A comparison of three free and total PSA assays

Autor: MK Brawer, SC Stewart, HJ Roth

Publikováno v: Prostate Cancer and Prostatic Diseases. 1:326-331

Prostate-specific antigen (PSA) has emerged as the most predictive test of whether or not a man has prostatic carcinoma. The free to total PSA ratio provides important enhancement in specificity, thus obviating unnecessary negative biopsies. In the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685f257cba6fa6843ba5423efed23055
https://doi.org/10.1038/sj.pcan.4500264

Comparison of the role of endothelin, vasopressin and angiotensin in arterial pressure regulation during sevoflurane anaesthesia in dogs

Autor: Thomas Scheeren, J. Greve, HJ Roth, Olaf Picker, Lothar A. Schwarte

Publikováno v: British Journal of Anaesthesia, 92(1), 102-108. Oxford University Press
Picker, O, Schwarte, L A, Roth, H J, Greve, J & Scheeren, T W L 2004, ' Comparison of the role of endothelin, vasopressin and angiotensin in arterial pressure regulation during sevoflurane anaesthesia in dogs ', British Journal of Anaesthesia, vol. 92, no. 1, pp. 102-108 . https://doi.org/10.1093/bja/aeh025

Background. In this study we aimed to clarify the role of endothelin in arterial pressure regulation during anaesthesia with increasing concentrations of sevoflurane (1-3 MAC) and compare it with those of vasopressin and angiotensin. Methods. After a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692f5696d8890e2a396cc8d34f6c3259
https://research.vumc.nl/en/publications/8121347e-e397-489d-b2ff-fc496fbdbd01

Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes.

Autor: Linker SM; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Schellhaas C; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Kamenik AS; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Veldhuizen MM; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Waibl F; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Roth HJ; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Fouché M; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Rodde S; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Riniker S; Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2023 Feb 23; Vol. 66 (4), pp. 2773-2788. Date of Electronic Publication: 2023 Feb 10.

Effect of Flexibility, Lipophilicity, and the Location of Polar Residues on the Passive Membrane Permeability of a Series of Cyclic Decapeptides.

Autor: Wang S; Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., König G; Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland., Roth HJ; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Fouché M; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Rodde S; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Novartis Campus, 4056 Basel, Switzerland., Riniker S; Laboratory of Physical Chemistry, ETH Zürich, Vladimir-Prelog-Weg 2, 8093 Zürich, Switzerland.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Sep 09; Vol. 64 (17), pp. 12761-12773. Date of Electronic Publication: 2021 Aug 18.

Rationalization of the Membrane Permeability Differences in a Series of Analogue Cyclic Decapeptides.

Autor: Witek J; Laboratory of Physical Chemistry , ETH Zürich , Vladimir-Prelog-Weg 2 , 8093 Zürich , Switzerland., Wang S; Laboratory of Physical Chemistry , ETH Zürich , Vladimir-Prelog-Weg 2 , 8093 Zürich , Switzerland., Schroeder B; Laboratory of Physical Chemistry , ETH Zürich , Vladimir-Prelog-Weg 2 , 8093 Zürich , Switzerland., Lingwood R; Laboratory of Physical Chemistry , ETH Zürich , Vladimir-Prelog-Weg 2 , 8093 Zürich , Switzerland., Dounas A; Laboratory of Physical Chemistry , ETH Zürich , Vladimir-Prelog-Weg 2 , 8093 Zürich , Switzerland., Roth HJ; Novartis Institutes for BioMedical Research , Novartis Pharma AG, Novartis Campus , 4056 Basel , Switzerland., Fouché M; Novartis Institutes for BioMedical Research , Novartis Pharma AG, Novartis Campus , 4056 Basel , Switzerland., Blatter M; Novartis Institutes for BioMedical Research , Novartis Pharma AG, Novartis Campus , 4056 Basel , Switzerland., Lemke O; Department of Biology, Chemistry, Pharmacy , Freie Universität Berlin , Takustrasse 3 , 14195 Berlin , Germany., Keller B; Department of Biology, Chemistry, Pharmacy , Freie Universität Berlin , Takustrasse 3 , 14195 Berlin , Germany., Riniker S; Department of Biology, Chemistry, Pharmacy , Freie Universität Berlin , Takustrasse 3 , 14195 Berlin , Germany.

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2019 Jan 28; Vol. 59 (1), pp. 294-308. Date of Electronic Publication: 2018 Dec 04.