Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Hitoshi, Hori"'
Publikováno v:
Science and Technology of Advanced Materials, Vol 17, Iss 1, Pp 431-436 (2016)
We have developed a self-assembled fluorescent cluster comprising a seminaphthorhodafluor (SNARF) derivative protected by a photoremovable o-nitrobenzyl group. Prior to UV irradiation, a colorless and nonfluorescent cluster was spontaneously assemble
Externí odkaz:
https://doaj.org/article/7e358319add44c4a88400b53191882e7
Publikováno v:
Anticancer research. 42(8)
Boron tracedrugs possess global molecular tracking abilities and localized destructive power. We investigated the molecular properties of synthesized boron tracedrugs, including UTX-51, and their interactions with the advanced glycation end-product (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6146ad6c29f551fe5a68d109d841b21
https://pubmed.ncbi.nlm.nih.gov/35896254
https://pubmed.ncbi.nlm.nih.gov/35896254
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 9, Pp o694-o695 (2015)
The title compound, C25H31BF2N2O, is a potential boron tracedrug in boron neutron capture therapy (BNCT), in which the B atom adopts a distorted BN2F2 tetrahedral geometry: it is soluble in dimethyl sulfoxide, dimethylformamide and methanol. The pyrr
Externí odkaz:
https://doaj.org/article/5551cda0d12240ad909dce972cb5682c
Publikováno v:
Anticancer Research. 39:4479-4483
Background/aim The stereo-configuration (R-, S-configuration) of chiral-2-nitroimidazole derivatives alters their radiosensitizing activity. This study aimed at examining the molecular features of these enantiomers by molecular simulation techniques.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ebe84c2d39b6eb46305d327a7e066
https://doi.org/10.21873/anticanres.13622
https://doi.org/10.21873/anticanres.13622
Publikováno v:
Anticancer research. 40(8)
Background From the design and synthesis of enantiomers, we can expect to obtain two compounds with different pharmacokinetics and pharmacological activities at the same time, which is thought to lead to the development of efficient anticancer agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10352c525ea50ba4a06d24356adcb210
https://pubmed.ncbi.nlm.nih.gov/32727791
https://pubmed.ncbi.nlm.nih.gov/32727791
Publikováno v:
Journal of Pharmaceutical Sciences. 105:2298-2301
Boron neutron capture therapy (BNCT) is one of the numbers of radiotherapies for treatment of certain cancers. The ability of low-dose irradiation with neutrons or radioactive beams to provide an acceptable quality of life is an objective which has n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766fa732bc4f611b3f25c951543f9cdc
https://doi.org/10.1016/j.xphs.2016.06.005
https://doi.org/10.1016/j.xphs.2016.06.005
Publikováno v:
Anticancer research. 38(7)
Background/aim Sugar molecules are often used as a tool to structurally modify chemical compounds. The features of synthesized sugar-conjugated TX-1877 derivatives were herein examined. Materials and methods The molecular stabilities (reactivity) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b6f45340cef7d3f1f072370e0e2348
https://pubmed.ncbi.nlm.nih.gov/29970557
https://pubmed.ncbi.nlm.nih.gov/29970557
Publikováno v:
Anticancer Research. 37
BACKGROUND To date, two cyclo-oxygenase (COX) isoforms, COX1 and COX2, have been identified. In the present study, the COX-inhibitory activities of TX-1123 derivatives with the 2-hydroxyarylidene-4-cyclopentene-1,3-dione structure were examined, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5893d3839395e23538f3d898e4f23c7
https://doi.org/10.21873/anticanres.11764
https://doi.org/10.21873/anticanres.11764
Autor:
Chiaki Abe, Hitoshi Hori, Yukio Nagasaki, Ayaka Kawasaki, Yoshihiro Uto, Chiho Noguchi, Yoshio Endo, Ryo Tanaka, Toru Yoshitomi
Publikováno v:
Journal of Controlled Release. 182:67-72
Antioxidants have been demonstrated to exert beneficial effects as pharmacotherapies for cardiovascular diseases. The in vitro systems generally employed to evaluate antioxidants, however, are limited by having no appreciable in vivo redox status of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea92aac6656ed32eb3e16ab97050730
https://doi.org/10.1016/j.jconrel.2014.03.015
https://doi.org/10.1016/j.jconrel.2014.03.015
Autor:
Yoshihiro Uto, Eiji Nakata, Toshihiro Hashimoto, Takashi Morii, Maki Uwate, Yoshijiro Nazumi, Hideaki Maseda, Yasuko Okamoto, Yoshihiro Yukimachi, Hitoshi Hori
Publikováno v:
RSC Adv.. 4:348-357
In this study, we describe a rational design strategy to develop a latent ratiometric fluorescent pH probe from self-assembled seminaphthorhodafluor (SNARF) derivatives in aqueous conditions. Analysis of the characteristics of SNARF derivatives with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdd4c589395f7fa40465d9b1ae5e5420
https://doi.org/10.1039/c3ra43928c
https://doi.org/10.1039/c3ra43928c