Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hiwa K. Saeed"'
Autor:
Hiwa K. Saeed, Yogesh Sutar, Pratikkumar Patel, Roopal Bhat, Sudipta Mallick, Alyssa E. Hatada, Dana-Lynn T. Koomoa, Ingo Lange, Abhijit A. Date
Publikováno v:
ACS Omega, Vol 6, Iss 4, Pp 2626-2637 (2021)
Externí odkaz:
https://doaj.org/article/ff5bb18a6b214e9f96e2ef29257f5d64
Autor:
Pratikkumar Patel, Alyssa E. Hatada, Dana-Lynn T. Koomoa, Roopal Bhat, Hiwa K. Saeed, Ingo Lange, Sudipta Mallick, Yogesh B. Sutar, Abhijit A. Date
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 4, Pp 2626-2637 (2021)
ACS Omega, Vol 6, Iss 4, Pp 2626-2637 (2021)
Epidemiological evidence has accentuated the repurposing of metformin hydrochloride for cancer treatment. However, the extreme hydrophilicity and poor permeability of metformin hydrochloride are responsible for its poor anticancer activity in vitro a
Autor:
Anthony J. H. M. Meijer, Dimitri Chekulaev, Carl Smythe, Simon P Foxon, Sreejesh Sreedharan, Hiwa K. Saeed, Paul J. Jarman, Jorge Bernardino de la Serna, Alexander J. Auty, Julia A. Weinstein, Stuart A. Archer, Simon D Fairbanks, Theo Keane, Jim A. Thomas
Publikováno v:
Journal of the American Chemical Society. 142:1101-1111
The synthesis of new dinuclear complexes containing linked RuII(dppz) and ReI(dppz) moieties is reported. The photophysical and biological properties of the new complex, which incorporates a N,N'-bis(4-pyridylmethyl)-1,6-hexanediamine tether ligand,
Publikováno v:
Parasitology
Angiostrongylus cantonensis is the leading cause of eosinophilic meningitis worldwide, with life-threatening complications if not managed correctly. Previous in vitro studies have utilized change in motility patterns of adult female worms to assess t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb0405a1a963066f892dcdf6f297709
https://europepmc.org/articles/PMC8173162/
https://europepmc.org/articles/PMC8173162/
Autor:
Hiwa K, Saeed, Sreejesh, Sreedharan, Paul J, Jarman, Stuart A, Archer, Simon D, Fairbanks, Simon P, Foxon, Alexander J, Auty, Dimitri, Chekulaev, Theo, Keane, Anthony J H M, Meijer, Julia A, Weinstein, Carl G W, Smythe, Jorge, Bernardino de la Serna, Jim A, Thomas
Publikováno v:
Journal of the American Chemical Society. 142(2)
The synthesis of new dinuclear complexes containing linked Ru
Autor:
Firoj Ali, Amitava Das, Hiwa K. Saeed, Jim A. Thomas, Sreejesh Sreedharan, Sunil Aute, H A Anila, Carl Smythe
Publikováno v:
Chemical Communications. 54:1849-1852
BODIPY derivative, SF-1, exclusively shows a fluorescence ON response to HOCl and images endogenously generated HOCl in RAW 264.7 macrophages. Widefield and super resolution structured illumination microscopy images confirm localization in the Golgi
Autor:
Carl Smythe, Jim A. Thomas, Anila Hoskere Ashoka, Sreejesh Sreedharan, Amitava Das, Firoj Ali, Hiwa K. Saeed
Publikováno v:
Analytical Chemistry. 89:12087-12093
Selective detection of nitroxyl (HNO), which has recently been identified as a reactive nitrogen species, is a challenging task. We report a BODIPY-based luminescence ON reagent for detection of HNO in aqueous solution and in live RAW 264.7 cells, ba
Publikováno v:
Chemistry – A European Journal. 23:5467-5477
With the long-term aim of enhancing the binding properties of dinuclear RuII-based DNA light-switch complexes, a series of eight structurally related mono- and dinuclear systems are reported in which the linker of the bridging ligand has been modulat
Autor:
Isabel K Griffiths, Kirsty L. Smitten, Jim A. Thomas, Felicity F. Noakes, Carl Smythe, Paul J. Jarman, Hiwa K. Saeed, Simon D Fairbanks
Drug resistance to platinum chemotherapeutics targeting DNA often involves abrogation of apoptosis and has emerged as a significant challenge in modern, non-targeted chemotherapy. Consequently, there is great interest in the anti-cancer properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3204e2cc4d225058badf497d04d3d83c
Autor:
Kristijan Ramadan, Martin R. Gill, Carl Smythe, Hiwa K. Saeed, Jim A. Thomas, Paul J. Jarman, Michael G. Walker, Swagata Halder, Katherine A. Vallis
Publikováno v:
Chemical Science
[Ru(phen)2(tpphz)]2+ simultaneously inhibits DNA replication, blocks mitosis and enhances DNA-damaging ionising radiation in oesophageal cancer cells.
Substitutionally inert ruthenium(ii) polypyridyl complexes have been developed as DNA intercal
Substitutionally inert ruthenium(ii) polypyridyl complexes have been developed as DNA intercal