Výsledky vyhledávání - "Hitomi Seino"

Exploring Molecular Mechanisms Involved in the Development of the Depression-Like Phenotype in Interleukin-18-Deficient Mice

Autor: Seishi Maeda, Wen Li, Kyosuke Yamanishi, Keiichiro Mukai, Hisato Matsunaga, Yuko Watanabe, Hitomi Seino, Sachi Kuwahara-Otani, Haruki Okamura, Masahiro Miyauchi, Hiromichi Yamanishi, Masaki Hata, Takuya Hashimoto, Naomi Gamachi, Noriko Uwa, Hideshi Yagi

Publikováno v: BioMed Research International, Vol 2021 (2021)
BioMed Research International

Interleukin-18 (IL-18) is an inflammatory cytokine that has been linked to energy homeostasis and psychiatric symptoms such as depression and cognitive impairment. We previously revealed that deficiency in IL-18 led to hippocampal abnormalities and r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3f727882633ac83157db4c93ade924
https://doaj.org/article/9fbe864060a94699b1ae5f0adc544fb9

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A potential drug interaction between phenobarbital and dolutegravir: A case report

Autor: Shota Shimabukuro, Noriko Uwa, Kyoko Hideta, Takeshi Kimura, Shinichi Hikasa, Satoshi Higasa, Tazuko Tokugawa, Akihiro Sawada, Hitomi Seino

Publikováno v: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 24(6)

In this report, we describe a human immunodeficiency virus (HIV)-infected patient in whom changes in phenobarbital (PB) dosage resulted in associated changes in plasma concentrations of dolutegravir (DTG). His plasma concentrations of DTG were 0.934,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32112ce6d351936560dbb510b0fe4b3
https://pubmed.ncbi.nlm.nih.gov/29415844

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IL-18 mediates the formation of stress-induced, histamine-dependent gastric lesions

Autor: Masahiro Kokai, Hitomi Seino, Shin-ichiro Kashiwamura, Yoshio Morita, Noriko M. Tsuji, Haruki Okamura, Haruyasu Ueda

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 292:G262-G267

A role of IL-18 in the induction of gastric lesions by water immersion and restraint stress (WRS) was investigated. When wild-type BALB/c mice were exposed to WRS, levels of IL-18 in the serum and stomach increased rapidly with the development of acu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d1de0544c0e26029dd984501e78b0d
https://doi.org/10.1152/ajpgi.00588.2005

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