Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hitoshi Kohayakawa"'
Autor:
N. Yoshida, Hitoshi Kohayakawa, K. Nakamichi, Tomoko Kinoshita, Takashi Hashimoto, T. Kiyoshi, Yuki Hatayama
Publikováno v:
Neuroscience. 265:217-225
GABAergic neurons are known to inhibit neural transduction and therefore negatively affect excitatory neural circuits in the brain. We have previously reported that 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one (AC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5cc5257617c27b979aeb245ddd638d
https://doi.org/10.1016/j.neuroscience.2014.01.063
https://doi.org/10.1016/j.neuroscience.2014.01.063
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:1040-1045
AC-5216, a ligand for the translocator protein (18 kDa) (TSPO), produces anxiolytic-like effects in animal models of anxiety without causing the side effects normally associated with conventional benzodiazepines. This study aimed to investigate wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78785096d8ec7b4f5ccad70ef71bf287
https://doi.org/10.1016/j.pnpbp.2009.05.018
https://doi.org/10.1016/j.pnpbp.2009.05.018
Autor:
Makoto Oka, Tomoko Kinoshita, Kiyoshi Furukawa, Keiko Nakamichi, Hitoshi Kohayakawa, Atsuko Kita, Yoshiaki Ochi, Kurumiya Satoshi
Publikováno v:
British Journal of Pharmacology. 142:1059-1072
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb409ed8a9ebe77280e5a07979b84a84
https://doi.org/10.1038/sj.bjp.0705681
https://doi.org/10.1038/sj.bjp.0705681
Publikováno v:
European Journal of Pharmacology. 412:171-179
In radioligand binding assays, AH-9700 (1-[2-(3,4-dihydro-6,7-dimethyl-2-naphthalenyl)ethyl]pyrrolidine fumarate) had high affinity for sigma receptors and moderate affinity for muscarinic receptors. The affinity of AH-9700 for sigma(1) receptors was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0144d10bbbd8c5f3577a87baf4fa7a6b
https://doi.org/10.1016/s0014-2999(00)00937-7
https://doi.org/10.1016/s0014-2999(00)00937-7
Autor:
Yasuji Furutani, Yuki Hatayama, Hitoshi Kohayakawa, Tomoko Kiyoshi, Naoyuki Yoshida, Takashi Hashimoto, Yoshiaki Ochi
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb509ee8f2be83c83a87aa32da37c15
https://doi.org/10.1016/j.jalz.2011.05.1879
https://doi.org/10.1016/j.jalz.2011.05.1879
Autor:
Atsuko, Kita, Hitoshi, Kohayakawa, Tomoko, Kinoshita, Yoshiaki, Ochi, Keiko, Nakamichi, Satoshi, Kurumiya, Kiyoshi, Furukawa, Makoto, Oka
Publikováno v:
British journal of pharmacology. 142(7)
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa572b3b4d0474c41c8754ab3c6fd6de
https://pubmed.ncbi.nlm.nih.gov/15249420
https://pubmed.ncbi.nlm.nih.gov/15249420
Publikováno v:
Pharmacology, biochemistry, and behavior. 52(4)
We investigated the effects of RGH-2202 {posatirelin, (−)-(2S)-N-[(1S)-1-[[(2S)-2-carbamoyl-1-pyrrolidinyl[carbonyl]-3-methylbutyl]-6-oxopipecolamide}, a thyrotropin-releasing hormone (TRH) analog, on behavioral changes during a chronic phase of fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf6b6508fa3308254149f6753269a08
https://pubmed.ncbi.nlm.nih.gov/8587907
https://pubmed.ncbi.nlm.nih.gov/8587907
Publikováno v:
Japanese Journal of Pharmacology. 79:233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7178d62a3100bfccea79c03bbc291d3d
https://doi.org/10.1016/s0021-5198(19)34946-7
https://doi.org/10.1016/s0021-5198(19)34946-7
Autor:
Yoshiaki Ochi, Fumiyo Fukuya, Hideto Noguchi, Kazuo Okimoto, Hitoshi Kohayakawa, Kanoo Hosoki, Yoshinobu Masuda
Publikováno v:
Japanese Journal of Pharmacology. 76:119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dd3a5c29baa9a0ceae710ff1a12c1d4
https://doi.org/10.1016/s0021-5198(19)40594-5
https://doi.org/10.1016/s0021-5198(19)40594-5