Aortic distensibility alterations in adults with m.3243A>G MELAS gene mutation

Autor: A Nemes, ML Geleijnse, W Sluiter, TC Vydt, OI Soliman, WB Vletter, HJ Smeets, Coo de, Dalen van, Cate ten

Publikováno v: Swiss Medical Weekly, Vol 139, Iss 0708 (2009)

Externí odkaz: https://doaj.org/article/da9fd3dacbad4a74b22effc99a2fef11

X-Inactivation patterns in females harboring mtDNA mutations that cause Leber hereditary optic neuropathy

Autor: Hudson G, Carelli V, Horvath R, Zeviani M, Hj, Smeets, Patrick Chinnery

Publikováno v: Scopus-Elsevier
Europe PubMed Central
CIÊNCIAVITAE

Purpose: Leber hereditary optic neuropathy (LHON) is a common cause of genetically determined blindness in young adults. LHON preferentially affects males and is primarily due to a mutation affecting complex I genes of mitochondrial DNA (mtDNA). Whil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b82f6965429f0454ed905ae9678d998b
http://hdl.handle.net/11577/3354321

Wnt7a Decreases Brain Endothelial Barrier Function Via β-Catenin Activation.

Autor: Manukjan N; Department of Pharmacology and Toxicology, Maastricht University, 50 Universiteitssingel, P.O. Box 616, Maastricht, 6200 MD, The Netherlands.; CARIM-School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands.; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK., Chau S; Department of Pharmacology and Toxicology, Maastricht University, 50 Universiteitssingel, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Caiment F; Department of Toxicogenomics, GROW - School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., van Herwijnen M; Department of Toxicogenomics, GROW - School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Smeets HJ; Department of Toxicogenomics, GROW - School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands., Fulton D; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK., Ahmed Z; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, B15 2TT, Birmingham, UK. z.ahmed.1@bham.ac.uk.; Centre for Trauma Sciences Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. z.ahmed.1@bham.ac.uk., Blankesteijn WM; Department of Pharmacology and Toxicology, Maastricht University, 50 Universiteitssingel, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. wm.blankesteijn@maastrichtuniversity.nl.; CARIM-School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. wm.blankesteijn@maastrichtuniversity.nl., Foulquier S; Department of Pharmacology and Toxicology, Maastricht University, 50 Universiteitssingel, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. s.foulquier@maastrichtuniversity.nl.; CARIM-School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. s.foulquier@maastrichtuniversity.nl.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, Maastricht, 6200 MD, The Netherlands. s.foulquier@maastrichtuniversity.nl.; Department of Neurology, Maastricht University Medical Center+, P.O. Box 5800, Maastricht, 6202 AZ, The Netherlands. s.foulquier@maastrichtuniversity.nl.

Publikováno v: Molecular neurobiology [Mol Neurobiol] 2024 Jul; Vol. 61 (7), pp. 4854-4867. Date of Electronic Publication: 2023 Dec 26.

Virus-Associated CD8 ⁺ T-Cells Are Not Activated Through Antigen-Mediated Interaction Inside Atherosclerotic Lesions.

Autor: de Jong MJM; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., Schaftenaar FH; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., Depuydt MAC; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., Lozano Vigario F; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., Janssen GMC; Department of Immunology, Leiden University Medical Centre, Center for Proteomics and Metabolomics, the Netherlands (G.M.C.J., P.v.V.)., Peeters JAHM; Department of Surgery, Haaglanden Medical Center - location Westeinde, Lijnbaan, The Hague, the Netherlands (J.A.H.M.P., L.G., A.W., H.J.S.)., Goncalves L; Department of Surgery, Haaglanden Medical Center - location Westeinde, Lijnbaan, The Hague, the Netherlands (J.A.H.M.P., L.G., A.W., H.J.S.)., Wezel A; Department of Surgery, Haaglanden Medical Center - location Westeinde, Lijnbaan, The Hague, the Netherlands (J.A.H.M.P., L.G., A.W., H.J.S.)., Smeets HJ; Department of Surgery, Haaglanden Medical Center - location Westeinde, Lijnbaan, The Hague, the Netherlands (J.A.H.M.P., L.G., A.W., H.J.S.)., Kuiper J; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., Bot I; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.)., van Veelen P; Department of Immunology, Leiden University Medical Centre, Center for Proteomics and Metabolomics, the Netherlands (G.M.C.J., P.v.V.)., Slütter B; Leiden Academic Centre for Drug Research, Division of BioTherapeutics, Leiden University, the Netherlands (M.J.M.J., F.H.S., M.A.C.D., F.L.V., J.K., I.B., B.S.).

Publikováno v: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2024 Jun; Vol. 44 (6), pp. 1302-1314. Date of Electronic Publication: 2024 Mar 21.

Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment.

Autor: Manukjan N; Department of Pharmacology and Toxicology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Majcher D; Department of Pharmacology and Toxicology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Leenders P; Department of Pharmacology and Toxicology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Caiment F; Department of Toxicogenomics, GROW-School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., van Herwijnen M; Department of Toxicogenomics, GROW-School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Smeets HJ; Department of Toxicogenomics, GROW-School for Oncology and Developmental Biology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Suidgeest E; C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, P.O. Box 9500, 2300 RA, Leiden, the Netherlands., van der Weerd L; C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, P.O. Box 9500, 2300 RA, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, P.O. Box 9500, 2300 RA, Leiden, The Netherlands., Vanmierlo T; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Neuroscience, Biomedical Research Institute, Hasselt University, 3500, Hasselt, Belgium.; Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Jansen JFA; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands., Backes WH; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands., van Oostenbrugge RJ; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center+, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands., Staals J; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center+, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands., Fulton D; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK., Ahmed Z; Neuroscience and Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. z.ahmed.1@bham.ac.uk.; Centre for Trauma Sciences Research, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK. z.ahmed.1@bham.ac.uk., Blankesteijn WM; Department of Pharmacology and Toxicology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands., Foulquier S; Department of Pharmacology and Toxicology, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; CARIM - School for Cardiovascular Diseases, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; MHeNs-School for Mental Health and Neuroscience, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.; Department of Neurology, Maastricht University Medical Center+, P.O. Box 5800, 6202 AZ, Maastricht, The Netherlands.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2023 Aug 07; Vol. 11 (1), pp. 128. Date of Electronic Publication: 2023 Aug 07.