Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hitomi Ueno-Yokohata"'
Autor:
Saki Aoto, Mayumi Hangai, Hitomi Ueno-Yokohata, Aki Ueda, Maki Igarashi, Yoshikazu Ito, Motoko Tsukamoto, Tomoko Jinno, Mika Sakamoto, Yuka Okazaki, Fuyuki Hasegawa, Hiroko Ogata-Kawata, Saki Namura, Kazuaki Kojima, Masao Kikuya, Keiko Matsubara, Kosuke Taniguchi, Kohji Okamura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Deep learning has rapidly been filtrating many aspects of human lives. In particular, image recognition by convolutional neural networks has inspired numerous studies in this area. Hardware and software technologies as well as large quantiti
Externí odkaz:
https://doaj.org/article/8e81eedb074040c79c3a2caf7c9ee8f6
Autor:
Hitomi Ueno-Yokohata, Hajime Okita, Keiko Nakasato, Chikako Kiyotani, Motohiro Kato, Kimikazu Matsumoto, Nobutaka Kiyokawa, Atsuko Nakazawa, Takako Yoshioka
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Detection of the tumor-specific EWSR1/FUS-ETS fusion gene is essential to diagnose Ewing sarcoma. Reverse transcription–polymerase chain reaction (RT–PCR) and fluorescence in situ hybridization are commonly used to detect the
Externí odkaz:
https://doaj.org/article/15b950b301c143b0be4a11442dd56f90
Autor:
Motohiro Kato, Susumu Goyama, Nobutaka Kiyokawa, Kenichiro Hata, Kimikazu Matsumoto, Toshio Kitamura, Seishi Ogawa, Takeshi Inukai, Junko Takita, Kentaro Ohki, Masafumi Seki, Ryota Shirai, Hitomi Ueno-Yokohata, Hiroe Kizawa, Toru Uchiyama, Hiroko Ogata-Kawata, Masahiro Migita, Kazuko Hamamoto, Shohei Yamamoto, Tsukasa Hori, Hiroyuki Takahashi, Akihiro Watanabe, Daisuke Tomizawa, Masanori Yoshida, Kohji Okamura, Kazuhiko Nakabayashi, Meri Uchiyama, Moe Tamura, Shin-ichi Tsujimoto, Tomoo Osumi
Translocations of retinoic acid receptor-α (RARA), typically PML–RARA, are a genetic hallmark of acute promyelocytic leukemia (APL). However, because a small fraction of APL lack translocations of RARA, we focused here on APL cases without RARA tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a48a08deebf9face976104eb1bf03c3
https://doi.org/10.1158/0008-5472.c.6510653.v1
https://doi.org/10.1158/0008-5472.c.6510653.v1
Autor:
Motohiro Kato, Susumu Goyama, Nobutaka Kiyokawa, Kenichiro Hata, Kimikazu Matsumoto, Toshio Kitamura, Seishi Ogawa, Takeshi Inukai, Junko Takita, Kentaro Ohki, Masafumi Seki, Ryota Shirai, Hitomi Ueno-Yokohata, Hiroe Kizawa, Toru Uchiyama, Hiroko Ogata-Kawata, Masahiro Migita, Kazuko Hamamoto, Shohei Yamamoto, Tsukasa Hori, Hiroyuki Takahashi, Akihiro Watanabe, Daisuke Tomizawa, Masanori Yoshida, Kohji Okamura, Kazuhiko Nakabayashi, Meri Uchiyama, Moe Tamura, Shin-ichi Tsujimoto, Tomoo Osumi
Supplementary Methods: IRB approval, Genomic analysis, Identification of translocations and determination of their breakpoints, Plasmids Construct, Cell line and reagent, Co-immunoprecipotation and immunoblotting analysis, Luciferase assay, Retroviru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c87a9fa2073a3585c3ebb31a2e68bc2
https://doi.org/10.1158/0008-5472.22420451.v1
https://doi.org/10.1158/0008-5472.22420451.v1
Autor:
Atsuko Nakazawa, Takako Yoshioka, Chikako Kiyotani, Nobutaka Kiyokawa, Kimikazu Matsumoto, Keiko Nakasato, Motohiro Kato, Hajime Okita, Hitomi Ueno-Yokohata
Publikováno v:
Diagnostic Pathology
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-10 (2021)
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-10 (2021)
