Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hiuwan Choi"'
Autor:
Amita Datta-Mannan, Hiuwan Choi, Zhaoyan Jin, Ling Liu, Jirong Lu, David J. Stokell, Anthony T. Murphy, Kenneth W. Dunn, Michelle M. Martinez, Yiqing Feng
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/88740c93e82b4e8cb5d7edb2fd408cba
Autor:
Amita Datta-Mannan, Selina Estwick, Chen Zhou, Hiuwan Choi, Nicole E. Douglass, Derrick R. Witcher, Jirong Lu, Catherine Beidler, Rohn Millican
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the patient experience, subcutaneous (SC) administration is an increasingly important delivery rout
Externí odkaz:
https://doaj.org/article/58c5f4e8c8a14a51b74643d2b367cca2
Autor:
Trung C. Nguyen, Anne Liu, Li Liu, Chalmette Ball, Hiuwan Choi, William S. May, Khatira Aboulfatova, Angela L. Bergeron, Jing-fei Dong
Publikováno v:
Haematologica, Vol 92, Iss 1 (2007)
We studied the state of ultralarge von Willebrand factor (ULVWF) proteolysis in 21 pediatric patients with severe sepsis and found that the overall group of patients had moderately reduced ADAMTS-13 activity, but 31% had severe enzymatic deficiency.
Externí odkaz:
https://doaj.org/article/43b60f2ba4ed4a33b582312fe9d692da
Autor:
Rohn Lee Millican, Chen Zhou, Catherine Brautigam Beidler, Nicole E Douglass, Jirong Lu, Derrick R. Witcher, Amita Datta-Mannan, Selina Estwick, Hiuwan Choi
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Many therapeutic monoclonal antibodies (mAbs) were initially developed for intravenous (IV) administration. As a means to improve mAb drug-ability and the patient experience, subcutaneous (SC) administration is an increasingly important delivery rout
Autor:
Yiqing Feng, Anthony Murphy, David J. Stokell, Hiuwan Choi, Jason Tang, Amita Datta-Mannan, Wrobleski Aaron D
Publikováno v:
The AAPS journal. 20(6)
Among the numerous antibody-drug conjugate (ADC) clinical candidates, one of the most prevalent types utilizes the interchain cysteines in antibodies to conjugate auristatin via a maleimide-containing linker. In this class of ADCs, there are a paucit
Publikováno v:
Journal of Biological Chemistry. 282:35604-35611
von Willebrand factor (VWF) is the largest multimeric adhesion ligand circulating in blood. Its adhesion activity is related to multimer size, with the ultra-large forms freshly released from the activated endothelial cells being most active, capable
Autor:
Chalmette Ball, Trung C. Nguyen, Angela L. Bergeron, Jing-fei Dong, Hiuwan Choi, Anne Liu, William May, Khatira Aboulfatova, Li Liu
Publikováno v:
Haematologica. 92:121-124
We studied the state of ultra-large von Willebrand factor (ULVWF) proteolysis in 21 pediatric patients with severe sepsis and found that the overall group of patients had moderately reduced ADAMTS-13 activity, but 31% had severe enzymatic deficiency.
Autor:
Hiuwan Choi, Nancy A. Turner, William May, Joel L. Moake, Jing-fei Dong, Zhou Zhou, Senem Tekeoglu, Hui-Chun Yeh, Friedrich Scheiflinger, Christina Wang
Publikováno v:
Journal of thrombosis and haemostasis : JTH. 8(12)
See also Lenting PJ, Rastegarlari G. ADAMTS-13: double trouble for von Willebrand factor. This issue, pp 2775–7. Summary. Background: von Willebrand factor (VWF) released from endothelial cells is rich in ultra-large (UL) multimers that are intrins
Autor:
Miguel A. Cruz, Thomas A. Kent, Michael H. Kroll, Sheryl R. Martini, Cecilia Martin, Jing Fei Dong, Angela L. Bergeron, Hiuwan Choi, Khatira Aboulfatova
Publikováno v:
Thrombosis and haemostasis. 99(3)
SummaryMg ++ regulates endothelial functions and has anti-inflammatory effects. Its effects on thrombosis have been demonstrated, but the mechanism remains poorly understood.We investigated the roles of MgSO4 in regulating the release and cleavage of
Autor:
Henry J. Pownall, Leticia Nolasco, Zhou Zhou, Jan Voorberg, Ying Li, Hiuwan Choi, Joel L. Moake, Jing-fei Dong
Publikováno v:
Journal of thrombosis and haemostasis, 6(7), 1135-1143. Wiley-Blackwell
Summary. Background and Objectives: The adhesion ligand von Willebrand factor (VWF) is a multimeric glycoprotein that mediates platelet adhesion to exposed subendothelium. On endothelial cells, freshly released ultra-large (UL) VWF multimers form lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff44760da79e83bd715fbdb4c71f7d5
https://pure.amc.nl/en/publications/covalent-regulation-of-ulvwf-string-formation-and-elongation-on-endothelial-cells-under-flow-conditions(61f75aea-c1eb-4a73-9859-e0987fca99d0).html
https://pure.amc.nl/en/publications/covalent-regulation-of-ulvwf-string-formation-and-elongation-on-endothelial-cells-under-flow-conditions(61f75aea-c1eb-4a73-9859-e0987fca99d0).html