Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hiwa O. Ahmad"'
Autor:
Rozh Q. Ameen, Zahra A. Amin, Hiwa O. Ahmad, Diler D. Ghafur, Melodya G. Toma, Nyan Sabah, Muhammad Fakhir, Gardoon Abdulla
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract In recent times, the methods used to evaluate gastric ulcer healing worldwide have been based on visual examinations and estimating ulcer dimensions in experimental animals. In this study, the protective effect of rhodanine and 2,4-thiazolid
Externí odkaz:
https://doaj.org/article/e1e07bd7444a4dda965da02dfad7e13d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract In the present study, the hepatoprotective effect of 5-benzylidine-2-thiohydantoin (5B2T), a unique derivative of the thiohydantoin group, on liver injury induced by diethylnitrosamine (DEN) in male rats was investigated. The experimental an
Externí odkaz:
https://doaj.org/article/4f7690a92bf8490780101b4ff193b402
Autor:
Hiwa O. Ahmad, Dashti Hadi Hamad, Zanko Hasssan Jawhar, Kezhal M. Salih, Sarbast Muhammed Ahmed
Publikováno v:
Zanco Journal of Medical Sciences, Vol 23, Iss 2, Pp 206-216 (2019)
Background and objective: Compounds having imine or azomethine (–C=N–) functional group are known as Schiff bases. Schiff bases compounds are found to be an active pharmacophore for the design and development of various bioactive lead compounds.
Publikováno v:
Science Journal of University of Zakho, Vol 6, Iss 4, Pp 150-154 (2018)
The title compounds with different 5-substituted imidazolidine-2,4-dione were synthesized through a solvent-free reaction. Imidazolidine-2,4-dione derivatives are found to be an active pharmacophore for design and development of various bioactive lea
Autor:
Adam, Nelson, Robert J, Phipps, Georgie J, Crane, Niccolo A E, Venanzi, William J S, Lockley, Matthew, Tredwell, Niklaas J, Buurma, Andrew, Ballard, Hiwa O, Ahmad, Stefania, Narduolo, Lucy, Rosa, Nikki, Chand, David A, Cosgrove, Peter, Varkonyi, Nabil, Asaad, Simone, Tomasi, Andrew G, Leach, Nick, Summerhill, Jon, Bloom, Mark, Newby, Stephen, Madden, Daniela, Roman, Ruediger M, Exner, Fernando, Cortezon-Tamarit, Haobo, Ge, Stephen, Paisey, Sofia I, Pascu, Rafael T M, de Rosales, Helen C, Hailes, Yu, Wang, Jianxiong, Zhao, Daniel, Méndez-Sánchez, Rebecca, Rodan, Fabiana, Subrizi, Benjamin R, Lichman, Nicholas H, Keep, John M, Ward, Mark, Harris, Martin, Lamb, Vernon, Wilson, Peter, Iafrate, Flaviu, Bulat, Andre A, Néves, Friederike, Hesse, De-En, Hu, Franklin, Aigbirhio, Finian J, Leeper, Kevin M, Brindle, Jack S, Rowbotham, Koji, Urata, Holly A, Reeve, Kylie A, Vincent, Rebekka, Hueting
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals.
Autor:
Stefania Narduolo, Hiwa O. Ahmad, David A. Cosgrove, Niklaas J. Buurma, Andrew G. Leach, Andrew Ballard
Publikováno v:
Ballard, A, Narduolo, S, Ahmad, H O, Cosgrove, D A, Leach, A G & Buurma, N J 2019, ' The problem of racemization in drug discovery and tools to predict it ', Expert Opinion on Drug Discovery, vol. 14, no. 6, pp. 527-539 . https://doi.org/10.1080/17460441.2019.1588881
Introduction: Racemization has long been an ignored risk in drug development, probably because of a lack of convenient access to good tools for its detection and an absence of methods to predict racemization risk. As a result, the potential effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9cc162a6c5b257365cd0f71a71e91db
Autor:
Andrew G. Leach, Stefania Narduolo, Niklaas J. Buurma, Hiwa O. Ahmad, Simone Tomasi, Andrew Ballard, Nikki Chand, Peter Varkonyi, David A. Cosgrove, Nabil Asaad, Lucy Rosa
Publikováno v:
Angewandte Chemie (International Ed. in English)
Racemization has a large impact upon the biological properties of molecules but the chemical scope of compounds with known rate constants for racemization in aqueous conditions was hitherto limited. To address this remarkable blind spot, we have meas