Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Hitoshi, Sakaguchi"'
Autor:
Akira Ogasawara, Takuo Yuki, Asuka Katagiri, Yi-Ting Lai, Yutaka Takahashi, David Basketter, Hitoshi Sakaguchi
Publikováno v:
Journal of Immunotoxicology, Vol 19, Iss 1, Pp 27-33 (2022)
Epicutaneous exposure to protein allergens, such as papain, house dust mite (HDM), and ovalbumin (OVA), represents an important mode of sensitization for skin diseases including protein contact dermatitis, immunologic contact urticaria, and atopic de
Externí odkaz:
https://doaj.org/article/77b92c67cab143289e3dd4f890733bc7
Autor:
Kristine A. Lacek, Benjamin L. Rambo-Martin, Dhwani Batra, Xiao-yu Zheng, Norman Hassell, Hitoshi Sakaguchi, Thomas Peacock, Natalie Groves, Matthew Keller, Malania M. Wilson, Mili Sheth, Morgan L. Davis, Mark Borroughs, Jonathan Gerhart, Samuel S. Shepard, Peter W. Cook, Justin Lee, David E. Wentworth, John R. Barnes, Rebecca Kondor, Clinton R. Paden
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 7, Pp 1442-1445 (2022)
To detect new and changing SARS-CoV-2 variants, we investigated candidate Delta–Omicron recombinant genomes from Centers for Disease Control and Prevention national genomic surveillance. Laboratory and bioinformatic investigations identified and va
Externí odkaz:
https://doaj.org/article/5e8324ff95a14c0798f9d40af5b9161c
Autor:
Hajime Kojima, Tokio Nakada, Akiko Yagami, Hiroaki Todo, Jihei Nishimura, Mio Yagi, Keiko Yamamoto, Mariko Sugiyama, Yoshiaki Ikarashi, Hitoshi Sakaguchi, Masahiko Yamaguchi, Morihiko Hirota, Sakiko Aizawa, Shota Nakagawa, Shigenobu Hagino, Masato Hatao
Publikováno v:
Current Research in Toxicology, Vol 4, Iss , Pp 100100- (2023)
Animal testing of cosmetic ingredients and products has been banned in the European Union since 2013. However, in Japan, the application of new quasi-drugs requires the generation of data on acute oral toxicity through animal testing. A weight of evi
Externí odkaz:
https://doaj.org/article/87dee5b26ae9496ab51c2bcc9ad2ae5d
Autor:
Akira Ogasawara, Takuo Yuki, Toshiro Takai, Kyosuke Yokozeki, Asuka Katagiri, Yutaka Takahashi, Hiroo Yokozeki, David Basketter, Hitoshi Sakaguchi
Publikováno v:
Journal of Immunotoxicology, Vol 18, Iss 1, Pp 118-126 (2021)
Epicutaneous exposure to allergenic proteins is an important sensitization route for skin diseases like protein contact dermatitis, immunologic contact urticaria, and atopic dermatitis. Environmental allergen sources such as house dust mites contain
Externí odkaz:
https://doaj.org/article/d40ce699ab904979b21f3184f4a7ba18
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 4, Pp 629-637 (2020)
Abstract Introduction Mechanisms underlying skin sensitization in allergic contact dermatitis have been actively studied using the murine contact hypersensitivity (CHS) model. However, much less is known about sensitization at the vaginal mucosa (VM)
Externí odkaz:
https://doaj.org/article/a510fcef61d04c9e84d61006b304588b
Autor:
Kanako Nakayama, Taku Nishijo, Masaaki Miyazawa, Tetsuro Watabe, Miyuki Azuma, Hitoshi Sakaguchi
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Introduction Contact hypersensitivity (CHS), a type of delayed‐type hypersensitivity, is induced by hapten exposure to the skin and mucosa. We previously reported that, in a murine model of CHS, the vaginal mucosa (VM) sensitization showed
Externí odkaz:
https://doaj.org/article/c44f130575754963ba8a1e45165eb16b
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1370 (2022)
Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M®, has been focused on as the tool which could obtain the permeation parameters
Externí odkaz:
https://doaj.org/article/0776f89ecfa44cbaa9a85d0df19a6b02
Autor:
Takayuki Abo, Yuuki Deguchi, Takuo Yuki, Yutaka Takahashi, Masaaki Miyazawa, Hitoshi Sakaguchi
Publikováno v:
The Journal of Toxicological Sciences. 48:363-374
Autor:
Daisaku Kimura, Teruyo Kida, Takaki Sato, Masanori Fukumoto, Ryohsuke Kohmoto, Shota Kojima, Hiroshi Mizuno, Hitoshi Sakaguchi, Jun Sugasawa, Tsunehiko Ikeda
Publikováno v:
Case Reports in Ophthalmology, Vol 9, Iss 1, Pp 17-23 (2018)
Purpose: To report a case of retinal detachment with unique optical coherence tomography (OCT) findings after Gamma Knife® (GK; Elekta Instrument AB, Stockholm, Sweden) treatment for choroidal melanoma (CM). Case Report: A 48-year-old woman underwen
Externí odkaz:
https://doaj.org/article/8304a7d26e9f4652a86194affc323b5e
Autor:
Yasutaka Kuroda, Takuo Yuki, Yutaka Takahashi, Hitoshi Sakaguchi, Kayoko Matsunaga, Hiroshi Itagaki
Publikováno v:
Journal of Immunotoxicology, Vol 14, Iss 1, Pp 178-187 (2017)
A growing body of evidence suggests that epicutaneous sensitization of protein allergens induces immediate-type hypersensitivity (IHS) following induction of Type 2 immune responses in animals and humans. Thymic stromal lymphopoietin (TSLP) derived f
Externí odkaz:
https://doaj.org/article/920e3f8142de4072bc7662329befb5c2