0521. A functional citrulline-arginine-no pathway and nos3 complex is essential to maintain microcirculatory function during endotoxemia

Autor: Peter Brouckaert, Benjamin Vandendriessche, Bap Bessems, Martijn Poeze, Anje Cauwels, Wap Buurman, K. A. P. Wijnands, Hmh van Eijk, Jacob J. Briedé, Dennis M. Meesters

Publikováno v: Intensive Care Medicine Experimental

Sepsis is associated with high mortality rates as a result of the development of multiple organ failure (MOF). In MOF the competition for the amino acid arginine between the microcirculation and the inflammatory response is important. The endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a8ae1093bfec5a04e7e3e36bb480e5
http://europepmc.org/articles/PMC4796301

Intestinal permeability before and after albendazole treatment in low and high socioeconomic status schoolchildren in Makassar, Indonesia.

Autor: Amaruddin AI; Department of Parasitology, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia.; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands., Koopman JPR; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands., Muhammad M; Department of Pharmacology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia., Lenaerts K; Department of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6229 HX, Maastricht, The Netherlands., van Eijk HMH; Department of Surgery, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, 6229 HX, Maastricht, The Netherlands., Brienen EAT; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands., Geelen AR; Experimental Bacteriology, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Center for Microbiome Analyses and Therapeutics, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., van Lieshout L; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands., Wahyuni S; Department of Parasitology, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia., Kuijper EJ; Experimental Bacteriology, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Center for Microbiome Analyses and Therapeutics, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Zwittink RD; Experimental Bacteriology, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.; Center for Microbiome Analyses and Therapeutics, Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Hamid F; Department of Microbiology, Faculty of Medicine, Hasanuddin University, Jalan Perintis Kemerdekaan Km. 10 Kampus Tamalanrea, Makassar, 90245, Indonesia. firdaus.hamid@gmail.com., Sartono E; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands., Yazdanbakhsh M; Department of Parasitology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands. m.yazdanbakhsh@lumc.nl.

Publikováno v: Scientific reports [Sci Rep] 2022 Mar 01; Vol. 12 (1), pp. 3394. Date of Electronic Publication: 2022 Mar 01.

Mass spectrometry imaging of L-[ring- ¹³ C 6 ]-labeled phenylalanine and tyrosine kinetics in non-small cell lung carcinoma.

Autor: Cao J; Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands., Balluff B; Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands., Arts M; Department of General Surgery (NUTRIM), Maastricht University, Maastricht, The Netherlands., Dubois LJ; The M-Lab, Department of Precision Medicine (GROW), Maastricht University, Maastricht, The Netherlands., van Loon LJC; Department of Human Biology (NUTRIM), Maastricht University, Maastricht, The Netherlands., Hackeng TM; Department of Biochemistry (CARIM), Maastricht University, Maastricht, The Netherlands., van Eijk HMH; Department of General Surgery (NUTRIM), Maastricht University, Maastricht, The Netherlands., Eijkel G; Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands., Heij LR; Department of General Surgery (NUTRIM), Maastricht University, Maastricht, The Netherlands.; Department of General, Gastrointestinal, Hepatobiliary and Transplant Surgery, RWTH Aachen University Hospital, Aachen, Germany.; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany., Soons Z; Department of General Surgery (NUTRIM), Maastricht University, Maastricht, The Netherlands.; Joint Research Center for Computational Biomedicine , RWTH Aachen University Hospital , Aachen, Germany., Olde Damink SWM; Department of General Surgery (NUTRIM), Maastricht University, Maastricht, The Netherlands.; Department of General, Gastrointestinal, Hepatobiliary and Transplant Surgery, RWTH Aachen University Hospital, Aachen, Germany., Heeren RMA; Maastricht MultiModal Molecular Imaging institute (M4I), Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands. r.heeren@maastrichtuniversity.nl.

Publikováno v: Cancer & metabolism [Cancer Metab] 2021 Jun 11; Vol. 9 (1), pp. 26. Date of Electronic Publication: 2021 Jun 11.

Glutamine synthetase in muscle is required for glutamine production during fasting and extrahepatic ammonia detoxification.

Autor: He Y; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Hakvoort TBM; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Köhler SE; Departments of Anatomy & Embryology and Surgery, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., Vermeulen JLM; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., de Waart DR; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., de Theije C; Departments of Anatomy & Embryology and Surgery, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., Ten Have GAM; University of Maastricht, 6200 MD Maastricht, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., van Eijk HMH; University of Maastricht, 6200 MD Maastricht, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., Kunne C; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Labruyere WT; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Houten SM; Laboratory of Genetic Metabolic Diseases, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., Sokolovic M; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Ruijter JM; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam., Deutz NEP; University of Maastricht, 6200 MD Maastricht, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands., Lamers WH; Academic Medical Center Liver Center and Department of Anatomy & Embryology, Academic Medical Center, University of Amsterdam, Meibergdreef 69-71, 1105 BK Amsterdam; Departments of Anatomy & Embryology and Surgery, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Electronic address: w.h.lamers@amc.uva.nl.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2010 Mar 26; Vol. 285 (13), pp. 9516-9524. Date of Electronic Publication: 2010 Jan 11.