Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Hjalmar R. Bouma"'
Autor:
Marloes M. Oosterhof, Louis Coussement, Alienke van Pijkeren, Marcel Kwiatkowski, Martijn R. H. Zwinderman, Frank J. Dekker, Tim de Meyer, Vera A. Reitsema, Rainer Bischoff, Victor Guryev, Hjalmar R. Bouma, Rob H. Henning, Marianne G. Rots
Publikováno v:
Epigenetics Communications, Vol 4, Iss 1, Pp 1-14 (2024)
Abstract Background Hibernation (torpor) is a strategy to survive extreme environmental conditions, associated with a significant decrease in metabolism and body temperature. The inducibility by the environment of torpor for facultative hibernators d
Externí odkaz:
https://doaj.org/article/69c8df83b754412d957260d7a49f95cc
Autor:
Deborah Blanca, Esther C. Schwarz, Tycho Joan Olgers, Ewoud ter Avest, Nasim Azizi, Hjalmar R. Bouma, Jan Cornelis Ter Maaten
Publikováno v:
The Ultrasound Journal, Vol 15, Iss 1, Pp 1-9 (2023)
Abstract Background Point-of-care ultrasound (POCUS) is a valuable tool for assessing the hemodynamic status of acute patients. Even though POCUS often uses a qualitative approach, quantitative measurements have potential advantages in evaluating hem
Externí odkaz:
https://doaj.org/article/6de4f278bd6d4e0685464144b40156ae
Autor:
Mohan Li, Raymond Noordam, Elizabeth M. Winter, Matijs van Meurs, Hjalmar R. Bouma, M. Sesmu Arbous, Patrick C.N. Rensen, Sander Kooijman
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115961- (2024)
Purpose: Sepsis is one of the leading causes of morbidity and mortality worldwide with approximately 50 million annual cases. There is ongoing debate on the clinical benefit of hydrocortisone in the prevention of death in septic patients. Here we eva
Externí odkaz:
https://doaj.org/article/589089edab534dfcb18b07789c92a36b
Autor:
Raymond J. van Wijk, Vincent M. Quinten, Mathilde C. van Rossum, Hjalmar R. Bouma, Jan C. ter Maaten
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol 31, Iss 1, Pp 1-11 (2023)
Abstract Background Sepsis is a life-threatening disease with an in-hospital mortality rate of approximately 20%. Physicians at the emergency department (ED) have to estimate the risk of deterioration in the coming hours or days and decide whether th
Externí odkaz:
https://doaj.org/article/45348c297dde4dc18fd497185266bbe1
Publikováno v:
Metabolites, Vol 14, Iss 3, p 162 (2024)
Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are a new class of drugs that have been proven beneficial in the management of diabetes, chronic kidney disease, and heart failure and in the mitigation of cardiovascular risk. The benefits of SGLT2
Externí odkaz:
https://doaj.org/article/edaa02884ec14a3894b69584ada768dc
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Hibernating mammals have developed many physiological adaptations to accommodate their decreased metabolism, body temperature, heart rate and prolonged immobility without suffering organ injury. During hibernation, the animals must suppress blood clo
Externí odkaz:
https://doaj.org/article/a47c8b08ef084e75b950b54e951782be
Autor:
José Castela Forte, Hubert E. Mungroop, Fred de Geus, Maureen L. van der Grinten, Hjalmar R. Bouma, Ville Pettilä, Thomas W. L. Scheeren, Maarten W. N. Nijsten, Massimo A. Mariani, Iwan C. C. van der Horst, Robert H. Henning, Marco A. Wiering, Anne H. Epema
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Despite having a similar post-operative complication profile, cardiac valve operations are associated with a higher mortality rate compared to coronary artery bypass grafting (CABG) operations. For long-term mortality, few predictors are kno
Externí odkaz:
https://doaj.org/article/9336156248a1408d8a4dc57b72808a9b
Autor:
Bastiaan S. Star, Elisabeth C. van der Slikke, Azuwerus van Buiten, Robert H. Henning, Hjalmar R. Bouma
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6330 (2023)
Sepsis is defined as a dysregulated host response leading to organ dysfunction, which may ultimately result in the patient’s death. Mitochondrial dysfunction plays a key role in developing organ dysfunction in sepsis. In this study, we explored the
Externí odkaz:
https://doaj.org/article/db40855bcb2b4e609cc7606d11172566
Autor:
Bastiaan S. Star, Elisabeth C. van der Slikke, Céline Ransy, Alain Schmitt, Robert H. Henning, Frédéric Bouillaud, Hjalmar R. Bouma
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 587 (2023)
The protective effects of hydrogen sulphide (H2S) to limit oxidative injury and preserve mitochondrial function during sepsis, ischemia/reperfusion, and neurodegenerative diseases have prompted the development of soluble H2S-releasing compounds such
Externí odkaz:
https://doaj.org/article/73bdc519bea842c7a3e83a8818233428
Autor:
Elisabeth C. van der Slikke, Bastiaan S. Star, Matijs van Meurs, Robert H. Henning, Jill Moser, Hjalmar R. Bouma
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-13 (2021)
Abstract Background Sepsis is a life-threatening condition accompanied by organ dysfunction subsequent to a dysregulated host response to infection. Up to 60% of patients with sepsis develop acute kidney injury (AKI), which is associated with a poor
Externí odkaz:
https://doaj.org/article/39847222904046838e8328df26450872