Zobrazeno 1 - 10
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pro vyhledávání: '"HmuY"'
Autor:
Michał Śmiga, Teresa Olczak
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionPorphyromonas gingivalis and Porphyromonas endodontalis belong to the Bacteroidota phylum. Both species inhabit the oral cavity and can be associated with periodontal diseases. To survive, they must uptake heme from the host as an iron an
Externí odkaz:
https://doaj.org/article/a9ba7f6d81fb4b74bf98d7d491b5a94a
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTPorphyromonas gingivalis strains exhibit different phenotypes in vitro, different virulence potential in animal models, and different associations with human diseases, with strains classified as virulent/more virulent (e.g., A7436 and W83) or
Externí odkaz:
https://doaj.org/article/473cfd776aa84558899d3fa9e251c3a1
Autor:
Yueying Zhu, Delphine Lechardeur, Jean-François Bernardet, Brigitte Kerouault, Cyprien Guérin, Dimitri Rigaudeau, Pierre Nicolas, Eric Duchaud, Tatiana Rochat
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1221-1241 (2022)
Bacterial pathogens have a critical impact on aquaculture, a sector that accounts for half of the human fish consumption. Flavobacterium psychrophilum (phylum Bacteroidetes) is responsible for bacterial cold-water disease in salmonids worldwide. The
Externí odkaz:
https://doaj.org/article/795ed96466d9448187e7cc3e4abd46c6
Akademický článek
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Publikováno v:
Molecules, Vol 27, Iss 5, p 1703 (2022)
To acquire heme, Porphyromonas gingivalis uses a hemophore-like protein (HmuY). HmuY sequesters heme from host hemoproteins or heme-binding proteins produced by cohabiting bacteria, and delivers it to the TonB-dependent outer-membrane receptor (HmuR)
Externí odkaz:
https://doaj.org/article/f1c8a172d9764e5ba2a31999996f8095
Akademický článek
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Autor:
Michał Śmiga, John W. Smalley, Paulina Ślęzak, Jason L. Brown, Klaudia Siemińska, Rosalind E. Jenkins, Edwin A. Yates, Teresa Olczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 12084 (2021)
The non-enzymatic addition of glucose (glycation) to circulatory and tissue proteins is a ubiquitous pathophysiological consequence of hyperglycemia in diabetes. Given the high incidence of periodontitis and diabetes and the emerging link between the
Externí odkaz:
https://doaj.org/article/d0c6fa6669a445a9babe3ca49a032b35
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Porphyromonas gingivalis, a keystone pathogen of chronic periodontitis, uses ferric uptake regulator homolog (PgFur) to regulate production of virulence factors. This study aimed to characterize PgFur protein in regard to its structure-function relat
Externí odkaz:
https://doaj.org/article/b6c6edb995da4d0daaa10ac9acf00fff
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2237 (2021)
Human oral and gut microbiomes are crucial for maintenance of homeostasis in the human body. Porphyromonas gingivalis, the key etiologic agent of chronic periodontitis, can cause dysbiosis in the mouth and gut, which results in local and systemic inf
Externí odkaz:
https://doaj.org/article/c5a06bd9c42d43eb94b390e209c33d70
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4150 (2020)
The oral cavity of healthy individuals is inhabited by commensals, with species of Streptococcus being the most abundant and prevalent in sites not affected by periodontal diseases. The development of chronic periodontitis is linked with the environm
Externí odkaz:
https://doaj.org/article/596abda348c841bd83e058df6387cbb4