CXCR4 and CCR5 on human thymocytes: biological function and role in HIV-1 infection

Autor: Mb, Zaitseva, Lee S, Ronald Rabin, Hl, Tiffany, Jm, Farber, Kw, Peden, Pm, Murphy, Golding H

Publikováno v: Europe PubMed Central

Thymocyte infection with HIV-1 is associated with thymic involution and impaired thymopoiesis, particularly in pediatric patients. To define mechanisms of thymocyte infection, we examined human thymocytes for expression and function of CXCR4 and CCR5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dcf57dc9d1a1783470187a2a8e3d8961
https://pubmed.ncbi.nlm.nih.gov/9743377

A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family

Autor: Pm, Murphy, Ozçelik T, Rt, Kenney, Hl, Tiffany, David McDermott, Francke U

Publikováno v: Europe PubMed Central

Phagocytic cells of many higher species express calcium mobilizing G protein-coupled receptors for bacterial N-formyl peptides which mediate chemotaxis, degranulation, and the respiratory burst. cDNA encoding an N-formyl peptide receptor (FPR) has be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e0f34b9dc9eb9df3203bb8d34a06076
http://europepmc.org/abstract/med/1373134

Characterization of Fpr-rs8, an atypical member of the mouse formyl peptide receptor gene family.

Autor: Tiffany HL; Molecular Signaling Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Gao JL, Roffe E, Sechler JM, Murphy PM

Publikováno v: Journal of innate immunity [J Innate Immun] 2011; Vol. 3 (5), pp. 519-29. Date of Electronic Publication: 2011 Jun 17.

CXCL12 signaling is independent of Jak2 and Jak3.

Autor: Moriguchi M; Molecular Immunology and Inflammation Branch, NIAMS, Laboratory of Host Defenses, NIAID, and Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA., Hissong BD, Gadina M, Yamaoka K, Tiffany HL, Murphy PM, Candotti F, O'Shea JJ

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2005 Apr 29; Vol. 280 (17), pp. 17408-14. Date of Electronic Publication: 2004 Dec 20.

Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain.

Autor: Tiffany HL; Molecular Signaling and Genetic Immunotherapy Sections, Laboratory of Host Defenses, NIAID, National Institutes of Health, Bethesda, Maryland 20982, USA., Lavigne MC, Cui YH, Wang JM, Leto TL, Gao JL, Murphy PM

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2001 Jun 29; Vol. 276 (26), pp. 23645-52. Date of Electronic Publication: 2001 Apr 20.