Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hiv 1 gag"'
Autor:
Elahe Akbari, Azam Bolhassani, Elnaz Agi, Soheila Ajdari, Esmat Mirabzadeh Ardakani, Vahid Khalaj
Publikováno v:
Journal of Medical Microbiology and Infectious Diseases. 9:62-70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a11a50aff9cfb00629fe06337bea19c
https://doi.org/10.52547/jommid.9.2.62
https://doi.org/10.52547/jommid.9.2.62
Publikováno v:
Cell Reports, Vol 30, Iss 12, Pp 4065-4081.e4 (2020)
Cell reports
Cell reports
SUMMARY IQGAP1 is a master regulator of many cellular processes, including intracellular vesicle trafficking and endocytosis. We show that depletion of IQGAP1 in a variety of cell types increases the release of HIV-1 infectious virions and that overe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45168186b28f311aa4459194320fe799
http://www.sciencedirect.com/science/article/pii/S2211124720303004
http://www.sciencedirect.com/science/article/pii/S2211124720303004
Autor:
Jonás Chnaiderman, Daniela Toro-Ascuy, Sebastián Riquelme-Barrios, Cecilia Rojas-Fuentes, Fernando Valiente-Echeverría, Francisco García-de-Gracia, Ricardo Soto-Rifo, Paulina Aguilera, Camila Pereira-Montecinos, Aarón Oyarzún-Arrau, Mónica Acevedo, Bárbara Rojas-Araya, Aracelly Gaete-Argel
Publikováno v:
RNA Biol
Translation initiation of the human immunodeficiency virus type-1 (HIV-1) full-length RNA has been shown to occur through cap-dependent and IRES-driven mechanisms. Previous studies suggested that the nuclear cap-binding complex (CBC) rather than eIF4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad3952e7a6e924fbad0124e98b489d9
https://europepmc.org/articles/PMC8078705/
https://europepmc.org/articles/PMC8078705/
Autor:
Simon Cocklin, Alexej Dick
Publikováno v:
Molecules, Vol 25, Iss 1687, p 1687 (2020)
Molecules
Molecules
Acquired Immune Deficiency Syndrome (AIDS) treatment with combination antiretroviral therapy (cART) has improved the life quality of many patients since its implementation. However, resistance mutations and the accumulation of severe side effects ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487e8252ccb119a95aa665e833fd7aad
https://www.mdpi.com/1420-3049/25/7/1687
https://www.mdpi.com/1420-3049/25/7/1687
Publikováno v:
Viruses
Viruses, Vol 12, Iss 394, p 394 (2020)
Volume 12
Issue 4
Viruses, Vol 12, Iss 394, p 394 (2020)
Volume 12
Issue 4
Viral genomic RNA is packaged into virions with high specificity and selectivity. However, in vitro the Gag specificity towards viral RNA is obscured when measured in buffers containing physiological salt. Interestingly, when the binding is challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea27ee93281b3381e8c81eaae2c28f87
https://pubmed.ncbi.nlm.nih.gov/32252233
https://pubmed.ncbi.nlm.nih.gov/32252233
Autor:
Tarana A Mangukia, Eduardo Reyes-Serratos, Marcelo Marcet-Palacios, Weijie Sun, Joy Ramielle L Santos
Publikováno v:
Viruses
Volume 13
Issue 8
Viruses, Vol 13, Iss 1515, p 1515 (2021)
Volume 13
Issue 8
Viruses, Vol 13, Iss 1515, p 1515 (2021)
Despite type 1 human immunodeficiency virus (HIV-1) being discovered in the early 1980s, significant knowledge gaps remain in our understanding of the superstructure of the HIV-1 matrix (MA) shell. Current viral assembly models assume that the MA she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f812ac2ffb7c64761632d3ad3775ef88
https://doi.org/10.3390/v13081515
https://doi.org/10.3390/v13081515
Publikováno v:
Molecules, Vol 24, Iss 18, p 3243 (2019)
Molecules
Molecules
HIV protease inhibitors against the viral protease are often hampered by drug resistance mutations in protease and in the viral substrate Gag. To overcome this drug resistance and inhibit viral maturation, targeting Gag alongside protease rather than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0e1d63f18ba9ddf0cfefcbc07d1d63
https://www.mdpi.com/1420-3049/24/18/3243
https://www.mdpi.com/1420-3049/24/18/3243
Autor:
Jamil S. Saad, R. Elliot Murphy
Publikováno v:
Viruses, Vol 12, Iss 548, p 548 (2020)
Viruses
Viruses
Advancement in drug therapies and patient care have drastically improved the mortality rates of HIV-1 infected individuals. Many of these therapies were developed or improved upon by using structure-based techniques, which underscore the importance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a04cdc57802de1d163ee23f2fb41612
https://doi.org/10.3390/v12050548
https://doi.org/10.3390/v12050548
Autor:
Arishma Rajkarnikar Singh, Jonathan P Kitzrow, Karin Musier-Forsyth, Raymond F. Pauszek, Shuohui Liu, David P. Millar
Publikováno v:
Biophysical Journal. 118:73a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9edd770c34a0de54b0b1db2c266279b5
https://doi.org/10.1016/j.bpj.2019.11.575
https://doi.org/10.1016/j.bpj.2019.11.575