Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hitoshi Houchigai"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:601-621
A series of 1β-methylcarbapenems containing variously C-2 substituted thiazol-2-ylthio groups were synthesized, and their in vitro anti-MRSA activity was examined. Among them, 1β-methyl-2-(4-arylthiazol-2-ylthio) carbapenems exhibited superior anti
Publikováno v:
Bulletin of the Chemical Society of Japan. 66:848-856
α-(Sulfenylmethyl)allyl acetates reacted with silylated carbon nucleophiles in the presence of a catalytic amount of TMSOTf to give products substituted at the α-position of the sulfenylmethyl group in moderate to good yields with high regioselecti
Publikováno v:
ChemInform. 23
(α-Sulfenylmethyl)allyl acetates reacted with silylated carbon nucleophiles in the presence of a catalytic amount of a Lewis acid to give mainly α-adducts at the sulfenylmethyl group in moderate to good yields with high regioselectivity. The reacti
Publikováno v:
ChemInform. 26
Synthesis and biological properties of a new series of 1β-methyl carbapenems that have been variously substituted thiazol-2′-ylthio side chain on C-2 are described. Amongst synthesized compounds, 4′-arylthiazole derivatives showed potent anti-MR
Publikováno v:
Tetrahedron Letters. 33:3145-3146
Copper(I) catalyzed conjugate addition of Grignard reagents to the title compound (1c) proceeded in good to high diastereoselectivity.
Publikováno v:
Tetrahedron Letters. 32:4311-4312
(α-Sulfenylmethyl)allyl acetates reacted with silylated carbon nucleophiles in the presence of a catalytic amount of a Lewis acid to give mainly α-adducts at the sulfenylmethyl group in moderate to good yields with high regioselectivity. The reacti