Background Detection of the tumor-specific EWSR1/FUS-ETS fusion gene is essential to diagnose Ewing sarcoma. Reverse transcription–polymerase chain reaction (RT–PCR) and fluorescence in situ hybridization are commonly used to detect the fusion ge
Autor:
Yoshikazu Ito, Kohji Okamura, Maki Igarashi, Saki Namura, Hitomi Ueno-Yokohata, Fuyuki Hasegawa, Hiroko Ogata-Kawata, Aki Ueda, Masao Kikuya, Mika Sakamoto, Kazuaki Kojima, Keiko Matsubara, Kosuke Taniguchi, Motoko Tsukamoto, Yuka Okazaki, Tomoko Jinno, Mayumi Hangai, Saki Aoto
Publikováno v:
Scientific reports. 12(1)
Deep learning has rapidly been filtrating many aspects of human lives. In particular, image recognition by convolutional neural networks has inspired numerous studies in this area. Hardware and software technologies as well as large quantities of dat
Autor:
Osamu Miyazaki, Yoko Shioda, Motohiro Kato, Nobutaka Kiyokawa, Hajime Okita, Yuji Yamada, Keita Terashima, Takako Yoshioka, Hitomi Ueno-Yokohata, Chikako Kiyotani, Tomoo Osumi, Kimikazu Matsumoto, Keiko Nakasato, Satoshi Yoshimura, Tomoro Hishiki, Ryota Shirai, Shinichi Tsujimoto
Publikováno v:
Genes, Chromosomes and Cancer. 57:525-529
Clear cell sarcoma of the kidney (CCSK) is the second most common renal malignancy in children. The prognosis is poorer in CCSK than in Wilms' tumor, and multimodal treatment including surgery, intensive chemotherapy, and radiation is required to imp
Autor:
Hiroko Ogata-Kawata, Moe Tamura, Kimikazu Matsumoto, Toshio Kitamura, Nobutaka Kiyokawa, Junko Takita, Takeshi Inukai, Seishi Ogawa, Akihiro Watanabe, Toru Uchiyama, Shinichi Tsujimoto, Hitomi Ueno-Yokohata, Masahiro Migita, Hiroe Kizawa, Motohiro Kato, Ryota Shirai, Kentaro Ohki, Kohji Okamura, Daisuke Tomizawa, Tomoo Osumi, Kazuhiko Nakabayashi, Tsukasa Hori, Susumu Goyama, Hiroyuki Takahashi, Masafumi Seki, Kenichiro Hata, Meri Uchiyama, Kazuko Hamamoto, Masanori Yoshida, Shohei Yamamoto
Publikováno v:
Cancer Research. 78:4452-4458
Translocations of retinoic acid receptor-α (RARA), typically PML–RARA, are a genetic hallmark of acute promyelocytic leukemia (APL). However, because a small fraction of APL lack translocations of RARA, we focused here on APL cases without RARA tr
Autor:
Meri Uchiyama, Tomoro Hishiki, Shinichi Tsujimoto, Keita Terashima, Dai Keino, Masahiro Sekiguchi, Yoko Shioda, Takao Deguchi, Shuichi Ito, Kentaro Ohki, Chikako Kiyotani, Daisuke Tomizawa, Hideki Ogiwara, Takako Yoshioka, Hitomi Ueno-Yokohata, Junko Takita, Tomoo Osumi, Toru Uchiyama, Kaoru Yoshida, Motohiro Kato, Kenichiro Watanabe, Nobutaka Kiyokawa, Seishi Ogawa, Masanori Yoshida, Kimikazu Matsumoto, Ryota Shirai, Hajime Okita
Publikováno v:
Neuro-Oncology
BACKGROUND Genetic hallmark of atypical teratoid/rhabdoid tumor (AT/RT) is loss-of-function variants or deletions in SMARCB1 gene on 22q11.2 chromosome, which is common to extracranial malignant rhabdoid tumors (MRT). Previous studies demonstrated th
Autor:
Toshiaki Shimizu, Kazuki Terada, Akinori Yaguchi, Nobutaka Kiyokawa, Kentaro Ohki, Yuya Saito, Atsushi Manabe, Hitomi Ueno-Yokohata, Junya Fujimura, Takeshi Ishibashi
Publikováno v:
International Journal of Hematology. 106:269-281
ZNF384-related fusion genes are associated with a distinct subgroup of B-cell precursor acute lymphoblastic leukemias in childhood, with a frequency of approximately 3-4%. We previously identified a novel EP300-ZNF384 fusion gene. Patients with the Z