Zobrazeno 1 - 10
of 376
pro vyhledávání: '"HnRNPK"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 12, Pp 1638-1643 (2024)
Objective To explore the role of ATM/hnRNPK signaling in the adriamycin resistance of acute myeloid leukemia. Methods Expression of ATM was examined in the adriamycin resistant and sensitive leukemia cell strains with Western blot. ATM expression was
Externí odkaz:
https://doaj.org/article/c295176d550146b5966c143b8a0df35e
Publikováno v:
Zhongguo aizheng zazhi, Vol 34, Iss 10, Pp 931-943 (2024)
Background and purpose: Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA special binding protein that participates in regulating the expression of related genes and protein translation. It has been linked to the malignant occurrence and d
Externí odkaz:
https://doaj.org/article/863ffcce94bc4fd3b21a6bcc39a6e029
Publikováno v:
Cell Insight, Vol 3, Iss 6, Pp 100198- (2024)
The methyltransferase SETD3 is an enzyme essential for catalyzing histidine-73 methylation on β-Actin, thereby promoting its polymerization and regulating muscle contraction. Although increasing evidence suggests that SETD3 is involved in multiple p
Externí odkaz:
https://doaj.org/article/d3ccfd0169af4e2e8a3b3900c6183d37
Autor:
Wanzhen Zhuang, Chengxiu Liu, Yilin Hong, Yue Zheng, Minjian Huang, Haijun Tang, Lilan Zhao, Zhixin Huang, Mingshu Tu, Lili Yu, Jianlin Chen, Yi Zhang, Xiongfeng Chen, Fan Lin, Qi Gao, Chundong Yu, Yi Huang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Aberrant fucosylation observed in cancer cells contributes to an augmented release of fucosylated exosomes into the bloodstream, where miRNAs including miR-4732-3p hold promise as potential tumor biomarkers in our pilot study. How
Externí odkaz:
https://doaj.org/article/f12f82cfad2e48f18714e08c1128f6c9
Autor:
Zihan Xi, Haohao Huang, Jin Hu, Yuanhang Yu, Xianxiong Ma, Ming Xu, Jie Ming, Lei Li, Hui Zhang, Hengyu Chen, Tao Huang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Triple-negative breast cancer is a complex breast malignancy subtype characterized by poor prognosis. The pursuit of effective therapeutic approaches for this subtype is considerably challenging. Notably, recent research has illum
Externí odkaz:
https://doaj.org/article/7dc0d5241320452ebd62229b8f1ff5c5
Autor:
Te Zhang, Yahui Leng, Mengjing Duan, Zihang Li, Yongqing Ma, Chengyang Huang, Qin Shi, Yi Wang, Chengcheng Wang, Dandan Liu, Xuan Zhao, Shuang Cheng, Ao Liu, Yang Zhou, Jiaqi Liu, Zhongqiu Pan, Huimei Zhang, Li Shen, Hongyan Zhao
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background The incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first. Methods The expression of GAS5 is low in ovarian cancer and is associated with the low survival of ovarian cancer pati
Externí odkaz:
https://doaj.org/article/af6e999150c540de9d3e7097d580dc54
Autor:
Arwa Fallatah, Dimitrios G. Anastasakis, Amirhossein Manzourolajdad, Pooja Sharma, Xiantao Wang, Alexis Jacob, Sarah Alsharif, Ahmed Elgerbi, Pierre A. Coulombe, Markus Hafner, Byung Min Chung
Publikováno v:
BMC Molecular and Cell Biology, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA processing and long non-coding RNA localization in the nucleus. It was previously shown that shuttling of HNRNPK to the cytoplasm promotes cell proliferation an
Externí odkaz:
https://doaj.org/article/1d2aae9ceeed43c083f5ac31343b76dc
Autor:
Shuang Wu, Xiangyu Dai, Zhipu Zhu, Dianhui Fan, Su Jiang, Yi Dong, Bing Chen, Qi Xie, Zhihui Yao, Qun Li, Rick Francis Thorne, Yao Lu, Hao Gu, Wanglai Hu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 49, Iss , Pp 100971- (2024)
More than half of all cancers demonstrate aberrant c-Myc expression, making this arguably the most important human oncogene. Deregulated long non-coding RNAs (lncRNAs) are also commonly implicated in tumorigenesis, and some limited examples have been
Externí odkaz:
https://doaj.org/article/e594d899c9254c1e8b740f3363cfd418
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Protein‒protein interactions (PPIs) are the foundation of the life activities of cells. TurboID is a biotin ligase with higher catalytic efficiency than BioID or APEX that reduces the required labeling time from 18 h to 10 min.
Externí odkaz:
https://doaj.org/article/9b68ff5b7f5a420bb8c685f58b6d0924
Autor:
Leandro Fernández-García, Constanza Ahumada-Marchant, Pablo Lobos-Ávila, Bastián Brauer, Fernando J. Bustos, Gloria Arriagada
Publikováno v:
Viruses, Vol 16, Iss 3, p 403 (2024)
LTR-retrotransposons are transposable elements characterized by the presence of long terminal repeats (LTRs) directly flanking an internal coding region. They share genome organization and replication strategies with retroviruses. Steamer-like Elemen
Externí odkaz:
https://doaj.org/article/e26fd02dfa4442059dd4db034eb65857