Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Hitoshi, Iwasaki"'
Autor:
Masako Baba, Kentaro Yoshida, Akihiko Nogami, Yuichi Hanaki, Yasuaki Tsumagari, Masayuki Hattori, Hideyuki Hasebe, Akito Shikama, Hitoshi Iwasaki, Noriyuki Takeyasu, Masaki Ieda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Although glucose metabolism and atrial fibrillation (AF) have complex interrelationships, the impact of catheter ablation of AF on glucose status has not been well evaluated. Continuous glucose monitoring (CGM) with a FreeStyle Libre Pro (Ab
Externí odkaz:
https://doaj.org/article/c1279f3bf97547da8485b795fd6e55ef
Autor:
Motohiro Sekiya, Yang Ma, Kenta Kainoh, Kenji Saito, Daichi Yamazaki, Tomomi Tsuyuzaki, Wanpei Chen, Putu Indah Paramita Adi Putri, Hiroshi Ohno, Takafumi Miyamoto, Yoshinori Takeuchi, Yuki Murayama, Yoko Sugano, Yoshinori Osaki, Hitoshi Iwasaki, Naoya Yahagi, Hiroaki Suzuki, Kaori Motomura, Takashi Matsuzaka, Kazuya Murata, Seiya Mizuno, Satoru Takahashi, Hitoshi Shimano
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112914- (2023)
Summary: The adaptive increase in insulin secretion in early stages of obesity serves as a safeguard mechanism to maintain glucose homeostasis that cannot be sustained, and the eventual decompensation of β cells is a key event in the pathogenesis of
Externí odkaz:
https://doaj.org/article/3b0c9249a97544358bb7aad112559fb6
A case of early-onset diabetes with impaired insulin secretion carrying a PAX6 gene Gln135* mutation
Autor:
Motohiro Sekiya, Mikiko Yuhara, Yuki Murayama, Mariko Ohyama Osawa, Rikako Nakajima, Nami Ohuchi, Nako Matsumoto, Daichi Yamazaki, Sayuri Mori, Takaaki Matsuda, Yoko Sugano, Yoshinori Osaki, Hitoshi Iwasaki, Hiroaki Suzuki, Hitoshi Shimano
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2022)
A paired homeodomain transcription factor, PAX6 (paired-box 6), is essential for the development and differentiation of pancreatic endocrine cells as well as ocular cells. Despite the impairment of insulin secretion observed in PAX6-deficient mice, e
Externí odkaz:
https://doaj.org/article/0eed796393954047a33fa981c92bedff
Autor:
Yasuhiro Suzuki, Hiroaki Suzuki, Tatsuya Ishikawa, Yasunori Yamada, Shigeru Yatoh, Yoko Sugano, Hitoshi Iwasaki, Motohiro Sekiya, Naoya Yahagi, Yasushi Hada, Hitoshi Shimano
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract We aimed to investigate the status of falls and to identify important risk factors for falls in persons with type 2 diabetes (T2D) including the non-elderly. Participants were 316 persons with T2D who were assessed for medical history, labor
Externí odkaz:
https://doaj.org/article/a7b1e405f14d44f2bd4da47baed2a423
Autor:
Takenao Koseki, Kazuki Nakajima, Hitoshi Iwasaki, Shigeki Yamada, Kazuo Takahashi, Yohei Doi, Tomohiro Mizuno
Publikováno v:
International Journal of Infectious Diseases, Vol 115, Iss , Pp 218-223 (2022)
Objectives: Favipiravir is an antiviral that is being evaluated for the treatment of COVID-19. Use of favipiravir is associated with elevation of serum uric acid levels. Risk factors for the occurrence of hyperuricemia are unclear. Methods: Specimens
Externí odkaz:
https://doaj.org/article/c22d30a61d6649de8e313e7f4e25aa1d
Autor:
Rikako Nakajima, Motohiro Sekiya, Yasuhisa Furuta, Takafumi Miyamoto, Masashi Sato, Kuniaki Fukuda, Keiichiro Hattori, Yasuhito Suehara, Mamiko Sakata-Yanagimoto, Shigeru Chiba, Yuka Okajima, Takashi Matsuzaka, Satoru Takase, Mikio Takanashi, Hiroaki Okazaki, Yusuke Takashima, Mikiko Yuhara, Yuta Mitani, Nako Matsumoto, Yuki Murayama, Mariko Ohyama Osawa, Nami Ohuchi, Daichi Yamazaki, Sayuri Mori, Yoko Sugano, Yoshinori Osaki, Hitoshi Iwasaki, Hiroaki Suzuki, Hitoshi Shimano
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-7 (2022)
In this study, we herein describe a 47-year-old Japanese woman who manifested inheritable non-alcoholic steatohepatitis (NASH) and severe dyslipidemia. Interestingly, her NASH progression was ameliorated by treatment with a sodium– glucose co-trans
Externí odkaz:
https://doaj.org/article/0027c2b79eba49c58dc15dcb46b8999b
Autor:
Yoshimi Nakagawa, Yunong Wang, Song-iee Han, Kanako Okuda, Asayo Oishi, Yuka Yagishita, Kae Kumagai, Hiroshi Ohno, Yoshinori Osaki, Yuhei Mizunoe, Masaya Araki, Yuki Murayama, Hitoshi Iwasaki, Morichika Konishi, Nobuyuki Itoh, Takashi Matsuzaka, Hirohito Sone, Nobuhiro Yamada, Hitoshi Shimano
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 949-971 (2021)
Background & Aims: cAMP responsive element-binding protein 3 like 3 (CREB3L3) is a membrane-bound transcription factor involved in the maintenance of lipid metabolism in the liver and small intestine. CREB3L3 controls hepatic triglyceride and glucose
Externí odkaz:
https://doaj.org/article/bce56fc30a3344359dbfa3a4b2fbc9ba
Autor:
Motohiro Sekiya, Takaaki Matsuda, Yuki Yamamoto, Yasuhisa Furuta, Mariko Ohyama, Yuki Murayama, Yoko Sugano, Yoshinori Ohsaki, Hitoshi Iwasaki, Naoya Yahagi, Shigeru Yatoh, Hiroaki Suzuki, Hitoshi Shimano
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Renal hypouricemia (RHUC) is a hereditary disorder where mutations in SLC22A12 gene and SLC2A9 gene cause RHUC type 1 (RHUC1) and RHUC type 2 (RHUC2), respectively. These genes regulate renal tubular reabsorption of urates while t
Externí odkaz:
https://doaj.org/article/0f0a62fe77bf4e94b6ab63c2550fa253
Publikováno v:
Sensors, Vol 22, Iss 23, p 9385 (2022)
The combination of magnetoresistive (MR) element and magnetic flux concentrators (MFCs) offers highly sensitive magnetic field sensors. To maximize the effect of MFC, the geometrical design between the MR element and MFCs is critical. In this paper,
Externí odkaz:
https://doaj.org/article/1d5be4fee2974473879c701e9051a410
Autor:
Soichiro Kawase, Yoshiyuki Okada, Kazushige Isono, Hitoshi Iwasaki, Takashi Kuno, Kohei Matsumura, Yiwen Fu, Yorikazu Harada, Tadashi Ogasawara
Publikováno v:
BMC Oral Health, Vol 19, Iss 1, Pp 1-5 (2019)
Abstract Background Antibiotic prophylaxis before invasive treatments, including dental extractions, is still recommended for patients at high risk of infective endocarditis. However, the risk from self-extraction of teeth in daily life of patients w
Externí odkaz:
https://doaj.org/article/301bb87d19db41b7b2df40111a3cb448