Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hitomi Kawaji"'
Autor:
Mamoru Ito, Makoto Kubo, Hitomi Kawaji, Yoshiki Otsubo, Kanako Kurata, Hikaru Abutani, Mikita Suyama, Yoshinao Oda, Tomoharu Yoshizumi, Masafumi Nakamura, Eishi Baba
Publikováno v:
Cancers, Vol 15, Iss 23, p 5608 (2023)
Background: Comprehensive genomic profiling (CGP) has become generally accepted practice in cancer care since CGP has become reimbursed by national healthcare insurance in Japan in 2019. However, its usefulness for cancer patients is insufficient for
Externí odkaz:
https://doaj.org/article/3e5f187188084319808f6baf7f57a568
Autor:
Kimihisa Mizoguchi, Hitomi Kawaji, Masaya Kai, Takafumi Morisaki, Saori Hayashi, Yuka Takao, Mai Yamada, Akiko Shimazaki, Tomofumi Osako, Nobuyuki Arima, Masayuki Okido, Yoshinao Oda, Masafumi Nakamura, Makoto Kubo
Publikováno v:
Cancers, Vol 15, Iss 18, p 4456 (2023)
Tumor-infiltrating lymphocytes in the tumor microenvironment are important in the treatment of triple-negative breast cancer (TNBC). Cytotoxic T cells produce cytokines and cytotoxic factors, such as perforin and granzyme, which induce apoptosis by d
Externí odkaz:
https://doaj.org/article/4462200e40124282bc7b3ee3feedb952
Autor:
Karen Zaguirre, Masaya Kai, Makoto Kubo, Mai Yamada, Kanako Kurata, Hitomi Kawaji, Kazuhisa Kaneshiro, Yurina Harada, Saori Hayashi, Akiko Shimazaki, Takafumi Morisaki, Hitomi Mori, Yoshinao Oda, Sanmei Chen, Taiki Moriyama, Shuji Shimizu, Masafumi Nakamura
Publikováno v:
Cancer Medicine, Vol 10, Iss 5, Pp 1605-1613 (2021)
Abstract Introduction PREDICT is a prognostication tool that calculates the potential benefit of various postsurgical treatments on the overall survival (OS) of patients with nonmetastatic invasive breast cancer. Once patient, tumor, and treatment de
Externí odkaz:
https://doaj.org/article/2dc3326665694cc4ba9b344e1205d2cd
Autor:
Hitomi Kawaji, Makoto Kubo, Nami Yamashita, Hidetaka Yamamoto, Masaya Kai, Atsuko Kajihara, Mai Yamada, Kanako Kurata, Kazuhisa Kaneshiro, Yurina Harada, Saori Hayashi, Akiko Shimazaki, Hitomi Mori, Sayuri Akiyoshi, Eiji Oki, Yoshinao Oda, Eishi Baba, Masaki Mori, Masafumi Nakamura
Publikováno v:
Cancer Medicine, Vol 10, Iss 2, Pp 529-539 (2021)
Abstract Precision oncology with next generation sequencing (NGS) using tumor tissue with or without blood has begun in Japan. Tumor molecular profiling tests are available, including the OncoGuide™ NCC Oncopanel System and FoundationOne® CDx (F1C
Externí odkaz:
https://doaj.org/article/6ac2cc31b7044240b2771eebafd0e22a
Autor:
Yoshihiko Sadakari, Satomi Date, Soichiro Murakami, Shu Ichimiya, Shiho Nishimura, Hitomi Kawaji, Akiko Sagara, Jaymel R Castillo, Mikimasa Ishikawa, Tetsuro Kamimura, Akihiko Uchiyama, Masafumi Nakamura
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 2, Iss 2, Pp 59-65 (2018)
Objectives: Non-surgical treatment is an acceptable approach for managing appendiceal abscess in adults. However, it is only applicable for selected patients, and conversion to surgery is mandatory for failed conservative treatment. This study aimed
Externí odkaz:
https://doaj.org/article/c4043807c135403ab1e77bd4015487ef
Autor:
Akiko, Shimazaki, Makoto, Kubo, Kanako, Kurata, Yuka, Takao, Saori, Hayashi, Yurina, Harada, Hitomi, Kawaji, Kazuhisa, Kaneshiro, Mai, Yamada, Masaya, Kai, Masafumi, Nakamura
Publikováno v:
Anticancer Research. 42:4071-4077
Abnormalities in the cyclin D1-CDK4/6 complex have been implicated in breast cancer proliferation and resistance to treatment. Recently, new drugs have been developed to target CDK4/6. Meanwhile, liquid biopsy has received great interest in oncology.
Autor:
Takafumi Morisaki, Karen Zaguirre, Masaya Kai, Hitomi Kawaji, Hitomi Mori, Makoto Kubo, Shuji Shimizu, Sanmei Chen, Mai Yamada, Kanako Kurata, Masafumi Nakamura, Akiko Shimazaki, Yoshinao Oda, Taiki Moriyama, Yurina Harada, Saori Hayashi, Kazuhisa Kaneshiro
Publikováno v:
Cancer Medicine, Vol 10, Iss 5, Pp 1605-1613 (2021)
Cancer Medicine
Cancer Medicine
Introduction PREDICT is a prognostication tool that calculates the potential benefit of various postsurgical treatments on the overall survival (OS) of patients with nonmetastatic invasive breast cancer. Once patient, tumor, and treatment details hav
Autor:
Eishi Baba, Nami Yamashita, Atsuko Kajihara, Sayuri Akiyoshi, Hidetaka Yamamoto, Hitomi Kawaji, Hitomi Mori, Eiji Oki, Yurina Harada, Mai Yamada, Masaya Kai, Makoto Kubo, Saori Hayashi, Kazuhisa Kaneshiro, Yoshinao Oda, Masaki Mori, Kanako Kurata, Masafumi Nakamura, Akiko Shimazaki
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 2, Pp 529-539 (2021)
Cancer Medicine, Vol 10, Iss 2, Pp 529-539 (2021)
Precision oncology with next generation sequencing (NGS) using tumor tissue with or without blood has begun in Japan. Tumor molecular profiling tests are available, including the OncoGuide™ NCC Oncopanel System and FoundationOne® CDx (F1CDx). Our
Autor:
Kanako Kurata, Takafumi Morisaki, Yuan Yuan, Yurina Harada, Masafumi Nakamura, Akiko Shimazaki, Makoto Kubo, Hitomi Kawaji, Saori Hayashi, Mai Yamada, Kazuhisa Kaneshiro, Masaya Kai
Publikováno v:
Cancer Research. 80:P4-09
Background: Immune checkpoint inhibitors (ICIs) has become a new promising treatment in the field of cancer therapy. Therefore, it is important to identify predictors of effect for ICIs in breast cancers (BC). PD-L1 expression and the abundance of TI
Autor:
Hitomi Kawaji, Masafumi Nakamura, Akiko Shimazaki, Mai Yamada, Yoshinao Oda, Masaya Kai, Nami Yamashita, Eiji Baba, Saori Hayashi, Kazuhisa Kaneshiro, Makoto Kubo, Kanako Kurata, Yurina Harada
Publikováno v:
Cancer Research. 80:P4-09
Background: Oncogenic genetic alterations leading to identify patients who may benefit from the target therapy are essential biomarkers for them, and to review widely what kind of driver gene alteration that each cancer has is important for effective