Secretory Expression of the Human Serum Albumin Gene in the Yeast, Saccharomyces cerevisiae

Autor: Ken Okabayashi, Hirabayashi Kazumoto, Yukimitsu Nakagawa, Shimizu Miho, Takao Ohmura, Masami Miura, Haruhide Kawabe, Yutaka Ishida, Hideyuki Ohi, Naofumi Hayasuke, Akinori Sumi, Atsushi Masaki, Kohji Murakami, Hajime Horii, Hitoshi Minamino

Publikováno v: The Journal of Biochemistry. 110:103-110

We have fused a cDNA gene encoding mature human serum albumin (HSA) to several secretory leader-encoding sequences. The hybrid genes were cloned into an episomal vector under the control of several yeast promoters and then introduced into yeast cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc7cd9ea965287b38c3473dae027344
https://doi.org/10.1093/oxfordjournals.jbchem.a123527

Long-term safety of Prolastin®-C, an alpha1-proteinase inhibitor, in Japanese patients with alpha1-antitrypsin deficiency.

Autor: Seyama K; Division of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan. Electronic address: kseyama@juntendo.ac.jp., Suzuki M; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Tasaka S; Department of Respiratory Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Nukiwa T; Professor Emeritus, Tohoku University, Sendai, Japan., Sato T; Division of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, Tokyo, Japan., Konno S; Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Sorrells S; Grifols Bioscience Research Group, Grifols, Research Triangle Park, NC, USA., Chen J; Grifols Bioscience Research Group, Grifols, Research Triangle Park, NC, USA., Aragonés ME; Grifols Bioscience Research Group, Grifols, Barcelona, Spain., Minamino H; Grifols Japan KK, Tokyo, Japan.

Publikováno v: Respiratory investigation [Respir Investig] 2022 Nov; Vol. 60 (6), pp. 831-839. Date of Electronic Publication: 2022 Aug 12.