Zobrazeno 1 - 10
of 1 199
pro vyhledávání: '"Hmox1"'
Autor:
Jinfa Huang, Ruiwan Tan
Publikováno v:
BMC Women's Health, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background This study investigates the intricate role of Heme Oxygenase 1 (HMOX1) in ovarian cancer, emphasizing its prognostic significance, influence on immune cell infiltration, and impact on the malignant characteristics of primary ovari
Externí odkaz:
https://doaj.org/article/1666e1db7314450da61547ca94049523
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 2, Pp 307-317 (2024)
Acute lymphoblastic leukemia (ALL) is the most prevailing cancer among children. Despite extensive studies, ALL etiology is still an unsolved puzzle. Long non-coding RNAs (lncRNAs) emerged as key mediators in cancer etiology. Several lncRNAs are dysr
Externí odkaz:
https://doaj.org/article/5ddc162f11ac4cdfa15a2ab5fbf5e2a3
Autor:
Meng Chen, Shengli Ma, Wenbo Ji, Weihua Hu, Jiguang Gao, Jianke Yang, Yu Liu, Qianwen Cui, Shasha Yang, Xiaohui Xu, Haiming Dai, Lei Hu
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e38021- (2024)
Background: Because adverse reactions or drug resistance are often found after current chemotherapies for metastatic colorectal cancer (mCRC), new treatments are still in demand. Shenqi Sanjie Granules (SSG), an antitumor compound preparation of trad
Externí odkaz:
https://doaj.org/article/8e5b7e0ce4b04d5ab78d0c70194e4438
Publikováno v:
Cancer Pathogenesis and Therapy, Vol 2, Iss 2, Pp 65-73 (2024)
The significance of the heme-metabolizing enzyme heme oxygenase-1 (HMOX1) in the pathogenesis of colorectal cancer (CRC) has not been fully explored. HMOX1 cytoprotection is imperative to limit oxidative stress. However, its roles in preventing carci
Externí odkaz:
https://doaj.org/article/877f774adf28498fa9c16b1f1e46cf8a
Autor:
Yu Zhang, Youluan Jiang, Xiaoqian Dong, Shuwen Luo, Guoyu Jiao, Kaiqi Weng, Qiang Bao, Yang Zhang, Wanwipa Vongsangnak, Guohong Chen, Qi Xu
Publikováno v:
Poultry Science, Vol 103, Iss 8, Pp 103912- (2024)
ABSTRACT: The proliferation and death of granulosa cells (GCs) in poultry play a decisive role in follicular fate and egg production. The follicular fluid (FF) contains a variety of nutrients and genetic substances to ensure the communication between
Externí odkaz:
https://doaj.org/article/3deb5e38f8a947fca981f4cc2aa4e614
Autor:
Joanna Czarnecka-Herok, Kexin Zhu, Jean-Michel Flaman, Delphine Goehrig, Mathieu Vernier, Gabriela Makulyte, Aline Lamboux, Helena Dragic, Muriel Rhinn, Jean-Jacques Médard, Gilles Faury, Philippe Bertolino, Vincent Balter, Romain Debret, Serge Adnot, Nadine Martin, David Bernard
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103204- (2024)
The ELN gene encodes tropoelastin which is used to generate elastic fibers that insure proper tissue elasticity. Decreased amounts of elastic fibers and/or accumulation of bioactive products of their cleavage, named elastokines, are thought to contri
Externí odkaz:
https://doaj.org/article/7802765a7933406fa2443144126cebb7
Autor:
Sai Santhosha Mrudula Alla, Pahel Agarwal, Dhruv J. Shah, Waseem Abrar Shajahan, Rakshna Ramsundar, Deekshitha Alla, Madhavi Ravulapalli, Satya Bora, Sanjay Pillai, Ruth G. Bayeh, Uday Kumar Repalle, Fnu Suhani
Publikováno v:
Clinical Case Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Key Clinical Message Heme oxygenase deficiency, a rare condition disrupting heme metabolism, has only nine reported cases. We present a 3‐year‐old boy with dysmorphic facies, asplenia, and normal bilirubin levels despite ongoing hemolysis. Blood
Externí odkaz:
https://doaj.org/article/b4155e7938434df9b81ab8ddc9b4b691
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background The key complication of myocardial infarction therapy is myocardial ischemia/reperfusion injury (MI/RI), and there is no effective treatment. The present study elucidates the mechanism of action of lncRNA KCNQ1OT1 in alleviating M
Externí odkaz:
https://doaj.org/article/a81d065c4fc0414db8c120db8828bdf2
Autor:
Shanhui Liu, Yan Tao, Shan Wu, Jiawei Lin, Shengjun Fu, Jianzhong Lu, Jing Zhang, Beitang Fu, Erdong Zhang, Jing Xu, Jiaxuan Wang, Lanlan Li, Lei Zhang, Zhiping Wang
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background Sanguinarine chloride (S.C) is a benzophenanthrine alkaloid derived from the root of sanguinaria canadensis and other poppy-fumaria species. Studies have reported that S.C exhibits antioxidant, anti-inflammatory, proapoptotic, and
Externí odkaz:
https://doaj.org/article/5686950e7e9046709c56a696a984f4d6
Autor:
Hareram Pandey, Kanwaljeet Singh, Ravi Ranjan, Jasmita Dass, Seema Tyagi, Tulika Seth, Renu Saxena, Manoranjan Mahapatra
Publikováno v:
Journal of Laboratory Physicians, Vol 15, Iss 04, Pp 583-589 (2023)
Introduction Fetal hemoglobin (HbF) levels play significant role in lowering down the morbidity and mortality in sickle cell disease (SCD) patients. Coinheritance of heme oxygenase-1 (HMOX1) rs2071746:A > T polymorphism may contribute to variable HbF
Externí odkaz:
https://doaj.org/article/4ed4ef64e0814337ac78c8886ba6f8d0