Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hitomi Takao"'
Autor:
Kenji J. Tsuchiya, B. P. Riley, Pak C. Sham, Yasuhide Iwata, Andrew Makoff, Genichi Sugihara, Mizuho Nakajima, Takeo Yoshikawa, Hitomi Takao, Norio Mori, Yoshimi Iwayama, Kazuhiko Nakamura, Nori Takei, Hideo Matsuzaki, Shiro Suda, Kazuo Yamada, Yoshimoto Sekine, David A. Collier, Ronald Y.L. Chen, Katsuaki Suzuki
Publikováno v:
Neuroscience Research. 57:194-202
Several previous studies have reported a significant linkage between markers in the alpha 7 nicotinic cholinergic receptor subunit ( CHRNA7 ) gene and either schizophrenia or the P50 sensory gating deficit, a schizophrenia endophenotype. However, CHR
Autor:
Hisako Ohba, Takeo Yoshikawa, Noriaki Nakatani, Eiji Hattori, Teruhiko Higuchi, Hitomi Takao, Yoshio Minabe, Kazuo Yamada, Tetsuo Ohnishi, Sevilla D. Detera-Wadleigh, Yoshimi Iwayama, Tomoko Toyota
Publikováno v:
Biological Psychiatry. 60:192-201
Background Genetic variations in the serotonin receptor 3A (HTR3A) and 3B (HTR3B) genes, positioned in tandem on chromosome 11q23.2, have been shown to be associated with psychiatric disorders in samples of European ancestry. But the polymorphisms hi
Autor:
Masaomi Iyo, Kazuhiko Nakamura, Yoshimi Iwayama-Shigeno, Eiji Shimizu, Manabu Toyoshima, Masanari Itokawa, Kazuo Yamada, Kenji Hashimoto, Akira Okuno, Norio Mori, Tomoko Toyota, Hitomi Takao, Tetsuo Ohnishi, Takeo Yoshikawa, Hisako Ohba, Yoshio Minabe
Publikováno v:
Biological Psychiatry. 57:1493-1503
Background We previously reported a reduction in serum levels of d -serine, an endogenous co-agonist of the N-methyl-D-aspartate (NMDA) receptor, in schizophrenia, supporting the hypofunction hypothesis of NMDA neurotransmission in schizophrenia. In
Autor:
Takeo Yoshikawa, Tomoko Toyota, Taiichi Katayama, Norio Mori, Kousuke Baba, Ko Miyoshi, Yoshimi Iwayama-Shigeno, Eiji Hattori, Kazuo Yamada, Akiko Honda, Yoshimoto Sekine, Kazuhiko Nakamura, Masaya Tohyama, Katsuaki Suzuki, Yasuhide Iwata, Yoshio Minabe, Hitomi Takao, Noriyoshi Takei
Publikováno v:
Biological Psychiatry. 56:683-690
Background DISC1 has been suggested as a causative gene for psychoses in a large Scottish family. We recently identified FEZ1 as an interacting partner for DISC1. To investigate the role of FEZ1 in schizophrenia and bipolar disorder, case–control a
Autor:
Takeo Yoshikawa, Tatsuyuki Muratake, Yoshio Minabe, Norio Mori, Toshiyuki Someya, Takashi Asada, Tadafumi Kato, Yoshimi Iwayama-Shigeno, Hitomi Takao, Masayuki Ide, Kazuo Yamada, Tomoko Toyota, Kazuya Iwamoto, Naoshi Kaneko, Kazuhiko Nakamura
Publikováno v:
Biological Psychiatry. 56:462-465
Background Wnt signaling plays important roles in neurodevelopmental processes. Frizzled is a receptor of Wnt protein, and the Frizzled 3 ( FZD3 ) gene was recently reported to be associated with schizophrenia. Our study attempted to confirm associat
Autor:
Kazuo Yamada, Miki Bundo, Takeo Yoshikawa, Tadafumi Kato, Yoshimi Iwayama, Hitomi Takao, Kazuya Iwamoto
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (5)
Downregulation of oligodendrocyte-related genes in postmortem brains of patients with schizophrenia has been reported by several DNA microarray studies. We recently reported that enhanced DNA methylation of SOX10, which encodes a transcription factor
Autor:
Tadafumi Kato, Hitomi Takao, Kazuya Iwamoto, Kazuo Yamada, Yoshimi Iwayama-Shigeno, Miki Bundo, Takeo Yoshikawa
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 25(22)
Downregulation of oligodendrocyte-related genes, referred to as oligodendrocyte dysfunction, in schizophrenia has been revealed by DNA microarray studies. Because oligodendrocyte-specific transcription factors regulate the differentiation of oligoden
Autor:
Masayuki, Fukasawa, Mika, Aoki, Kazuo, Yamada, Yoshimi, Iwayama-Shigeno, Hitomi, Takao, Joanne, Meerabux, Tomoko, Toyota, Toru, Nishikawa, Takeo, Yoshikawa
Publikováno v:
Journal of medical and dental sciences. 51(2)
The exact etiology of schizophrenia remains undetermined but accumulating evidence suggests that disturbances in neurodevelopment may represent one contributory factor. Netrin G1, a recently cloned gene from the mouse, has been shown to play a potent
Autor:
Kenjiro Seki, Kazuya Iwamoto, Kazuo Yamada, Takeo Yoshikawa, Joanne M.A. Meerabux, Tadafumi Kato, Sachiko Nishimura, Mika Aoki-Suzuki, Hisako Ohba, Hitomi Takao, Yoshimi Iwayama-Shigeno, Noriaki Nakatani, Brian Dean, Shigeyoshi Itohara, Yumiko Suto, Toru Nishikawa, Tomoko Toyota
Publikováno v:
Biological psychiatry. 57(4)
Background The netrin-G1 ( NTNG1 ) and -G2 ( NTNG2 ) genes, recently cloned from mouse, play a role in the formation and/or maintenance of glutamatergic neural circuitry. Accumulating evidence strongly suggests that disturbances of neuronal developme