Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hitoshi Kamauchi"'
Autor:
Yuka Kiba, Takashi Tanikawa, Tsuyoshi Hayashi, Hitoshi Kamauchi, Taishi Seki, Ryuichiro Suzuki, Masashi Kitamura
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115940- (2023)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread as a pandemic and caused damage to people’s lives and countries’ economies. The spike (S) protein of SARS-CoV-2 contains a cleavag
Externí odkaz:
https://doaj.org/article/d6bc43699e844feaa4efbd4b38b07b89
Publikováno v:
ACS Omega, Vol 7, Iss 45, Pp 41804-41814 (2022)
Externí odkaz:
https://doaj.org/article/a8998a581c89430787f22bc8b171e1c4
Autor:
Hitoshi Kamauchi, Satoshi Hayashi, Toshikatsu Takanami, Hiroaki Sasaki, Koji Fujihara, Yoshihiro Kino, Kiyotaka Koyama, Masahiro Noji, Kaoru Kinoshita, Jun-ichi Satoh, Youki Masuda
Publikováno v:
Journal of Natural Products. 84:1748-1754
To develop drugs to treat Alzheimer's disease (AD) on the basis of the amyloid cascade hypothesis, the amyloid-β (Aβ) aggregation inhibitory activities of 110 extracts from mushrooms were evaluated by thioflavin T (Th-T) assays. The MeOH extract of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5adec94a793b00f2b3e3ad10dfe2b4f2
https://doi.org/10.1021/acs.jnatprod.0c01329
https://doi.org/10.1021/acs.jnatprod.0c01329
Autor:
Hitoshi Kamauchi, Miho Furukawa, Yuka Kiba, Masashi Kitamura, Kanako Usui, Masanori Katakura, Koichi Takao, Yoshiaki Sugita
Publikováno v:
The Journal of antibiotics. 75(9)
Cell adhesion plays a crucial role in candidiasis through invasion of the human body and obtaining resistance to drugs by forming biofilms. Cell adhesion thus is a critical target for combating candidiasis by preventing the entry of fungal hyphae int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b980e15a976d8e84433a4ea0cb5055
https://pubmed.ncbi.nlm.nih.gov/35859164
https://pubmed.ncbi.nlm.nih.gov/35859164
Publikováno v:
Chemical and Pharmaceutical Bulletin. 68:1082-1089
A series of 2-(N-cyclicamino)chromone derivatives (1a-4c) and 3-(N-cyclicamino)chromone derivatives (5a-8c) were synthesized, and their monoamine oxidase (MAO) A and B inhibitory activities were studied as part of a structure-activity relationship in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b434c4a099f086218da7f710e662b8e6
https://doi.org/10.1248/cpb.c20-00579
https://doi.org/10.1248/cpb.c20-00579
Publikováno v:
The Journal of antibiotics. 75(1)
The ribosome-targeted antifungal agent hygromycin B (HygB) alters the secondary metabolite profiles of fungi. Hypoxylon truncatum NBRC 32353 fermented in the presence of hygromycin B in barley medium activated secondary metabolite synthesis. A new be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039c21a3016f0b2bf80dfe670fedbd1d
https://pubmed.ncbi.nlm.nih.gov/34819605
https://pubmed.ncbi.nlm.nih.gov/34819605
Autor:
Youki, Masuda, Koji, Fujihara, Satoshi, Hayashi, Hiroaki, Sasaki, Yoshihiro, Kino, Hitoshi, Kamauchi, Masahiro, Noji, Jun-Ichi, Satoh, Toshikatsu, Takanami, Kaoru, Kinoshita, Kiyotaka, Koyama
Publikováno v:
Journal of natural products. 84(6)
To develop drugs to treat Alzheimer's disease (AD) on the basis of the amyloid cascade hypothesis, the amyloid-β (Aβ) aggregation inhibitory activities of 110 extracts from mushrooms were evaluated by thioflavin T (Th-T) assays. The MeOH extract of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c22fb224d90634f0fa4980902334258
https://pubmed.ncbi.nlm.nih.gov/34100599
https://pubmed.ncbi.nlm.nih.gov/34100599
Publikováno v:
Bioorganic Chemistry. 87:594-600
A series of 2-(indolylmethylidene)-2,3-dihydro-1-benzofuran-3-ones (aurone-indole hybrids) and 2-(indolyl)-4H-chromen-4-ones (flavone-indole hybrids) were designed, synthesized, and their monoamine oxidase (MAO) A and B inhibitory activities were eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0096a94b39bf8cb43ef1159f6d95d8
https://doi.org/10.1016/j.bioorg.2019.03.042
https://doi.org/10.1016/j.bioorg.2019.03.042
Publikováno v:
Bioorganic Chemistry. 83:432-437
A series of eighteen pyrano[4,3-b][1]benzopyranone derivatives (1a-9b) were synthesized, and structure-activity relationships of their monoamine oxidase (MAO) A and B, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) inhibitory activitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee4a8e1a9a88bfe65c167a4eca5f8d2
https://doi.org/10.1016/j.bioorg.2018.11.004
https://doi.org/10.1016/j.bioorg.2018.11.004
Autor:
Junko Nagai, Hitoshi Kamauchi, Kaori Hoshi, Koichi Takao, Yuri Takemura, Ryo Mabashi, Yoshiaki Sugita, Yoshihiro Uesawa
Publikováno v:
Bioorganicmedicinal chemistry. 42
A series of 3-styrylchromone derivatives was synthesized and evaluated for monoamine oxidase (MAO) A and B inhibitory activities. Most of all derivatives inhibited MAO-B selectively, except compound 21. Compound 19, which had a methoxy group at R2 on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e0a14ed34adc05f70a9e445d793bc54
https://pubmed.ncbi.nlm.nih.gov/34119696
https://pubmed.ncbi.nlm.nih.gov/34119696