Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Hjalmar Brismar"'
Autor:
Paloma García Casas, Michela Rossini, Linnea Påvénius, Mezida Saeed, Nikita Arnst, Sonia Sonda, Tânia Fernandes, Irene D’Arsiè, Matteo Bruzzone, Valeria Berno, Andrea Raimondi, Maria Livia Sassano, Luana Naia, Elisa Barbieri, Sara Sigismund, Patrizia Agostinis, Mattia Sturlese, Barbara A. Niemeyer, Hjalmar Brismar, Maria Ankarcrona, Arnaud Gautier, Paola Pizzo, Riccardo Filadi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Membrane contact sites (MCSs) are hubs allowing various cell organelles to coordinate their activities. The dynamic nature of these sites and their small size hinder analysis by current imaging techniques. To overcome these limitations, we h
Externí odkaz:
https://doaj.org/article/0b6b5bb0acb9468497829472faf67a2f
Autor:
Kohei Otomo, Takaki Omura, Yuki Nozawa, Steven J. Edwards, Yukihiko Sato, Yuri Saito, Shigehiro Yagishita, Hitoshi Uchida, Yuki Watakabe, Kiyotada Naitou, Rin Yanai, Naruhiko Sahara, Satoshi Takagi, Ryohei Katayama, Yusuke Iwata, Toshiro Shiokawa, Yoku Hayakawa, Kensuke Otsuka, Haruko Watanabe-Takano, Yuka Haneda, Shigetomo Fukuhara, Miku Fujiwara, Takenobu Nii, Chikara Meno, Naoki Takeshita, Kenta Yashiro, Juan Marcelo Rosales Rocabado, Masaru Kaku, Tatsuya Yamada, Yumiko Oishi, Hiroyuki Koike, Yinglan Cheng, Keisuke Sekine, Jun-ichiro Koga, Kaori Sugiyama, Kenichi Kimura, Fuyuki Karube, Hyeree Kim, Ichiro Manabe, Tomomi Nemoto, Kazuki Tainaka, Akinobu Hamada, Hjalmar Brismar, Etsuo A. Susaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Despite widespread adoption of tissue clearing techniques in recent years, poor access to suitable light-sheet fluorescence microscopes remains a major obstacle for biomedical end-users. Here, we present descSPIM (desktop-equipped SPIM for c
Externí odkaz:
https://doaj.org/article/95dd009f5a8b43a5ace8ca6748af01ea
Autor:
Anna Kouznetsova, Sonata Valentiniene, Jian-Guo Liu, Tomoya S. Kitajima, Hjalmar Brismar, Christer Höög
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Correct chromosome segregation is essential to preserve genetic integrity. The two protein kinases, Aurora B and its meiotic homolog Aurora C, regulate attachments between chromosomal kinetochores and microtubules, thereby contributing to the accurac
Externí odkaz:
https://doaj.org/article/c682a469ba3248ec81f3677b7768f607
Autor:
Marlena Zyśk, Chiara Beretta, Luana Naia, Abdulkhalek Dakhel, Linnea Påvénius, Hjalmar Brismar, Maria Lindskog, Maria Ankarcrona, Anna Erlandsson
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Astrocytes play a central role in maintaining brain energy metabolism, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous studies demonstrate that inflammatory astrocytes accumulate larg
Externí odkaz:
https://doaj.org/article/6081aef51d4745efaada9dabbfba60ec
Autor:
Kristoffer Bernhem, Jacopo M. Fontana, Daniel Svensson, Liang Zhang, Linnéa M. Nilsson, Lena Scott, Hans Blom, Hjalmar Brismar, Anita Aperia
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Abstract Activation of the apoptotic pathway is a major cause of progressive loss of function in chronic diseases such as neurodegenerative and diabetic kidney diseases. There is an unmet need for an anti-apoptotic drug that acts in the early stage o
Externí odkaz:
https://doaj.org/article/ec140f73c0994590a2251ae91cdd3677
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background In the airways, mast cells are present in close vicinity to epithelial cells, and they can interact with each other via multiple factors, including extracellular vesicles (EVs). Mast cell-derived EVs have a large repertoire of car
Externí odkaz:
https://doaj.org/article/bfd3d6e5ca7d412c86a0956d1703b823
Autor:
Henrik J. Johansson, Fabio Socciarelli, Nathaniel M. Vacanti, Mads H. Haugen, Yafeng Zhu, Ioannis Siavelis, Alejandro Fernandez-Woodbridge, Miriam R. Aure, Bengt Sennblad, Mattias Vesterlund, Rui M. Branca, Lukas M. Orre, Mikael Huss, Erik Fredlund, Elsa Beraki, Øystein Garred, Jorrit Boekel, Torill Sauer, Wei Zhao, Silje Nord, Elen K. Höglander, Daniel C. Jans, Hjalmar Brismar, Tonje H. Haukaas, Tone F. Bathen, Ellen Schlichting, Bjørn Naume, Consortia Oslo Breast Cancer Research Consortium (OSBREAC), Torben Luders, Elin Borgen, Vessela N. Kristensen, Hege G. Russnes, Ole Christian Lingjærde, Gordon B. Mills, Kristine K. Sahlberg, Anne-Lise Børresen-Dale, Janne Lehtiö
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Gene expression profiles can classify breast cancer into five clinically relevant subtypes. Here, the authors perform an in-depth quantitative profiling of the proteome of 45 breast tumors, and show they can recapitulate the transcriptome-based class
Externí odkaz:
https://doaj.org/article/6d38d3e496e94ae593fe7bedce5833e0
Autor:
Steven J. Edwards, Valentina Carannante, Kyra Kuhnigk, Henrik Ring, Tatsiana Tararuk, Finn Hallböök, Hans Blom, Björn Önfelt, Hjalmar Brismar
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Three-dimensional cell cultures are able to better mimic the physiology and cellular environments found in tissues in vivo compared to cells grown in two dimensions. In order to study the structure and function of cells in 3-D cultures, light microsc
Externí odkaz:
https://doaj.org/article/b1b5d004a9df4a419da27b2e91073e2d
Autor:
Kristoffer Bernhem, Kalaiselvan Krishnan, Alexander Bondar, Hjalmar Brismar, Anita Aperia, Lena Scott
Publikováno v:
BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Blockers of angiotensin II type 1 receptor (AT1R) and the voltage gated calcium channel 1.2 (CaV1.2) are commonly used for treatment of hypertension. Yet there is little information about the effect of physiological concentrations
Externí odkaz:
https://doaj.org/article/0c816f850c66470789d862d4eaedb471
Autor:
Steven Edwards, Sebastian Bauer, Philipp Graef, Birthe Meineke, Simon Elsässer, Hjalmar Brismar
Publikováno v:
Physiology. 38
Recent developments in expansion microscopy and techniques for site-specific fluorescent labeling of proteins opens new possibilities to study nano-scale protein distributions. We have studied the spatial distribution of Na, K-ATPase alpha and beta s