbidity from tuberculous meningitis (TBM) are common, primarily due to inflammatory response to Mycobacterium tuberculosis infection, yet the underlying mechanisms remain poorly understood. We aimed to uncover genes and pathways assoc

Externí odkaz: https://doaj.org/article/bc95681a731846ba918190c3d7e3cad9

Urinary catecholamine excretion, cardiovascular variability, and outcomes in tetanus

Autor: Duc Hong Du, Nguyen Quan Nhu Hao, Nguyen Van Hao, Tran Tan Thanh, Huynh Thi Loan, Lam Minh Yen, Tran Thi Diem Thuy, Duong Bich Thuy, Nguyen Thanh Nguyen, Nguyen Thi Phuong Dung, Evelyne Kestelyn, Ha Thi Hai Duong, Nguyen Thanh Phong, Pham Thi Tuyen, Nguyen Hoan Phu, Ho Dang Trung Nghia, Bui Thi Bich Hanh, Pham Kieu Nguyet Oanh, Phan Vinh Tho, Phung Tran Huy Nhat, Phan Nguyen Quoc Khanh, Duncan Wyncoll, Nicholas P. J. Day, Nguyen Van Vinh Chau, H. Rogier van Doorn, Le Van Tan, Ronald B. Geskus, C. Louise Thwaites

Publikováno v: Tropical Medicine and Health, Vol 51, Iss 1, Pp 1-6 (2023)

Abstract Severe tetanus is characterized by muscle spasm and cardiovascular system disturbance. The pathophysiology of muscle spasm is relatively well understood and involves inhibition of central inhibitory synapses by tetanus toxin. That of cardiov

Externí odkaz: https://doaj.org/article/cf80d55694944988ade9b4949dad3efc

Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam

Autor: Trinh Manh Hung, Nguyen Van Hao, Lam Minh Yen, Angela McBride, Vu Quoc Dat, H. Rogier van Doorn, Huynh Thi Loan, Nguyen Thanh Phong, Martin J. Llewelyn, Behzad Nadjm, Sophie Yacoub, C. Louise Thwaites, Sayem Ahmed, Nguyen Van Vinh Chau, Hugo C. Turner, The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators, Dang Phuong Thao, Dang Trung Kien, Doan Bui Xuan Thy, Dong Huu Khanh Trinh, Du Hong Duc, Ronald Geskus, Ho Bich Hai, Ho Quang Chanh, Ho Van Hien, Huynh Trung Trieu, Evelyne Kestelyn, Le Dinh Van Khoa, Le Thanh Phuong, Luu Hoai Bao Tran, Luu Phuoc An, Angela Mcbride, Nguyen Lam Vuong, Nguyen Quang Huy, Nguyen Than Ha Quyen, Nguyen Thanh Ngoc, Nguyen Thi Giang, Nguyen Thi Le Thanh, Nguyen Thi Phuong Dung, Nguyen Thi Phuong Thao, Ninh Thi Thanh Van, Phan Nguyen Quoc Khanh, Phung Khanh Lam, Phung Tran Huy Nhat, Guy Thwaites, Tran Minh Duc, Jennifer Ilo Van Nuil, Vu Ngo Thanh Huyen, Cao Thi Tam, Duong Bich Thuy, Ha Thi Hai Duong, Ho Dang Trung Nghia, Le Buu Chau, Le Mau Toan, Le Ngoc Minh Thu, Le Thi Mai Thao, Luong Thi Hue Tai, Nguyen Hoan Phu, Nguyen Quoc Viet, Nguyen Thanh Nguyen, Nguyen Thi Kim Anh, Nguyen Van Thanh Duoc, Pham Kieu Nguyet Oanh, Phan Thi Hong Van, Phan Tu Qui, Phan Vinh Tho, Truong Thi Phuong Thao, Natasha Ali, David Clifton, Mike English, Shadi Ghiasi, Heloise Greeff, Jannis Hagenah, Ping Lu, Jacob McKnight, Chris Paton, Pantelis Georgiou, Bernard Hernandez Perez, Kerri Hill-Cawthorne, Alison Holmes, Stefan Karolcik, Damien Ming, Nicolas Moser, Liane Canas, Alberto Gomez, Hamideh Kerdegari, Marc Modat, Reza Razavi, Linda Denehy, Luigi Pisani, Marcus Schultz

Publikováno v: Frontiers in Public Health, Vol 10 (2022)

BackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-inc

Externí odkaz: https://doaj.org/article/f7077071376a4b659d7c43626ab987a1

Enterovirus serotypes in patients with central nervous system and respiratory infections in Viet Nam 1997–2010

Autor: Nguyen Thi Thuy Chinh B’Krong, Ngo Ngoc Quang Minh, Phan Tu Qui, Tran Thi Hong Chau, Ho Dang Trung Nghia, Lien Anh Ha Do, Nguyen Ngoc Nhung, Nguyen Van Vinh Chau, Guy Thwaites, Le Van Tan, H. Rogier van Doorn, Tran Tan Thanh

Publikováno v: Virology Journal, Vol 15, Iss 1, Pp 1-8 (2018)

Abstract Background Enteroviruses are the most common causative agents of human illness. Enteroviruses have been associated with regional and global epidemics, recently, including with severe disease (Enterovirus A71 and D68), and are of interest as

Externí odkaz: https://doaj.org/article/0d07d42d1a224e7dab41ab5998b9b6c2

Aetiology and Potential Animal Exposure in Central Nervous System Infections in Vietnam

Autor: Brindle, Hannah E, Nadjm, Behzad, Choisy, Marc, Christley, Rob, Griffiths, Michael, Baker, Stephen, Bryant, Juliet E, Campbell, James I, Nguyen, Van Vinh Chau, Nguyen, Thi Ngoc Diep, Vu, Ty Thi Hang, Nguyen, Van Hung, Hoang, Bao Long, Le, Xuan Luat, Pham, Ha My, Ta, Thi Dieu Ngan, Ho, Dang Trung Nghia, Tran, Thua Nguyen, Nguyen, Thi Han Ny, Tran, My Phuc, Pham, Thi Hong Phuong, Le, Van Tan, Nguyen, Dac Thuan, Hau, Thi Thu Trang, Nguyen, Ngoc Vinh, Wertheim, Heiman FL, Thwaites, Guy E, Van Doorn, H Rogier, VIZIONS Consortium

An estimated 73% of emerging infections are zoonotic in origin, with animal contact and encroachment on their habitats increasing the risk of spill-over events. In Vietnam, close exposure to a wide range of animals and animal products can lead to acq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8b1d2609a04ac18df8b99fe655ac44