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Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies

Autor: Traylor, M, Farrall, M, Holliday, EG, Sudlow, C, Hopewell, JC, Cheng, YC, Fornage, M, Ikram, MA, Malik, R, Bevan, S, Thorsteinsdottir, U, Nalls, MA, Longstreth, WT, Wiggins, KL, Yadav, S, Parati, EA, DeStefano, AL, Worrall, BB, Kittner, SJ, Khan, MS, Reiner, AP, Helgadottir, A, Achterberg, S, Fernandez-Cadenas, I, Abboud, S, Schmidt, R, Walters, M, Chen, WM, Ringelstein, EB, O'Donnell, M, Ho, WK, Pera, J, Lemmens, R, Norrving, B, Higgins, P, Benn, M, Sale, M, Kuhlenbäumer, G, Doney, ASF, Vicente, AM, Delavaran, H, Algra, A, Davies, G, Oliveira, SA, Palmer, CNA, Deary, I, Schmidt, H, Pandolfo, M, Montaner, J, Carty, C, de Bakker, PIW, Kostulas, K, Ferro, JM, van Zuydam, NR, Valdimarsson, E, Nordestgaard, BG, Lindgren, A, Thijs, V, Slowik, A, Saleheen, D, Paré, G, Berger, K, Thorleifsson, G, Hofman, A, Mosley, TH, Mitchell, BD, Furie, K, Clarke, R, Levi, C, Seshadri, S, Gschwendtner, A, Boncoraglio, GB, Sharma, P, Bis, JC, Gretarsdottir, S, Psaty, BM, Rothwell, PM, Rosand, J

Publikováno v: The Lancet Neurology
The Lancet Neurology, 11(11), 951-962
Traylor, M, Farrall, M, Holliday, E G, Sudlow, C, Hopewell, J C, Cheng, Y-C, Fornage, M, Ikram, M A, Malik, R, Bevan, S, Thorsteinsdottir, U, Nalls, M A, Longstreth, W, Wiggins, K L, Yadav, S, Parati, E A, Destefano, A L, Worrall, B B, Kittner, S J, Khan, M S, Reiner, A P, Helgadottir, A, Achterberg, S, Fernandez-Cadenas, I, Abboud, S, Schmidt, R, Walters, M, Chen, W-M, Ringelstein, E B, O'Donnell, M, Ho, W K, Pera, J, Lemmens, R, Norrving, B, Higgins, P, Benn, M, Sale, M, Kuhlenbäumer, G, Doney, A S F, Vicente, A M, Delavaran, H, Algra, A, Davies, G, Oliveira, S A, Palmer, C N A, Deary, I, Schmidt, H, Pandolfo, M & Montaner, J & Carty, C 2012, ' Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration) : a meta-analysis of genome-wide association studies ', Lancet Neurology, vol. 11, no. 11, pp. 951-62 . https://doi.org/10.1016/S1474-4422(12)70234-X
Lancet Neurology, 11(11), 951-962. Lancet Publishing Group
The Lancet. Neurology
The Lancet Neurology; Vol 11

Background: Various genome-wide association studies (GWAS) have been done in ischaemic stroke, identifying a few loci associated with the disease, but sample sizes have been 3500 cases or less. We established the METASTROKE collaboration with the aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379db6159900ded79d8c403cab3986e0
https://openaccess.sgul.ac.uk/id/eprint/101492/1/mmc1.pdf

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