Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hitoshi Noda"'
Autor:
Masayuki Okamoto, Hitomi Tanimoto, Mitsuaki Takeuchi, Yoshiharu Tsubamoto, Takashi Nakamura, Hitoshi Noda
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Takashi Nakamura, Hitomi Tanimoto, Masayuki Okamoto, Mitsuaki Takeuchi, Yoshiharu Tsubamoto, Hitoshi Noda Biological Research Group Drug Discovery Laboratories, Sanwa Kagaku Kenkyusho, Mie, JapanCorrespondence: Takashi NakamuraSanwa Kagaku Kenkyusho,
Publikováno v:
Optical Review. 19:381-387
We propose a sweep-free measurement technique for distributed Brillouin frequency shift in optical fibers applicable to distributed strain/temperature monitoring systems, using two sets of pump-probe lights generated by two individual laser sources.
Autor:
Daniel Vitt, Kristina Wolf, Roland Baumgartner, Nobumitsu Tajima, Tokuyuki Yamashita, Viola Trentinaglia, Marcus Blisse, Andrea Aschenbrenner, Tanja Wieber, Martin Lang, Markus H.J. Seifert, Hitoshi Noda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:5417-5422
We report on a hit generation and hit-to-lead program of a novel class of glucokinase activators (GKAs). Hit compounds, activators at low glucose concentration only were identified by vHTS. Scaffold modification reliably afforded activators also at h
Publikováno v:
IUBMB Life. 40:923-929
Eel calcitonin (CT) analogues having C-terminal homoserine (Hse)-amide at position 31, 32, or 33 were synthesized, and in vivo hypocalcemic activity of the analogues were determined. The present study showed that: (i) An eel CT analogue having Hse-am
Autor:
Takafumi Iida, Kunio Yagi, Hisashi Michishita, Tomio Ogasawara, Hitoshi Noda, Hidefumi Yamakawa, Takahiko Mitani, Masayasu Kurono
Publikováno v:
Biological and Pharmaceutical Bulletin. 17:1246-1250
Ceramide sulfate (N-acylsphingosine-1-O-sulfate), which lacks the galactose residue of sulfatide, was examined as a possibly preferable constituent of liposomes for drug delivery. Multilamellar vesicles prepared from phosphatidylcholine, cholesterol,
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 10:181-188
Pharmacokinetics and antineoplastic effect of adriamycin (ADM) entrapped in multilamellar vesicles of liposomes composed of egg phosphatidylcholine (PC), cholesterol (Chol), and cholesterol sulfate (CholSO4) in a molar ratio of 6:3:1 were studied. Up
Publikováno v:
Journal of Clinical Biochemistry and Nutrition. 10:83-91
Cholesterol sulfate (CholSO4) was found to be a useful substitute of sulfatide for the preparation of negatively charged liposomes entrapping adriamycin (ADM). Liposomes composed of egg phosphatidylcholine, cholesterol, and CholSO4 in a molar ratio o
Publikováno v:
Biochimica et biophysica acta. 1153(1)
The characteristic effects of sulfatide and its derivatives on the stability of small unilamellar vesicles of egg phosphatidylcholine liposomes in phosphate-buffered saline were investigated by measuring the leakage of carboxyfluorescein that had bee
SYNTHETIC STUDIES ON ASATONE-TYPE NEOLIGNANS OXIDATION OF 4-ALLYLPHENOLS WITH THALLIUM (III) NITRATE
Publikováno v:
Chemistry Letters. 9:85-88
Oxidation of 4-allylphenols in MeOH has been carried out using thallium (III) nitrate to give two different types of reaction product. In the cases of 4-allylphenols with an electron-donating group (MeO), methoxylation takes place on the aromatic rin
Autor:
Chin-Cho Lin, Takuji Ohtsubo, Wataru Sugiyama, Hitoshi Noda, Syoichirow Kawase, Kohji Tsutsumi, Shigeru Muta, Hideyuki Tanaka, Katsuumi Yoshinari, Takayoshi Igarashi
Publikováno v:
Nihon Hotetsu Shika Gakkai Zasshi. 22:790-800