Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hitomi Sekine"'
Autor:
Miwa Nahata, Sachiko Mogami, Hitomi Sekine, Seiichi Iizuka, Naoto Okubo, Naoki Fujitsuka, Hiroshi Takeda
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Chronic undernutrition contributes to the increase in frailty observed among elderly adults, which is a pressing issue in the sector of health care for older people worldwide. Autophagy, an intracellular recycling system, is closely associat
Externí odkaz:
https://doaj.org/article/2976f3861c604a40a8c972724066b04e
Autor:
Miwa Nahata, Naoki Fujitsuka, Hitomi Sekine, Chika Shimobori, Katsuya Ohbuchi, Seiichi Iizuka, Sachiko Mogami, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Malnutrition impairs basic daily activities and leads to physical frailty, which is aggravated in the elderly compared with young adults. It is also well-known that the elderly are more vulnerable to metabolic stress. Therefore, in this study, using
Externí odkaz:
https://doaj.org/article/826f08799ed24f58a4c998facfea729e
Autor:
Chinami, Matsumoto, Hitomi, Sekine, Miwa, Nahata, Sachiko, Mogami, Katsuya, Ohbuchi, Naoki, Fujitsuka, Hiroshi, Takeda
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:780-792
Muscle atrophy is commonly observed during cisplatin chemotherapy, leading to a reduced QOL in cancer patients. Reduced skeletal muscle mass caused by cisplatin treatment results from the activation of ubiquitin ligases-Atrogin-1 and MuRF1, but the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a83e70f5ba40a669bb421a7c3d5f157
https://doi.org/10.1248/bpb.b22-00171
https://doi.org/10.1248/bpb.b22-00171
Autor:
Chinami Matsumoto, Hitomi Sekine, Nana Zhang, Sachiko Mogami, Naoki Fujitsuka, Hiroshi Takeda
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9176
Chemotherapy-induced sarcopenia is an unfavorable prognostic factor implicated in the development of postoperative complications and reduces the quality of life of patients with cancer. Skeletal muscle loss due to cisplatin use is caused by mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a8fd6c213d23f4f8e5e4ce64577621
https://doi.org/10.3390/ijms24119176
https://doi.org/10.3390/ijms24119176
Autor:
Yoshihisa Sugimura, Yohei Kume, Hiroko Sakuma, Mitsuaki Hosoya, Makoto Sumikoshi, Hitomi Sekine
Publikováno v:
Clinical Pediatric Endocrinology
Childhood-onset lymphocytic infundibuloneurohypophysitis (LINH) due to infiltration of autoimmune lymphocyte in the neurohypophysis is rarely reported. Its definitive diagnosis requires a pituitary biopsy, which is an invasive procedure. Recently, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548f8d1d9c7fed8e17215a75a8831695
https://doi.org/10.1297/cpe.30.65
https://doi.org/10.1297/cpe.30.65
Autor:
Kunitsugu Kubota, Yumi Harada, Hitomi Sekine, Naoki Fujitsuka, Seiichi Iizuka, Daichi Sadatomi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111860-(2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d90c10339b0ee2d6045635fe38fa9aa
http://www.sciencedirect.com/science/article/pii/S0753332221006429
http://www.sciencedirect.com/science/article/pii/S0753332221006429
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 369:466-472
Taste stimulants play important roles in triggering digestion and absorption of nutrients and in toxin detection, under the control of the gut-brain axis. Bitter compounds regulate gut hormone secretion and gastrointestinal motility through bitter ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbe43e728f05fd38fd29eac08afcfde
https://doi.org/10.1124/jpet.118.256008
https://doi.org/10.1124/jpet.118.256008
Autor:
Taro, Oshiro, Yumi, Harada, Kunitsugu, Kubota, Daichi, Sadatomi, Hitomi, Sekine, Mitsue, Nishiyama, Naoki, Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy. 152:113263
Changes in the intestinal microbiota are known to occur in constipated patients. Dietary fiber restriction presents obstacles to appropriate defecation and affects fecal properties, but the relationship between fecal microbiota and fecal morphologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6b77b076925664c37e96f887949d5
https://doi.org/10.1016/j.biopha.2022.113263
https://doi.org/10.1016/j.biopha.2022.113263
Autor:
Sachiko Mogami, Miwa Nahata, Hitomi Sekine, Naoki Fujitsuka, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Gastroenterology. 162:S-1050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4d3af3162eb294d96ea9129578371c
https://doi.org/10.1016/s0016-5085(22)62500-9
https://doi.org/10.1016/s0016-5085(22)62500-9
Autor:
Miwa Nahata, Naoki Fujitsuka, Hitomi Sekine, Katsuya Ohbuchi, Sachiko Mogami, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Gastroenterology. 162:S-1055
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef66b728ebc5c7ba8acb6ec1f8b8aa10
https://doi.org/10.1016/s0016-5085(22)62517-4
https://doi.org/10.1016/s0016-5085(22)62517-4