Zobrazeno 1 - 10
of 341
pro vyhledávání: '"Hitoshi Mochizuki"'
Publikováno v:
Vaccine: X, Vol 17, Iss , Pp 100433- (2024)
Background: The infection status of healthcare workers (HCWs) with coronavirus disease 2019 has become a major concern worldwide. In this study, we investigated the efficacy of the number of vaccine doses on symptoms after BA.5-adapted bivalent vacci
Externí odkaz:
https://doaj.org/article/c35c0d7cee2c44698d797dec937bbfb7
Autor:
Kenichiro Okimoto, Yosuke Hirotsu, Makoto Arai, Kenji Amemiya, Naoki Akizue, Yuki Ohta, Takashi Taida, Keiko Saito, Hiroshi Ohyama, Tomoaki Matsumura, Motoi Nishimura, Kazuyuki Matsushita, Keisuke Matsusaka, Toshio Oyama, Hitoshi Mochizuki, Tetsuhiro Chiba, Jun Kato, Jun‐ichiro Ikeda, Osamu Yokosuka, Naoya Kato, Masao Omata
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8490-8498 (2023)
Abstract Background This study aimed to investigate the validity of pathological diagnosis of early CRC (E‐CRC) from the genetic background by comparing data of E‐CRC to colorectal adenoma (CRA) and The Cancer Genome Atlas (TCGA) on advanced CRC
Externí odkaz:
https://doaj.org/article/0a05a72dd34f4bc99d4eef95784d4b12
Autor:
Kenji Amemiya, Yosuke Hirotsu, Yuki Nagakubo, Shunsuke Watanabe, Saki Amemiya, Hitoshi Mochizuki, Toshio Oyama, Tetsuo Kondo, Masao Omata
Publikováno v:
Cancer Medicine, Vol 11, Iss 23, Pp 4479-4490 (2022)
Abstract Evaluation of the status of mismatch repair (MMR) in tumors is crucial for determining the application of immune checkpoint inhibitors (ICIs). Conventional PCR (MSI‐PCR) is the gold standard for confirming the MMR status. However, it requi
Externí odkaz:
https://doaj.org/article/fa3f115448a64e74b08c9171d84662f7
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Although many studies have been conducted on the increase in spike antibody levels after vaccination, there is insufficient prospective and longitudinal information on the BA.5-adapted bivalent vaccine up to the fifth vaccination. In this st
Externí odkaz:
https://doaj.org/article/812e89ce5eba4d4da3f7d604a7dd394d
Autor:
Yosuke Hirotsu, Makoto Maejima, Masahiro Shibusawa, Yume Natori, Yuki Nagakubo, Kazuhiro Hosaka, Hitomi Sueki, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
International Journal of Infectious Diseases, Vol 122, Iss , Pp 486-491 (2022)
Objectives: Recently, the Omicron strain of SARS-CoV-2 has spread and replaced the previously dominant Delta strain. Several Omicron sublineages (BA.1, BA.1.1, and BA.2) have been identified, with in vitro and preclinical reports showing that the pat
Externí odkaz:
https://doaj.org/article/73f355ecea044d9e8c7e6d7f9b4eef26
Autor:
Yosuke Hirotsu, Makoto Maejima, Masahiro Shibusawa, Yume Natori, Yuki Nagakubo, Kazuhiro Hosaka, Hitomi Sueki, Kenji Amemiya, Miyoko Hayakawa, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The nucleic acid amplification test (NAAT) and antigen test are approved diagnostic tests for COVID-19. In this study, we aimed to investigate the assay performance of two NAATs (Xpert Xpress SARS-CoV-2 and FilmArray Respiratory P
Externí odkaz:
https://doaj.org/article/751d23150ddd423597e4705622e9b830
Autor:
Masao Omata, Yosuke Hirotsu, Hiroki Sugiura, Makoto Maejima, Yuki Nagakubo, Kenji Amemiya, Miyoko Hayakawa, Toshiharu Tsutsui, Yumiko Kakizaki, Hitoshi Mochizuki, Yoshihiro Miyashita
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 5, Pp 830-838 (2021)
Background: Currently, PCR assay is a golden standard for diagnosis of Covid-19. However, it needs nasopharyngeal swabs, expensive instruments and expertise. It even causes PCR errors. Methods: We validated the antibody assay (Roche) in 36 followed p
Externí odkaz:
https://doaj.org/article/c58044cae40143e98c5c7e8a3e240724
Autor:
Mamoru Tokunaga, Kenichiro Okimoto, Naoki Akizue, Kentaro Ishikawa, Yosuke Hirotsu, Kenji Amemiya, Masayuki Ota, Keisuke Matsusaka, Motoi Nishimura, Kazuyuki Matsushita, Tsubasa Ishikawa, Ariki Nagashima, Wataru Shiratori, Tatsuya Kaneko, Hirotaka Oura, Kengo Kanayama, Yuki Ohta, Takashi Taida, Keiko Saito, Tomoaki Matsumura, Tetsuhiro Chiba, Hitoshi Mochizuki, Makoto Arai, Jun Kato, Jun-ichiro Ikeda, Masao Omata, Naoya Kato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The genetic characteristics of Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) in the Japanese population is unclear. This study aims to investigate the genetic characteristics from nondysplastic BE (NDBE) to early EAC in Japa
Externí odkaz:
https://doaj.org/article/e213bb3c99c349dcbcdcbcd125e3cbfb
Autor:
Yosuke Hirotsu, Hiroki Sugiura, Makoto Maejima, Miyoko Hayakawa, Hitoshi Mochizuki, Toshiharu Tsutsui, Yumiko Kakizaki, Yoshihiro Miyashita, Masao Omata
Publikováno v:
International Journal of Infectious Diseases, Vol 108, Iss , Pp 263-269 (2021)
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread worldwide. Here, we evaluated the performance of two quantitative antigen (Ag) tests, the Roche and Lumipulse Ag tests, using automated platforms. Methods: W
Externí odkaz:
https://doaj.org/article/b8256eedd8aa41c2b444beb2268a1aa9
Autor:
Naoki Akizue, Kenichiro Okimoto, Makoto Arai, Yosuke Hirotsu, Kenji Amemiya, Hirotaka Oura, Tatsuya Kaneko, Mamoru Tokunaga, Kentaro Ishikawa, Yuki Ohta, Takashi Taida, Keiko Saito, Daisuke Maruoka, Tomoaki Matsumura, Tomoo Nakagawa, Motoi Nishimura, Tetsuhiro Chiba, Kazuyuki Matsushita, Hitoshi Mochizuki, Osamu Yokosuka, Masao Omata, Naoya Kato
Publikováno v:
Cancer Medicine, Vol 10, Iss 11, Pp 3545-3555 (2021)
Abstract Somatic mutations including the background mucosa in patients with Lugol‐voiding lesions (LVLs) are still not well known. The aim of this study was to evaluate the somatic mutations of the background mucosa in patients with LVLs (Squamous
Externí odkaz:
https://doaj.org/article/25119e7086a74f44bbf7ce3b4a073458