Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hlaing Nwe Thynn"'
Autor:
Xiao-Feng Chen, Ming-Rui Guo, Yuan-Yuan Duan, Feng Jiang, Hao Wu, Shan-Shan Dong, Xiao-Rong Zhou, Hlaing Nwe Thynn, Cong-Cong Liu, Lin Zhang, Yan Guo, Tie-Lin Yang
Publikováno v:
JCI Insight, Vol 5, Iss 17 (2020)
More than 90% of autoimmune-associated variants are located in noncoding regions, leading to challenges in deciphering the underlying causal roles of functional variants and genes and biological mechanisms. Therefore, to reduce the gap between tradit
Externí odkaz:
https://doaj.org/article/cbfe984a4aa04967a319c7af4037733a
Autor:
Xiao-Feng Chen, Nai-Ning Wang, Shan-Shan Dong, Hao Chen, Fu-Ling Zhou, Ruo-Han Hao, Yi-Xiao Chen, Tie-Lin Yang, Ming-Rui Guo, Yan Guo, Yuan-Yuan Duan, Shi Yao, Jia-Bin Chen, Wei-Xin Hu, Yu Rong, Yu-Jie Zhang, Hlaing Nwe Thynn
Publikováno v:
Bioinformatics. 36:4739-4748
Motivation CircRNAs are an abundant class of non-coding RNAs with widespread, cell-/tissue-specific patterns. Previous work suggested that epigenetic features might be related to circRNA expression. However, the contribution of epigenetic changes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d3100ee9cee642ab3e1309469a663a
https://doi.org/10.1093/bioinformatics/btaa567
https://doi.org/10.1093/bioinformatics/btaa567
Publikováno v:
Journal of Immunological Sciences. 4:6-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8017b0a175f47f76ad22ed83299d1b3
https://doi.org/10.29245/2578-3009/2020/1.1182
https://doi.org/10.29245/2578-3009/2020/1.1182
Autor:
Yan Guo, Yu Rong, Dong-Li Zhu, Hlaing Nwe Thynn, Wei-Xin Hu, Shan-Shan Dong, Xiao-Feng Chen, Hao Chen, Bing-Jie Lu, Yi-Xiao Chen, Tie-Lin Yang, Nai-Ning Wang
Publikováno v:
Journal of Bone and Mineral Research. 33:1335-1346
RANKL is a key regulator involved in bone metabolism, and a drug target for osteoporosis. The clinical diagnosis and assessment of osteoporosis are mainly based on bone mineral density (BMD). Previous powerful genomewide association studies (GWASs) h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec1275554b80104831371d3a74266221
https://doi.org/10.1002/jbmr.3419
https://doi.org/10.1002/jbmr.3419
Autor:
Shan-Shan Dong, Jun-Ling Gao, Ruo-Han Hao, Meng Li, Yan Guo, Hlaing Nwe Thynn, Dong-Li Zhu, Wei Huang
Publikováno v:
Endocrine. 59:296-303
Animal-based studies have reported a decrease in bone mass resulting from high level of fibroblast growth factor 21 (FGF21). However, the correlation between plasma FGF21 levels and bone mineral density (BMD) is paradoxical in previous human-based st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc8ee40160efb89a357ad4bc76f4e72
https://doi.org/10.1007/s12020-017-1507-y
https://doi.org/10.1007/s12020-017-1507-y
Autor:
Xiao-Feng Chen, Yu-Jie Zhang, Yi-Xiao Chen, Tie-Lin Yang, Shi Yao, Liqiang Zhi, Hlaing Nwe Thynn, Jia-Bin Chen, Yan Guo, Shan-Shan Dong
Publikováno v:
Journal of Cancer
Although genome-wide association studies (GWASs) have identified some risk single-nucleotide polymorphisms in East Asian never-smoking females, the unexplained missing heritability is still required to be investigated. Runs of homozygosity (ROHs) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fe03abc8f2d66ee46232c3c1c326f9
https://doi.org/10.7150/jca.22855
https://doi.org/10.7150/jca.22855
Autor:
Tie-Lin Yang, Lin Zhang, Hao Wu, Shan-Shan Dong, Yan Guo, Hlaing Nwe Thynn, Yuan-Yuan Duan, Min-Rui Guo, Xiao-Feng Chen, Feng Jiang, Cong-Cong Liu
The genome-wide association studies (GWAS) have identified hundreds of susceptibility loci associated with autoimmune diseases. However, over 90% of risk variants are located in the noncoding regions, leading to great challenges in deciphering the un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac4c76aa97ce52f40f94d0906c67d0e
Autor:
Man Yang, Huan-Huan Chen, Xiao-Feng Chen, Yu Rong, Nai-Ning Wang, Wei-Xin Hu, Hao Chen, Hlaing Nwe Thynn, Tie-Lin Yang, Feng Jiang, Dong-Li Zhu, Bing-Jie Lu, Yuan-Yuan Duan, Shan-Shan Dong, Yan Guo
Both Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc) are autoimmune diseases sharing similar genetic backgrounds. Genome-wide association studies (GWASs) have constantly disclosed numerous genetic variants conferring to both disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd52be850737f72b76631fbd4fec83b
https://doi.org/10.1101/533661
https://doi.org/10.1101/533661
Autor:
Shan-Shan Dong, Cong-Cong Liu, Yuan-Yuan Duan, Tie-Lin Yang, Feng Jiang, Lin Zhang, Min-Rui Guo, Yan Guo, Hlaing Nwe Thynn, Xiao-Feng Chen
Publikováno v:
SSRN Electronic Journal.
Over 90% of autoimmune diseases risk variants are located in the noncoding region, leading to great challenge in deciphering the underlying causal functional variants/genes and biological mechanisms. Here we devised an integrative analysis strategy n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88a4205a6d2a4bae1749a3eb7bca2c9
https://doi.org/10.2139/ssrn.3322367
https://doi.org/10.2139/ssrn.3322367
Autor:
Feng Jiang, Hao Chen, Bing-Jie Lu, Man Yang, Yuan-Yuan Duan, Nai-Ning Wang, Xiao-Feng Chen, Yan Guo, Yu Rong, Shan-Shan Dong, Wei-Xin Hu, Huan-Huan Chen, Hlaing Nwe Thynn, Tie-Lin Yang, Dong-Li Zhu
Publikováno v:
Journal of Investigative Dermatology. 140:348-360.e11
Both systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) are autoimmune diseases sharing similar genetic backgrounds. Genome-wide association studies have constantly disclosed numerous genetic variants conferring to both disease risks at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266c4b3ecada72b76a537077dd84c5c9
https://doi.org/10.1016/j.jid.2019.06.147
https://doi.org/10.1016/j.jid.2019.06.147